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International immunopharmacology, ISSN 1567-5769, 11/2013, Volume 17, Issue 3, pp. 638 - 650
Signaling | Receptors | Inflammation | Kinases | Neutrophils | Pharmacology & Pharmacy | Immunology | Life Sciences & Biomedicine | Science & Technology | Signal Transduction - immunology | Animals | Receptors, Cell Surface - immunology | Humans | Neutrophils - immunology | Selectins - immunology | Mycoses | Lectins | Fc receptors | Integrins | Index Medicus | FcR, Fc-receptor | GPI, glycosylphosphatidylinositol anchor | CLEC, C-type lectin | OSCAR, osteoclast-associated receptor | PKB, protein kinase B | DAG, diacyl-glycerol | Tyk2, tyrosine protein kinase 2 | VCAM-1, vascular cell adhesion molecule 1 | ICAM-1, intercellular adhesion molecule 1 | FADD, Fas-associated protein with death domain | IκB, inhibitor of NF-κB | GM-CSF, granulocyte | MyD88, myeloid differentiation protein 88 | TNF, tumor necrosis factor | LTβ, lymphotoxin β | TRADD, TNFR1-associated death domain protein | Abl, Abelson leukemia proto-oncogene | SLP-76, SH2 domain-containing leukocyte protein of 76 kDa | CALDAG-GEFI, calcium and DAG-regulated guanine nucleotide exchange factor I | IL, interleukin | Src, Rous sarcoma virus proto-oncogene | IRF, IFN regulatory factor | RIG, retinoic acid-inducible gene | PLC, phospholipase C | TCR, T-cell receptor | IKK, IκB kinase | ITAM, immunoreceptor tyrosine-based activation motif | CARD, caspase activation and recruitment domain | IP3, inositol-tris-phosphate | CHO, Chinese hamster ovary cells | MKK, MAP kinase kinase | fMLP, formly-Met-Leu-Phe | TRAF, TNF receptor-associated factor | MIP, macrophage inflammatory protein | Rac, Ras-related C3 botulinum toxin substrate | monocyte colony-stimulating factor | PIP3, phosphatidylinositol-3-phosphate | VLA-4, very late antigen 4 (α4β1 integrin) | PAF, platelet activating factor | STAT, signal transducer and activator of transcription | TAK, TGFβ-activated kinase 1 | Mac-1, macrophage antigen 1 (αMβ2 integrin) | FcRγ, Fc-receptor γ-chain | Asc, apoptosis-associated speck-like protein containing a CARD | cIAP, cellular inhibitor of apoptosis | BCR, B-cell receptor | Fgr, Gardner–Rasheed feline sarcoma proto-oncogene | VASP, vasodilator-stimulated phosphoprotein | Hck, hematopoietic cell kinase | TGFβ, transforming growth factor β | Rap, Ras-related protein | SHP-1, SH2 domain-containing protein tyrosine phosphatase 1 | Syk, spleen tyrosine kinase | GPCR, G protein-coupled receptor | G-CSF, granulocyte colony-stimulating factor | TREM, triggering receptor expressed on myeloid cells | DISC, death-inducing signaling complex | MDL-1, myeloid DAP12-associating lectin 1 | C3G, Crk SH3 domain-binding guanine nucleotide exchange factor (RapGEF1) | NF-κB, nuclear factor κB | ERM, ezrin-radixin-moesin | Epac1, exchange protein activated by cyclic AMP 1 | LTB4, leukotriene B4 | Mcl, macrophage C-type lectin | SAP130, Sin3A-associated protein of 130 kDa | SH2, Src-homology 2 domain | MAP kinase, mitogen-activated protein kinase | PSGL-1, P-selectin glycoprotein ligand | PI3K, phoshoinositide-3-kinase | ADAP, adhesion and degranulation promoting adapter protein (Fyb, SLAP-130) | NLRP3, NOD-like receptor family, pyrin domain containing 3 | MDA5, melanoma differentiation-associated protein 5 | TLR, Toll-like receptor | GRK, GPCR kinase | LAD, leukocyte adhesion deficiency | MAPKAP-kinase, MAP kinase-associated protein kinase | ZAP-70, ζ-chain-associated protein of 70 kDa | TRAIL, TNF-related apoptosis-inducing ligand | JNK, c-Jun N-terminal kinase | LFA-1, lymphocyte function-associated receptor 1 (αLβ2 integrin) | ROS, reactive oxygen species | RIP3, receptor-interacting serine-threonine protein kinase 3 | DAP12, DNAX activating protein 12 | IFN, interferon | PIR, paired immunoglobulin-like receptor | PKC, protein kinase C | PAK, p21-activated kinase | ESL-1, E-selectin ligand 1 | GAP, GTPase activating protein | ERK, extracellular signal-regulated kinase | SOCS, suppressor of cytokine signaling | JAK, Janus kinase | RANK, receptor activator of NF-κB | IRAK, IL-1 receptor-associated kinase | NOD, nucleotide-binding oligomerization domain containing protein | CEACAM3, carcinoembryonic antigen-related cell adhesion molecule 3 (CD66b)
