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Journal Article
Basic & Clinical Pharmacology & Toxicology, ISSN 1742-7835, 09/2011, Volume 109, Issue 3, pp. 164 - 174
Journal Article
Oral Diseases, ISSN 1354-523X, 07/2011, Volume 17, Issue 5, pp. 469 - 475
Oral Diseases (2011) 17, 469–475 Objectives:  The aim of this study was to evaluate the role of tolfenamic acid (Tol) and ampiroxicam (Amp) in the apoptotic... 
apoptosis | tolfenamic acid | myeloid cell leukemia‐1 | salivary mucoepidermoid carcinoma | Myeloid cell leukemia-1 | Salivary mucoepidermoid carcinoma | Tolfenamic acid | Apoptosis | ACTIVATION | MCL-1 | DOWN-REGULATION | HOMOHARRINGTONINE | BREAST-CANCER | IN-VITRO | REPRESSION | DENTISTRY, ORAL SURGERY & MEDICINE | GROWTH | myeloid cell leukemia-1 | DIFFERENTIATION | EXPRESSION | Immunohistochemistry | Extracellular Signal-Regulated MAP Kinases - pharmacology | RNA, Small Interfering - genetics | Nucleic Acid Synthesis Inhibitors - pharmacology | ortho-Aminobenzoates - pharmacology | Apoptosis - drug effects | Coloring Agents | Humans | G1 Phase - drug effects | Tetrazolium Salts | Transfection | Caspase 3 - drug effects | Thiazoles | Thiazines - pharmacology | Antineoplastic Agents - pharmacology | Indoles | Tumor Cells, Cultured | Sp1 Transcription Factor - pharmacology | JNK Mitogen-Activated Protein Kinases - pharmacology | Plicamycin - pharmacology | Reverse Transcriptase Polymerase Chain Reaction | p38 Mitogen-Activated Protein Kinases - pharmacology | Blotting, Western | Cyclooxygenase Inhibitors - pharmacology | Carcinoma, Mucoepidermoid - pathology | Myeloid Cell Leukemia Sequence 1 Protein | Proto-Oncogene Proteins c-bcl-2 - antagonists & inhibitors | Cell Proliferation - drug effects | Enzyme Activation | Cell Nucleus - drug effects | Salivary Gland Neoplasms - pathology | Messenger RNA | Carcinoma | Analysis | Toluene | Oncology, Experimental | DNA polymerases | Research | Cancer | Proteins | Cell growth | Kinases
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 06/2011, Volume 117, Issue 5, pp. 879 - 891
J. Neurochem. (2011) 117, 879–891. Dehydroepiandrosterone (DHEA) is one of the most abundant neurosteroids synthesized de novo in the CNS. We here found that... 
olfactory bulbectomized mice | extracellular signal‐regulated kinase | CaM kinase II | dehydroepiandrosterone | long‐term potentiation | protein kinase C | extracellular signal-regulated kinase | long-term potentiation | Extracellular signal-regulated kinase | Olfactory bulbectomized mice | Dehydroepiandrosterone | Protein kinase C | Long-term potentiation | ALZHEIMERS-DISEASE | IMMUNOHISTOCHEMICAL LOCALIZATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | SYNAPTIC PLASTICITY | NEUROSCIENCES | RAT HIPPOCAMPAL-NEURONS | GLUTAMATE RECEPTORS | AMPA RECEPTORS | CENTRAL-NERVOUS-SYSTEM | BINDING-SITES | METHYL-D-ASPARTATE | Phosphorylation | Dehydroepiandrosterone - antagonists & inhibitors | Anisoles - pharmacology | Male | Extracellular Signal-Regulated MAP Kinases - metabolism | Hippocampus - drug effects | Long-Term Potentiation - drug effects | Protein Kinase C - metabolism | Behavior, Animal - drug effects | CA1 Region, Hippocampal - metabolism | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - metabolism | Memory Disorders - psychology | Dehydroepiandrosterone - therapeutic use | Psychomotor Performance - drug effects | Receptors, sigma - agonists | Cognition Disorders - drug therapy | Enzyme Activation - drug effects | Blotting, Western | Hippocampus - metabolism | Animals | Maze Learning | Memory Disorders - drug therapy | Recognition (Psychology) - drug effects | Olfactory Bulb - physiology | Avoidance Learning - drug effects | Mice | Propylamines - pharmacology | Electrophysiological Phenomena | Proteins | Androgens | Protein kinases | Calmodulin | Computer-aided manufacturing | Neurology | Cognition & reasoning | Kinases | Memory | Steroids | Calcium | Neurosteroids | Glutamic acid receptors (ionotropic) | Central nervous system | Cognitive ability | N-Methyl-D-aspartic acid receptors | Glutamic acid receptors | Pattern recognition | Fear conditioning | Receptor mechanisms | Ca super(2+)/calmodulin-dependent protein kinase II | Hippocampus
Journal Article
Journal of Natural Products, ISSN 0163-3864, 08/2013, Volume 76, Issue 8, pp. 1413 - 1423
Journal Article
Journal Article
British Journal of Haematology, ISSN 0007-1048, 06/2011, Volume 153, Issue 5, pp. 545 - 556
Summary Chronic lymphocytic leukaemia (CLL) is the commonest haematological malignancy in the western world and is incurable by cytotoxic therapy. Considerable... 
