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Behavioural Brain Research, ISSN 0166-4328, 2009, Volume 197, Issue 1, pp. 31 - 40
Journal Article
Journal Article
Neuroscience and Biobehavioral Reviews, ISSN 0149-7634, 2007, Volume 31, Issue 1, pp. 41 - 59
Journal Article
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, ISSN 0022-3565, 09/2004, Volume 310, Issue 3, pp. 952 - 963
The role of GABA(B) receptors in various behavioral processes has been largely defined using the prototypical GABA(B) receptor agonist baclofen. However,... 
SINGLY HOUSED MICE | ACID(B) RECEPTORS | INTERNATIONAL UNION | PHARMACOLOGICAL VALIDATION | ANXIETY | RATS | PROTEIN-COUPLED RECEPTORS | PHARMACOLOGY & PHARMACY | ANIMAL-MODEL | ALLOSTERIC MODULATION | STRESS-INDUCED HYPERTHERMIA
Journal Article
MedChemComm, ISSN 2040-2503, 11/2018, Volume 9, Issue 11, pp. 1882 - 1890
Close structural analogues of 5-carboxamidotryptamine (5-CT) based on the newly discovered indole–imidazole scaffold were synthesized and evaluated to search... 
Journal Article
MEDCHEMCOMM, ISSN 2040-2503, 11/2018, Volume 9, Issue 11, pp. 1882 - 1890
Close structural analogues of 5-carboxamidotryptamine (5-CT) based on the newly discovered indole-imidazole scaffold were synthesized and evaluated to search... 
SINGLY HOUSED MICE | CHEMISTRY, MEDICINAL | STIMULATION | CYTOCHROMES | RETT-SYNDROME | MEMORY | METABOLISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOLOGICAL EVALUATION | DRUG-LIKENESS | DERIVATIVES | STRESS-INDUCED HYPERTHERMIA
Journal Article
Psychopharmacology, ISSN 0033-3158, 7/2007, Volume 193, Issue 1, pp. 121 - 136
Data from both preclinical and clinical studies have provided proof of concept that modulation of limbic and forebrain glutamate, via mGlu2/3 receptor... 
Animal models | Biomedicine | mGlu2/3 receptor agonist | Schizophrenia | Antipsychotic | Anxiety | Pharmacology/Toxicology | Psychiatry | Psychiatric disorders | Anxiolytic | Metabotropic glutamate (mGlu) receptors | MGlu2/3 receptor agonist | SINGLY HOUSED MICE | animal models | METABOTROPIC GLUTAMATE-RECEPTOR | RAT | PSYCHIATRY | ACID LY354740 | schizophrenia | metabotropic glutamate (mGlu) receptors | NEUROSCIENCES | NUCLEUS-ACCUMBENS | PHENCYCLIDINE | anxiety | MESSENGER-RNA | MEDIAL PREFRONTAL CORTEX | PHARMACOLOGY & PHARMACY | antipsychotic | anxiolytic | psychiatric disorders | STRESS-INDUCED HYPERTHERMIA | Cyclic S-Oxides - chemistry | Phencyclidine - pharmacology | Rats, Inbred F344 | Motor Activity - drug effects | Male | Amino Acids - pharmacology | Diazepam - pharmacology | Dose-Response Relationship, Drug | Prefrontal Cortex - drug effects | Bridged Bicyclo Compounds, Heterocyclic - therapeutic use | Behavior, Animal - drug effects | Cyclic S-Oxides - pharmacology | Molecular Structure | Xanthenes - pharmacology | Disease Models, Animal | Bridged Bicyclo Compounds, Heterocyclic - chemistry | Amphetamine - pharmacology | Rats | Rats, Sprague-Dawley | Mental Disorders - psychology | Bridged Bicyclo Compounds, Heterocyclic - pharmacology | Cyclic S-Oxides - therapeutic use | Animals | Mental Disorders - drug therapy | Prefrontal Cortex - metabolism | Mice | Receptors, Metabotropic Glutamate - agonists | Receptors, Metabotropic Glutamate - antagonists & inhibitors | Neurology | Brain | Pharmacology | Psychology | Rodents
Journal Article
Neuropsychopharmacology, ISSN 0893-133X, 06/2006, Volume 31, Issue 6, pp. 1135 - 1145
Repeated exposure to stressful conditions is linked to the etiology of affective disorders. The melanin-concentrating hormone-1 receptor (MCHR1) may be a novel... 
Anxiety | Microdialysis | Prefrontal cortex | Melanin-concentrating hormone | Stress | stress | SINGLY HOUSED MICE | PSYCHOLOGICAL STRESS | PSYCHIATRY | prefrontal cortex | INDUCED HYPERTHERMIA | ACETYLCHOLINE-RELEASE | melanin-concentrating hormone | NEUROSCIENCES | NUCLEUS-ACCUMBENS | anxiety | MCH | microdialysis | PITUITARY | PHARMACOLOGY & PHARMACY | RAT-BRAIN | PLUS-MAZE | Brain Chemistry - drug effects | Body Temperature - drug effects | Male | Acetylcholine - metabolism | Dose-Response Relationship, Drug | Stress, Physiological - metabolism | Neurosecretory Systems - metabolism | Behavior, Animal - drug effects | Receptors, Somatostatin - antagonists & inhibitors | Receptors, Somatostatin - physiology | Alprazolam - pharmacology | Corticosterone - blood | Adrenocorticotropic Hormone - blood | Melanins - administration & dosage | Maze Learning - physiology | Mice, Inbred C57BL | Hypothalamic Hormones - administration & dosage | Pituitary Hormones - administration & dosage | Anti-Anxiety Agents - pharmacology | Behavior, Animal - physiology | Stress, Physiological - physiopathology | Random Allocation | Maze Learning - drug effects | Receptors, Somatostatin - deficiency | Brain Chemistry - physiology | Mice, Knockout | Animals | Neurosecretory Systems - drug effects | Mice | Stress, Physiological - psychology
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 2003, Volume 463, Issue 1, pp. 117 - 132
Journal Article
Physiology & Behavior, ISSN 0031-9384, 2009, Volume 98, Issue 1, pp. 37 - 43
Journal Article
Psychopharmacology, ISSN 0033-3158, 6/2013, Volume 227, Issue 4, pp. 711 - 725
Several studies have suggested that modulation of the glutamatergic system via metabotropic glutamate receptors (mGlu) could be a new way to achieve... 
Animal model | Neurosciences | Schizophrenia |