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BBA - Molecular and Cell Biology of Lipids, ISSN 1388-1981, 05/2017, Volume 1862, Issue 5, pp. 541 - 551
Journal Article
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 10/2013, Volume 272, Issue 2, pp. 299 - 305
Journal Article
Journal Article
Toxicological Sciences, ISSN 1096-6080, 05/2018, Volume 163, Issue 1, pp. 254 - 264
Abstract Although detailed pathophysiological mechanisms of fulminant hepatitis remain elusive, immune cell recruitment with excessive cytokine production is a... 
Chemokine | Inflammation | Liver injury | Small heterodimer partner | NUCLEAR RECEPTOR SHP | chemokine | liver injury | ACTIVATION | IMMUNE CELLS | A-INDUCED HEPATITIS | MECHANISMS | CXC CHEMOKINES | INTERLEUKIN-10 | CONCANAVALIN-A | DISEASES | inflammation | small heterodimer partner | TOXICOLOGY | EXPRESSION
Journal Article
Diabetologia, ISSN 0012-186X, 5/2012, Volume 55, Issue 5, pp. 1482 - 1494
IL-6 is a proinflammatory cytokine associated with the pathogenesis of hepatic diseases. Metformin is an anti-diabetic drug used for the treatment of type 2... 
Nr0b2 | Medicine & Public Health | Human Physiology | Insulin sensitivity | Metabolic Diseases | Internal Medicine | Insulin resistance | Shp | Metformin | AMP-activated protein kinase | Interleukin-6 | Small heterodimer partner | SUPPRESSOR | CELLS | METABOLIC SYNDROME | HEPATOCYTES | ACTIVATED PROTEIN-KINASE | FATTY LIVER-DISEASE | SOCS-3 | DEFICIENT MICE | IN-VIVO | ENDOCRINOLOGY & METABOLISM | Hypoglycemic Agents - therapeutic use | Promoter Regions, Genetic | AMP-Activated Protein Kinases - metabolism | Metformin - therapeutic use | Liver - metabolism | Insulin Resistance | Suppressor of Cytokine Signaling Proteins - genetics | Receptors, Cytoplasmic and Nuclear - biosynthesis | Orphan Nuclear Receptors - biosynthesis | Suppressor of Cytokine Signaling 3 Protein | Insulin - metabolism | Animals | Liver - drug effects | Mice | Suppressor of Cytokine Signaling Proteins - metabolism | Interleukin-6 - metabolism | STAT3 Transcription Factor - metabolism | Type 2 diabetes | Anopheles | Chromatin | Interleukins | DNA | Genes | Hypoglycemic agents | Diabetes | Protein kinases | DNA-ligand interactions | Animal models | Immunoprecipitation | Liver diseases | Transcription | Diabetes mellitus | Liver | Stat3 protein | Homeostasis | Inflammation | Insulin | Nuclei | Promoters | Interleukin 6 | Signal transduction | SOCS-3 protein | Gluconeogenesis | orphan nuclear receptors
Journal Article
Diabetes, ISSN 0012-1797, 02/2008, Volume 57, Issue 2, pp. 306 - 314
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2014, Volume 9, Issue 1, p. e86553
The farnesoid X receptor (FXR) is mainly expressed in liver, intestine and kidney. We investigated whether 6-ethyl chenodeoxycholic acid (6ECDCA), a... 
ACID | INHIBITION | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | RATS | CELL APOPTOSIS | KAPPA-B | IDENTIFICATION | RENAL INTERSTITIAL FIBROSIS | TERMINAL KINASE | NUCLEAR RECEPTOR | In Situ Nick-End Labeling | RNA, Small Interfering - genetics | Mice, Inbred C57BL | Transforming Growth Factor beta1 - metabolism | Epithelial-Mesenchymal Transition - drug effects | Immunoblotting | Male | DNA Primers - genetics | Acute Kidney Injury - prevention & control | Chenodeoxycholic Acid - analogs & derivatives | Immunoenzyme Techniques | Animals | Analysis of Variance | RNA Interference | Signal Transduction - drug effects | Chenodeoxycholic Acid - metabolism | Chenodeoxycholic Acid - pharmacology | Cisplatin - adverse effects | Acute Kidney Injury - chemically induced | Mice | Real-Time Polymerase Chain Reaction | Receptors, Cytoplasmic and Nuclear - metabolism | Bone morphogenetic proteins | RNA | Transforming growth factors | Cisplatin | Deoxycholic acid | Transcription factors | Smad protein | Bax protein | Bcl-2 protein | Mesenchyme | Syngeneic grafts | Liver | Transforming growth factor | Activation | Kinases | Medical schools | Proteins | Signal transduction | Cell activation | Obstructions | Intestine | Rodents | Attenuation | Physiology | Inhibition | Pretreatment | NF-κB protein | Kidneys | Cytokines | Internal medicine | Markers | Casts | JNK protein | Inflammation | siRNA | Gene expression | Ribonucleic acid--RNA | Medicine | Polymerase chain reaction | Signaling | Injury prevention | Fibrosis | Ligands | Kidney diseases | Diabetes | Chenodeoxycholic acid | Apoptosis | Kidney transplantation | Bile | Ribonucleic acid
Journal Article
Journal Article
Molecular Nutrition & Food Research, ISSN 1613-4125, 10/2008, Volume 52, Issue 10, pp. 1172 - 1181
Journal Article