chronic lymphocytic leukaemia drug sensitivity | apoptosis | chronic lymphocytic leukaemia | protein phosphorylation | trials | Chronic lymphocytic leukaemia drug sensitivity | Trials | Chronic lymphocytic leukaemia | Protein phosphorylation | Apoptosis | FACTOR-KAPPA-B | DRUG-RESISTANCE | DEPENDENT KINASE INHIBITOR | PHOSPHOINOSITIDE 3-KINASE | CANCER-THERAPY | CLL CELLS | PHASE-I TRIAL | FOSTAMATINIB DISODIUM | TRANSGENIC MOUSE MODEL | HEMATOLOGY | RECEPTOR TYROSINE KINASE | Apoptosis - drug effects | Protein-Tyrosine Kinases - metabolism | Humans | Enzyme Inhibitors - pharmacology | Intracellular Signaling Peptides and Proteins - metabolism | Leukemia, Lymphocytic, Chronic, B-Cell - pathology | Leukemia, Lymphocytic, Chronic, B-Cell - enzymology | src-Family Kinases - metabolism | Signal Transduction - physiology | Antineoplastic Agents - pharmacology | Apoptosis - physiology | Leukemia, Lymphocytic, Chronic, B-Cell - drug therapy | Enzyme Activation - physiology | Syk Kinase | Molecular Targeted Therapy - methods | Protein-Tyrosine Kinases - antagonists & inhibitors | Tyrosine | Medical colleges | Chemotherapy | Analysis | Health aspects | Protein kinases | Cancer | Index Medicus | Signal transduction | Animal models | Chronic lymphatic leukemia | Protein kinase C | Antibodies | Clinical trials | Extracellular signal-regulated kinase | AKT protein | Cytotoxicity | Malignancy | Protein-tyrosine kinase
Journal Article
Journal Article
Biochemistry, ISSN 0006-2960, 06/2015, Volume 54, Issue 22, pp. 3469 - 3482
Journal Article
European Journal of Neuroscience, ISSN 0953-816X, 06/2011, Volume 33, Issue 12, pp. 2288 - 2298
Striatal‐enriched protein tyrosine phosphatase (STEP) is a brain‐specific phosphatase that opposes synaptic strengthening by the regulation of key synaptic... 
ERK1/2 | STEP | synaptic plasticity | protein tyrosine phosphatase | glutamate receptors | Glutamate receptors | Protein tyrosine phosphatase | Synaptic plasticity | RECOGNITION | PHOSPHORYLATION | ALZHEIMERS-DISEASE | KINASE | MORRIS WATER MAZE | INDUCTION | NMDA RECEPTOR TRAFFICKING | ENDOCYTOSIS | NEUROSCIENCES | LONG-TERM POTENTIATION | Synaptic Transmission - physiology | Synaptic Transmission - genetics | Mice, Inbred C57BL | Receptors, N-Methyl-D-Aspartate - metabolism | Behavior, Animal - physiology | Protein Tyrosine Phosphatases, Non-Receptor - physiology | Mice, Knockout | Hippocampus - metabolism | Phosphorylation - genetics | Animals | Focal Adhesion Kinase 2 - metabolism | Mitogen-Activated Protein Kinase 3 - metabolism | Protein Tyrosine Phosphatases, Non-Receptor - genetics | Mice | Hippocampus - physiology | Mitogen-Activated Protein Kinase 1 | Receptors, AMPA - metabolism | Memory - physiology | Proteins | Tyrosine | Medical colleges | Neurosciences | Phosphatases | Phenols | Social aspects | Glutamate | alpha -Amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors | Phosphorylation | Glutamic acid receptors (ionotropic) | Memory | Cognitive ability | Extracellular signal-regulated kinase | Data processing | Dominance | N-Methyl-D-aspartic acid receptors | Glutamic acid receptors | Acuity | Learning | Social interactions | Motivation | Synaptic transmission | Sensorimotor integration | Protein-tyrosine kinase | Hippocampus | Protein-tyrosine-phosphatase | ERK1
Journal Article