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Arteriosclerosis thrombosis and vascular biology, ISSN 1079-5642, 01/2013, Volume 33, Issue 1, pp. 67 - +
Objective-Aldosterone (Aldo) is involved in arterial stiffness and heart failure, but the mechanisms have remained unclear. Galectin-3 (Gal-3), a... 
collagen type I | fibrosis | galectin-3 | vascular smooth muscle cells | aldosterone | HEART-FAILURE | LEFT-VENTRICULAR DYSFUNCTION | INFLAMMATION | ENDOTHELIAL-CELLS | PERIPHERAL VASCULAR DISEASE | SMOOTH-MUSCLE-CELLS | EXTRACELLULAR-MATRIX | MICE | HEMATOLOGY | EXPRESSION | INSIGHTS | CARDIOTROPHIN-1 | Blood Pressure | Inflammation - chemically induced | Inflammation - pathology | Up-Regulation | Muscle, Smooth, Vascular - metabolism | Rats, Wistar | Humans | Galectin 3 - metabolism | Myocytes, Smooth Muscle - pathology | Male | Aldosterone | Muscle, Smooth, Vascular - physiopathology | Galectin 3 - deficiency | Inflammation - metabolism | Transfection | RNA Interference | Time Factors | Hypertension - chemically induced | Mineralocorticoid Receptor Antagonists - pharmacology | Hypertension - prevention & control | Hypertension - genetics | Myocytes, Smooth Muscle - drug effects | Vascular Stiffness | Myocytes, Smooth Muscle - metabolism | Disease Models, Animal | Muscle, Smooth, Vascular - drug effects | Mice, Inbred C57BL | Cells, Cultured | Rats | Galectin 3 - genetics | Hypertension - pathology | Hypertension - physiopathology | Hypertension - metabolism | Mice, Knockout | Collagen Type I - biosynthesis | Muscle, Smooth, Vascular - pathology | Animals | Galectin 3 - antagonists & inhibitors | Fibrosis | Inflammation - genetics | Inflammation - prevention & control | Mice | Inflammation - physiopathology | Cellular Biology | Life Sciences | Muscle, Smooth, Vascular | Mineralocorticoid Receptor Antagonists | Hypertension | Hematology | Biochemistry, Molecular Biology | Collagen Type I | Inflammation | Human health and pathology | Myocytes, Smooth Muscle | Galectin 3
Journal Article
Journal of smooth muscle research, ISSN 0916-8737, 1991
Journal
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2015, Volume 136, Issue 3, pp. 769 - 780
Background Inflammation and oxidative stress play critical roles in patients with chronic obstructive pulmonary disease (COPD). Mitochondrial oxidative stress... 
Allergy and Immunology | airway hyperresponsiveness | antioxidant | proliferation | MitoQ | inflammation | mitochondria | airway smooth muscle | Ozone | oxidative stress | chronic obstructive pulmonary disease | ASTHMA FEATURES | MECHANISMS | IMMUNOLOGY | FRAGMENTATION | HYPERRESPONSIVENESS | BETA | RESPONSES | ALLERGY | ENERGY-METABOLISM | EXPRESSION | COPD | Respiratory System - pathology | Reactive Oxygen Species - metabolism | Humans | Middle Aged | Male | Pulmonary Disease, Chronic Obstructive - pathology | Bronchial Hyperreactivity - genetics | Ubiquinone - pharmacology | Muscle, Smooth - drug effects | Smoking - physiopathology | Organophosphorus Compounds - pharmacology | Myocytes, Smooth Muscle - drug effects | Pneumonia - genetics | Pulmonary Disease, Chronic Obstructive - genetics | Bronchial Hyperreactivity - chemically induced | Signal Transduction | Mitochondria - pathology | Smoking - metabolism | Bronchial Hyperreactivity - pathology | Reactive Oxygen Species - antagonists & inhibitors | Electron Transport Chain Complex Proteins - metabolism | Pulmonary Disease, Chronic Obstructive - chemically induced | Respiratory System - drug effects | Airway Remodeling - genetics | Mice | Oxidative Stress - drug effects | Bronchial Hyperreactivity - drug therapy | Myocytes, Smooth Muscle - pathology | Pneumonia - pathology | Membrane Potential, Mitochondrial - drug effects | Pneumonia - chemically induced | Adult | Female | Pulmonary Disease, Chronic Obstructive - metabolism | Myocytes, Smooth Muscle - metabolism | Ubiquinone - analogs & derivatives | Gene Expression Regulation | Hydrogen Peroxide - pharmacology | Electron Transport Chain Complex Proteins - genetics | Mitochondria - metabolism | Antioxidants - pharmacology | Mitochondria - drug effects | Muscle, Smooth - metabolism | Animals | Pneumonia - drug therapy | Respiratory System - metabolism | Aged | Muscle, Smooth - pathology | Oxidative stress | Care and treatment | Lung diseases, Obstructive | Inflammation | Pharmaceutical industry | Biomedical research | Disease | Laboratories | Mortality | Colleges & universities | Smooth muscle | Mitochondrial DNA | Metabolism | Defects | Antioxidants | Mitochondria | Hospitals | Biopsy | Chronic obstructive pulmonary disease | Apoptosis | Smoking | NO, Nitric oxide | ΔΨm, Mitochondrial membrane potential | ASM, Airway smooth muscle | NAC, N-acetylcysteine | RL, Lung resistance | BAL, Bronchoalveolar lavage | OCR, Oxygen consumption rate | dTPP, Decyltriphenylphosphonium bromide | AHR, Airway hyperresponsiveness | logPC100, Concentration of acetylcholine that increased lung resistance by 100 | GOLD, Global Initiative for Chronic Obstructive Lung Disease | ATP, Adenosine triphosphate | KC, Keratinocyte-derived cytokine | JC-1, 5,5′,6,6′-Tetrachloro-1,1′,3,3′-tetraethylbenzimidazolylcarbocyanine iodide | COPD, Chronic obstructive pulmonary disease | ROS, Reactive oxygen species | Mechanisms of Allergy and Clinical Immunology
Journal Article
Nature Cell Biology, ISSN 1465-7392, 08/2015, Volume 17, Issue 8, pp. 994 - 1003
The use of human pluripotent stem cells for in vitro disease modelling and clinical applications requires protocols that convert these cells into relevant... 
DERIVATION | DIRECTED DIFFERENTIATION | IN-VITRO | GENE | FUNCTIONALITY | GROWTH | DEFINITIVE ENDODERM | RECEPTOR | WNT | LINES | CELL BIOLOGY | Coculture Techniques | Humans | Endothelial Cells - transplantation | Glycogen Synthase Kinase 3 beta | Cell Lineage - drug effects | Dose-Response Relationship, Drug | Human Umbilical Vein Endothelial Cells - physiology | Transfection | Time Factors | Gene Expression Regulation, Developmental | Transcription, Genetic | Myocytes, Smooth Muscle - drug effects | Proto-Oncogene Proteins c-sis - pharmacology | Myocytes, Smooth Muscle - transplantation | Vascular Endothelial Growth Factor A - pharmacology | Endothelial Cells - physiology | Muscle, Smooth, Vascular - physiology | Muscle, Smooth, Vascular - drug effects | Biomarkers - metabolism | Cell Line | Induced Pluripotent Stem Cells - enzymology | Induced Pluripotent Stem Cells - drug effects | Induced Pluripotent Stem Cells - physiology | Glycogen Synthase Kinase 3 - antagonists & inhibitors | Myocytes, Smooth Muscle - enzymology | Induced Pluripotent Stem Cells - transplantation | Myocytes, Smooth Muscle - physiology | Gene Expression Profiling - methods | Muscle, Smooth, Vascular - transplantation | Glycogen Synthase Kinase 3 - metabolism | Mice, SCID | Muscle, Smooth, Vascular - cytology | Metabolomics - methods | Bone Morphogenetic Protein 4 - pharmacology | Phenotype | Animals | Wnt Signaling Pathway - drug effects | Cell Differentiation - drug effects | Mice, Inbred NOD | Protein Kinase Inhibitors - pharmacology | Endothelial Cells - enzymology | Muscle, Smooth, Vascular - enzymology | Neovascularization, Physiologic | Endothelial Cells - drug effects | Usage | Cell research | Growth | Stem cells | Muscle cells | Research | Cell differentiation | Endothelium
Journal Article
1994, Handbook of experimental pharmacology, ISBN 9780387578880, Volume 111., xxiv, 727
Book
Journal of Vascular Surgery, ISSN 0741-5214, 2015, Volume 64, Issue 5, pp. 1444 - 1449
Journal Article
Pharmacology and Therapeutics, ISSN 0163-7258, 09/2016, Volume 165, pp. 14 - 25
Smooth muscle cells provide crucial contractile functions in visceral, vascular, and lung tissues. The contractile state of smooth muscle is largely determined... 
