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by Lu, SY and He, ZZ and Xu, JX and Yang, C and Chen, LJ and Gong, B
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ISSN 0146-0404, 07/2019, Volume 60, Issue 8, pp. 2914 - 2924
PURPOSE. To evaluate the association of single-nucleotide polymorphisms (SNPs) in the SIX1-SIX6 locus with primary open-angle glaucoma (POAG) through a... 
POAG | COMMON VARIANTS | RISK-FACTORS | meta-analysis | FIBER LAYER THICKNESS | SUSCEPTIBILITY LOCI | GENETIC-VARIANTS | MECHANISMS | IDENTIFICATION | SIX6 | SINE-OCULIS | OPHTHALMOLOGY | GENOME-WIDE ASSOCIATION
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2017, Volume 114, Issue 49, pp. E10540 - E10549
The development of CRISPR/Cas9 technologies has dramatically increased the accessibility and efficiency of genome editing in many organisms. In general, in... 
CRISPR | Aedes aegypti | Cas9 | Mutagenesis | Germline | ARBOVIRUS VECTOR | germline | YELLOW-FEVER MOSQUITO | DROSOPHILA-MELANOGASTER | GENE DRIVE | MULTIDISCIPLINARY SCIENCES | CRISPR-CAS9 | cas9 | mutagenesis | VESTIGIAL GENE | ELEMENT VECTOR | EVOLUTION | CRISPR/CAS9 SYSTEM | SINE OCULIS | Biological Sciences | PNAS Plus
Journal Article
Developmental biology, ISSN 0012-1606, 7/2016, Volume 415, Issue 1, pp. 157 - 167
Drosophila eye development is a complex process that involves many transcription factors (TFs) and interactions with their cofactors and targets. The TF Sine... 
Eye development | Transcription factor | RNA-Seq | Drosophila | Sine oculis | Eyes absent
Journal Article
by Yang, ZC and Qu, ZH and Yi, MJ and Shan, YC and Ran, N and Xu, L and Liu, XJ
JOURNAL OF CELLULAR PHYSIOLOGY, ISSN 0021-9541, 06/2019, Volume 234, Issue 6, pp. 8804 - 8814
MicroRNAs (miRNAs) are small yet versatile gene tuners that regulate a variety of cellular processes, including cell growth and proliferation. The aim of this... 
APOPTOSIS | CELLS | PHYSIOLOGY | airway remodeling | AIRWAY INFLAMMATION | asthma | MICRORNAS | CELL BIOLOGY | microRNA-448-5p | epithelial-mesenchymal transition (EMT) | EMERGING ROLE | PATHWAY | PROMOTES | Sine oculis homeobox homolog 1 (Six1)
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 12/2018, Volume 46, Issue 22, pp. 11743 - 11758
Abstract Eyeless (ey) is one of the most critical transcription factors for initiating the entire eye development in Drosophila. However, the molecular... 
PAIRED DOMAIN | ECTOPIC EYES | HOMEODOMAIN | PROTEIN | SINE-OCULIS | GENE | BIOCHEMISTRY & MOLECULAR BIOLOGY | TWIN-OF-EYELESS | HISTONE MODIFICATIONS | BINDING-SITES | TARGETED EXPRESSION | Gene regulation, Chromatin and Epigenetics
Journal Article
Trends in Neurosciences, ISSN 0166-2236, 2003, Volume 26, Issue 9, pp. 469 - 476
Journal Article
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 04/2019, Volume 129, pp. 58 - 68
The reduced expression of cardiac sarco-endoplasmic reticulum Ca ATPase (SERCA2a) is a hallmark of heart failure. We previously showed that miR-25 is a crucial... 
Heart failure | Six1 | Epigenetics | miRNA-25 | SERCA2a | PRC2 | CARDIAC & CARDIOVASCULAR SYSTEMS | CARDIAC DYSFUNCTION | EYES ABSENT GENE | CELL BIOLOGY | AAV1/SERCA2A | FAMILIES | DROSOPHILA SINE OCULIS | TARGETS | CLUSTER | EXPRESSION | EZH2 | Heart | Epigenetic inheritance | Medical colleges
Journal Article
Current Opinion in Genetics & Development, ISSN 0959-437X, 2015, Volume 32, pp. 37 - 46
Journal Article
Scientific Reports, ISSN 2045-2322, 03/2017, Volume 7, Issue 1, p. 44945
5D images of engrailed (en) and eye gone (eyg) gene expressions during the course of the eye-antenna disc primordium (EADP) formation of Drosophila embryos... 
HEAD | SINE-OCULIS | PATTERN | MULTIDISCIPLINARY SCIENCES | EYELESS GENE | VISUAL-SYSTEM | SPECIFICATION | BLASTODERM FATE MAP | MELANOGASTER | EXPRESSION | GONE | Eye | Insects | Microscopy | Embryos
Journal Article
DEVELOPMENTAL BIOLOGY, ISSN 0012-1606, 01/2017, Volume 421, Issue 2, pp. 171 - 182
Mutations in SIX1 and in its co-factor, EYA1, underlie Branchiootorenal Spectrum disorder (BOS), which is characterized by variable branchial arch, otic and... 
Plfap | DROSOPHILA VISUAL-SYSTEM | INNER-EAR | Eya1 | Branchiootorenal | SIX1 | DEVELOPMENTAL BIOLOGY | CELL FATE | BRANCHIOOTORENAL SYNDROME | XENOPUS-LAEVIS | SINE-OCULIS | CRANIAL PLACODES | ERBB-3 BINDING-PROTEIN | 6 FAMILY GENES | EYE DEVELOPMENT | Ebp1
Journal Article
PLoS Genetics, ISSN 1553-7390, 05/2014, Volume 10, Issue 5, p. e1004372
Journal Article
2008, Advances in Cancer Research, Volume 101, 34
The homeobox gene superfamily, encodes transcription factors that act as master regulators of development through their ability to activate or repress a... 
TRANSCRIPTION FACTORS | BRANCHIOOTORENAL BOR SYNDROME | SINE-OCULIS | ONCOLOGY | PHOSPHATASE-ACTIVITY | FREQUENT METHYLATION | EXTRASKELETAL MYXOID CHONDROSARCOMAS | CELL-CYCLE | FATE DETERMINATION FACTOR | EYES ABSENT | MYOTONIC-DYSTROPHY
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