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Journal Article
Journal Article
by Bailey, Matthew and Bailey, Matthew H and Tokheim, Collin and Porta-Pardo, Eduard and Sengupta, Sohini and Bertrand, Denis and Weerasinghe, Amila and Colaprico, Antonio and Wendl, Michael C and Kim, Jaegil and Reardon, Brendan and Ng, Kwok-Shing and Ng, Patrick Kwok-Shing and Jeong, Kang Jin and Cao, Song and Wang, Jioajiao and Wang, Timothy and Wang, Zhining and Wang, Zixing and Wang, Fang and Wang, Linghua and Wang, Jing and Wang, Min and Gao, Qingsong and Gao, Jianjiong and Gao, Galen F and Liu, Xiuping and Liu, Jia and Liu, Wenbin and Liu, Yuexin and Liu, Eric Minwei and Mularoni, Loris and Rubio-Perez, Carlota and Nagarajan, Niranjan and Cortés-Ciriano, Isidro and Zhou, Wanding and Zhou, Daniel Cui and Liang, Wen-Wei and Liang, Han and Hess, Julian M and Hess, Julian and Yellapantula, Venkata D and Tamborero, David and Gonzalez-Perez, Abel and Suphavilai, Chayaporn and Ko, Jia Yu and Khurana, Ekta and Park, Joong-Won and Park, Peter J and Van Allen, Eliezer M and Caesar-Johnson, Samantha J and Demchok, John A and Felau, Ina and Kasapi, Melpomeni and Ferguson, Martin L and Hutter, Carolyn M and Sofia, Heidi J and Tarnuzzer, Roy and Yang, Ju Dong and Yang, Hannah and Yang, Ian and Yang, Liming and Zenklusen, Jean C and Zhang, Wei and Zhang, Hongzheng and Zhang, Hailei and Zhang, Hongxin and Zhang, Jiexin and Zhang, Jiashan (Julia) and Zhang, Lizhi and Chudamani, Sudha and Lolla, Laxmi and Naresh, Rashi and Pihl, Todd and Sun, Qiang and Sun, Yichao and Wan, Yunhu and Wu, Ye and Cho, Juok and DeFreitas, Timothy and Frazer, Scott and Gehlenborg, Nils and Getz, Gad and Heiman, David I and Lawrence, Michael S and Lin, Pei and Meier, Sam and Noble, Michael S and Saksena, Gordon and Voet, Doug and Bernard, Brady and Chambwe, Nyasha and Dhankani, Varsha and Knijnenburg, Theo and Kramer, Roger and Leinonen, Kalle and Miller, Michael and Miller, Christopher A and Miller, Judy and Reynolds, Sheila and ... and Canc Genome Atlas Res Network and MC3 Working Grp and MC3 Working Group and Cancer Genome Atlas Research Network
Cell, ISSN 0092-8674, 04/2018, Volume 173, Issue 2, pp. 371 - 385.e18
Identifying molecular cancer drivers is critical for precision oncology. Multiple advanced algorithms to identify drivers now exist, but systematic attempts to... 
structure analysis | mutations of clinical relevance | oncology | driver gene discovery | MELANOMA | VARIANTS | SIGNATURES | LANDSCAPE | MICROSATELLITE INSTABILITY | PD-1 BLOCKADE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PATTERNS | OPEN-LABEL | SOMATIC MUTATIONS | DISCOVERY | CELL BIOLOGY | Oncology | driver discovery
Journal Article
PLoS Computational Biology, ISSN 1553-734X, 05/2015, Volume 11, Issue 5, p. e1004095
Horizontal or Lateral Gene Transfer (HGT or LGT) is the transmission of portions of genomic DNA between organisms through a process decoupled from vertical... 
SURROGATE METHODS | PATHOGENICITY ISLANDS | TRANSFER EVENTS | EVOLUTION | DNA-SEQUENCE | ESCHERICHIA-COLI | BDELLOVIBRIO-BACTERIOVORUS | BIOCHEMICAL RESEARCH METHODS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | GENOMIC SIGNATURE | THERMOTOGA-MARITIMA | INFERENCE | Trees | Evolution | Genes | Genomics
Journal Article
Science, ISSN 0036-8075, 9/2006, Volume 313, Issue 5795, pp. 1929 - 1935
To pursue a systematic approach to the discovery of functional connections among diseases, genetic perturbation, and drug action, we have created the first... 
Molecules | Databases | Disease models | Epithelial cells | Genes | Estrogens | Cell lines | Connectivity | Cultured cells | Research Articles | Signatures | CHAPERONE HEAT-SHOCK-PROTEIN-90 | IN-VITRO | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | ACUTE LYMPHOBLASTIC-LEUKEMIA | ESTROGEN | CELLULAR-DRUG RESISTANCE | TOXICITY | BREAST-CANCER-CELLS | INHIBITORS | MICROARRAY ANALYSIS | Estrogens - pharmacology | Gene Expression - drug effects | Oligonucleotide Array Sequence Analysis | Humans | Drug Resistance, Neoplasm | Gene Expression Profiling | Obesity - genetics | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Dexamethasone - pharmacology | Phenothiazines - pharmacology | Databases, Factual | Cell Line | Drug Evaluation, Preclinical - methods | Sirolimus - therapeutic use | Enzyme Inhibitors - pharmacology | Alzheimer Disease - drug therapy | Obesity - physiopathology | Sirolimus - pharmacology | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Precursor Cell Lymphoblastic Leukemia-Lymphoma - physiopathology | Limonins - pharmacology | Dexamethasone - therapeutic use | HSP90 Heat-Shock Proteins - antagonists & inhibitors | Cell Line, Tumor | Histone Deacetylase Inhibitors | Software | Alzheimer Disease - genetics | Drugs | Complications and side effects | Research | Genetic variation | Analysis | Diseases
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 20 - 11
Journal Article
Nature Communications, ISSN 2041-1723, 02/2014, Volume 5, Issue 1, pp. 3231 - 3231
Prognostic genes are key molecules informative for cancer prognosis and treatment. Previous studies have focused on the properties of individual prognostic... 
BREAST-CANCER | CELLS | MULTIDISCIPLINARY SCIENCES | GENOMIC ANALYSIS | ESSENTIALITY | EXPRESSION SIGNATURES | DISCOVERY | Neoplasms - metabolism | Prognosis | Neoplasms - genetics | Humans | Biomarkers, Tumor - metabolism | Biomarkers, Tumor - genetics | MicroRNAs - genetics | Neoplasms - diagnosis
Journal Article
Journal Article