Kv7 channel | Visceral smooth muscle | KCNQ | Vascular smooth muscle | Voltage-gated potassium channel | Airway smooth muscle | DRUG-THERAPY | KCNE-BETA-SUBUNITS | CHROMANOL 293B | DOWN-REGULATION | K(V)7 CHANNELS | FUNCTIONAL-CHARACTERIZATION | I-KS | RETIGABINE EZOGABINE | RECTIFIER K+ CURRENT | PHARMACOLOGY & PHARMACY | CEREBRAL VASOSPASM | Bronchodilator Agents - therapeutic use | Muscle, Smooth, Vascular - metabolism | Humans | Potassium Channel Blockers - therapeutic use | Molecular Targeted Therapy | Bronchoconstrictor Agents - therapeutic use | Muscle, Smooth, Vascular - physiopathology | Potassium Channel Blockers - adverse effects | KCNQ Potassium Channels - antagonists & inhibitors | Muscle, Smooth - drug effects | Bronchoconstriction - drug effects | Drug Design | Viscera - physiopathology | Muscle, Smooth, Vascular - drug effects | Vasoconstrictor Agents - pharmacology | Viscera - metabolism | Vasodilator Agents - pharmacology | KCNQ Potassium Channels - agonists | Viscera - drug effects | Muscle, Smooth - metabolism | Vasoconstriction - drug effects | Animals | Signal Transduction - drug effects | KCNQ Potassium Channels - metabolism | Respiratory System - metabolism | Muscle, Smooth - physiopathology | Respiratory System - drug effects | Respiratory System - physiopathology | Vasodilation - drug effects | Smooth muscle | Potassium channels
Journal Article
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 02/2014, Volume 34, Issue 2, pp. 355 - 364
OBJECTIVE—Vascular remodeling occurs after endothelial injury, resulting in smooth muscle cell (SMC) proliferation and vascular fibrosis. We previously... 
placental growth factor | receptors mineralocorticoid | vascular endothelial growth factor receptor-1 | aldosterone | myocytes smooth muscle | MORTALITY | OXIDATIVE STRESS | EVENTS | receptors | smooth muscle | myocytes | mineralocorticoid | BLOOD-PRESSURE | SPIRONOLACTONE | PERIPHERAL VASCULAR DISEASE | EPLERENONE | HYPERTENSION | HEMATOLOGY | EXPRESSION | BLOCKER | GENE-TRANSCRIPTION | Carotid Arteries - drug effects | Carotid Arteries - metabolism | Receptors, Mineralocorticoid - agonists | Receptors, Mineralocorticoid - genetics | Vascular Endothelial Growth Factor Receptor-1 - antagonists & inhibitors | Muscle, Smooth, Vascular - metabolism | Pregnancy Proteins - genetics | Myocytes, Smooth Muscle - pathology | Male | Pregnancy Proteins - metabolism | RNA, Messenger - metabolism | Receptors, Mineralocorticoid - deficiency | Time Factors | Carotid Artery Injuries - genetics | Myocytes, Smooth Muscle - drug effects | Myocytes, Smooth Muscle - metabolism | Carotid Artery Injuries - metabolism | Carotid Artery Injuries - pathology | Disease Models, Animal | Muscle, Smooth, Vascular - drug effects | Endothelial Cells - metabolism | Mice, Inbred C57BL | Aldosterone - pharmacology | Vascular Endothelial Growth Factor Receptor-1 - metabolism | Mice, Knockout | Antibodies - pharmacology | Muscle, Smooth, Vascular - pathology | Animals | Fibrosis | Placenta Growth Factor | Carotid Arteries - pathology | Cell Proliferation - drug effects | Mice | Endothelial Cells - pathology | Endothelial Cells - drug effects | smooth muscle cells | mineralocorticoid receptor | vascular remodeling | VEGF
Journal Article
Journal Article
Circulation, ISSN 0009-7322, 05/2010, Volume 121, Issue 20, pp. 2200 - 2210
Journal Article