Journal Article
FEBS letters, ISSN 0014-5793, 09/2018, Volume 592, Issue 18, pp. 3092 - 3100
cell growth | SHP‐1 | gastric cancer | RING finger protein 38 | STAT3 | SHP-1 | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Stomach Neoplasms - genetics | Cell Proliferation - genetics | Humans | Kaplan-Meier Estimate | Stomach Neoplasms - therapy | Stomach Neoplasms - metabolism | Xenograft Model Antitumor Assays - methods | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - genetics | Cycloheximide - pharmacology | RNAi Therapeutics - methods | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Ubiquitination - drug effects | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - metabolism | Mice, Nude | Protein Stability - drug effects | Cell Line, Tumor | Cell Proliferation - drug effects | Gene Expression Regulation, Neoplastic - drug effects | Protein Synthesis Inhibitors - pharmacology | Index Medicus
Journal Article
Journal of cellular biochemistry, ISSN 0730-2312, 10/2017, Volume 118, Issue 10, pp. 3290 - 3298
APOPTOSIS | SHP‐1 | CROCIN | STAT3 | SHP-1 | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Apoptosis - drug effects | Humans | Apoptosis - genetics | G1 Phase - drug effects | Multiple Myeloma - metabolism | Neoplasm Proteins - metabolism | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - genetics | Carotenoids - pharmacology | Enzyme Induction - genetics | Multiple Myeloma - drug therapy | Multiple Myeloma - pathology | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - metabolism | Enzyme Induction - drug effects | G1 Phase - genetics | HeLa Cells | Neoplasm Proteins - genetics | Multiple Myeloma - genetics | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Tyrosine | Phenols | Phosphatases | Gene expression | Vascular endothelial growth factor | Multiple myeloma | Cell proliferation | Bax protein | Bcl-2 protein | SHP-1 protein | Activation | Cyclin D1 | Kinases | Phosphatase | Nuclei | Prevention | Proteins | Angiogenesis | Signal transduction | Janus kinase 2 | Cell cycle | Janus kinase | Saffron | Inhibition | G1 phase | Translocation | Pervanadate | Stat3 protein | Src protein | CXCR4 protein | Inhibitors | Protein phosphatase | Protein-tyrosine-phosphatase | Apoptosis | Index Medicus
Journal Article
Immunity (Cambridge, Mass.), ISSN 1074-7613, 04/2017, Volume 46, Issue 4, pp. 635 - 648
myeloid cells | SYK | RIPK3 | MLKL | autoinflammation | Ptpn6 | IL-1β | IL-1α | MyD88 | SHP1 | TAK1 | necrosis | RIPK1 | Life Sciences & Biomedicine | Immunology | Science & Technology | Receptor-Interacting Protein Serine-Threonine Kinases - metabolism | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - immunology | Phosphorylation | Interleukin-1alpha - immunology | Skin Diseases - genetics | Humans | Immunoblotting | Interleukin-1alpha - metabolism | Syk Kinase - immunology | Signal Transduction - immunology | Inflammation - metabolism | Flow Cytometry | Syk Kinase - genetics | HEK293 Cells | Myeloid Differentiation Factor 88 - immunology | Interleukin-1alpha - genetics | Receptor-Interacting Protein Serine-Threonine Kinases - immunology | Skin Diseases - metabolism | MAP Kinase Kinase Kinases - genetics | Receptors, Interleukin-1 - immunology | Myeloid Differentiation Factor 88 - genetics | Skin Diseases - immunology | Inflammation - immunology | MAP Kinase Kinase Kinases - metabolism | Signal Transduction - genetics | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - genetics | MAP Kinase Kinase Kinases - immunology | Mice, Knockout | Receptors, Interleukin-1 - metabolism | Models, Immunological | Receptor-Interacting Protein Serine-Threonine Kinases - genetics | Syk Kinase - metabolism | Animals | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - metabolism | Inflammation - genetics | Mutation | Myeloid Differentiation Factor 88 - metabolism | Disease | SHP-1 protein | Crosstalk | Interleukin | Licenses | Interleukin 1 receptors | Kinases | Phosphatase | Inflammatory diseases | Proteins | Coding | Rodents | Interleukin 1 | Post-translation | Bone marrow | Skin diseases | Tumor necrosis factor-TNF | Protein-tyrosine kinase | Activation analysis | Immune system | Tyrosine | TAK1 protein | Neutrophils | Leukocytes (neutrophilic) | Inflammation | Roles | Scaffolding | Point mutation | MyD88 protein | Syk protein | Index Medicus
Journal Article
FEBS letters, ISSN 0014-5793, 2010, Volume 584, Issue 10, pp. 1989 - 1996
Cyclophilin D | Permeability transition pore | Kinase | Chaperone | Channel | Apoptosis | PTEN induced kinase 1 | cyclophilin D | inner mitochondrial membrane | outer mitochondrial membrane | cyclosporin A | adenine nucleotide translocator | GSK3 | permeability transition pore | extracellular signal regulated kinase | hexokinase | reperfusion injury salvage kinase | mitochondrial protein phosphatase 2C | IMM | PKC | PKG | amyloid beta | OMM | CsA | PP2Cm | receptor tyrosine kinases | G protein coupled receptors | ROS | ERK | permeability transition | ANT | PiC | SHP-1 | PTP | tumor necrosis factor receptor-associated protein 1 | Hsp90 | phosphate anion | GPCRs | protein phosphatase 2A | protein phosphatase 2B | reactive oxygen species | SH2-containing tyrosine phosphatase 1 | CyP-D | protein kinase G | heat shock protein 90 | protein kinase C | phosphate carrier | TRAP-1 | RISK | PP2A | RTKs | PINK1 | voltage-dependent anion channel | PP2B | VDAC | glycogen synthase kinase 3 | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Mitochondrial Membrane Transport Proteins - metabolism | Animals | Disease | Ion Channels - metabolism | Signal Transduction | Humans | Tyrosine | Phosphates | Synthesis | Phosphatases | Glycogen | Cytochrome P-450 | Heat shock proteins | Permeability | Protein kinases | Index Medicus
Journal Article
The FASEB journal, ISSN 0892-6638, 08/2017, Volume 31, Issue 8, pp. 3512 - 3526
intestinal epithelial cells | Shp‐1 | PI3K | β‐catenin | secretory cell fate | Secretory cell fate | B-catenin | Shp-1 | Intestinal epithelial cells | Humans | Intestines - growth & development | Gene Expression Regulation - physiology | Mice, Transgenic | Intestines - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Wnt Proteins - metabolism | Catenins - genetics | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - genetics | Colonic Neoplasms - metabolism | Mice, Knockout | Phosphatidylinositol 3-Kinases - genetics | Proto-Oncogene Proteins c-akt | Catenins - metabolism | Epithelial Cells - physiology | Animals | Wnt Proteins - genetics | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - metabolism | Mice | Intestines - cytology | TOR protein | Cell proliferation | Wnt protein | SHP-1 protein | Epithelial cells | Sox9 protein | Differentiation (biology) | Homology | AKT protein | Villus | Phosphatase | Small intestine | β-catenin | Perturbation methods | Intestine | Rodents | Tumorigenesis | Tyrosine | Rapamycin | Paneth cells | Cell differentiation | Src protein | Epithelium | 1-Phosphatidylinositol 3-kinase | Hemopoiesis | Signaling | Mucin | Stem cells | Tumor suppressor genes | Cell size | Tumors | Protein-tyrosine-phosphatase | Index Medicus
Journal Article