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Cancer Biology & Therapy, ISSN 1538-4047, 06/2019, Volume 20, Issue 6, pp. 922 - 930
Ceramide synthase 6 (CerS6) is an enzyme that preferentially generates pro-apoptotic C 16 -ceramide in the sphingolipid metabolic pathway. Reduced expression... 
ceramide synthase | ceramide nanoliposome | SNAI2
Journal Article
Genes and Cancer, ISSN 1947-6019, 08/2011, Volume 2, Issue 8, pp. 782 - 791
It has become increasingly clear that microRNAs (miRNAs) play important roles in tumorigenesis and metastasis. Recently, miR-203 was reported as a suppressor... 
migration | breast cancer | SNAI2 | miR-203 | invasion | Original
Journal Article
BBA - Molecular Basis of Disease, ISSN 0925-4439, 03/2020, Volume 1866, Issue 3, p. 165644
Neuroblastoma is the most common extracranial solid tumor in children and originates from poorly differentiated neural crest progenitors. High-risk... 
SNAI2 | Neuroblastoma | Metastasis | Differentiation | Retinoic acid
Journal Article
IUBMB LIFE, ISSN 1521-6543, 03/2018, Volume 70, Issue 3, pp. 224 - 236
Dysregulation of microRNA expression plays a pivotal role in the initiation and progression of a variety of human carcinomas including prostate cancer. Our... 
METASTASIS | CANCER CELLS | angiogenesis | CATENIN signal pathway | BIOCHEMISTRY & MOLECULAR BIOLOGY | cancer stemness | DOWN-REGULATION | GSK-3 | E-CADHERIN | BETA-CATENIN | SNAI2 axis | SLUG | CELL BIOLOGY | EPITHELIAL-MESENCHYMAL TRANSITION | prostate cancer | SNAI2 | MiR-203 | DIFFERENTIATION | EXPRESSION | Development and progression | Metastasis | Prostate cancer | Analysis
Journal Article
Oncogene, ISSN 0950-9232, 9/2015, Volume 34, Issue 36, pp. 4777 - 4790
Breast cancer is a major cause of mortality in women. The transcription factor SNAI2 has been implicated in the pathogenesis of several types of cancer,... 
SNAI2 | post-lactational involution | ERBB2 | Luminal breast cancer
Journal Article
Journal of Cancer, ISSN 1837-9664, 2019, Volume 10, Issue 11, pp. 2480 - 2487
: Recently, accumulating evidence has indicated that the 3' untranslated regions (3'UTRs) of protein coding genes play critical roles in the progression of... 
Journal Article
by Zhu, P and Zhang, CP and Gao, YX and Wu, FR and Zhou, YL and Wu, WS
NATURE COMMUNICATIONS, ISSN 2041-1723, 06/2019, Volume 10
Activation of the p16(Ink4a )associated senescence pathway during aging breaks muscle homeostasis and causes degenerative muscle disease by irreversibly... 
SKELETAL-MUSCLE | ACTIVATION | REJUVENATION | PATHWAY | REGENERATION | MULTIDISCIPLINARY SCIENCES | SELF-RENEWAL | SNAI2 EXPRESSION | SATELLITE CELLS | STRENGTH | DIFFERENTIATION
Journal Article
Oncotarget, ISSN 1949-2553, 2015, Volume 6, Issue 11, pp. 8760 - 8776
Neuroblastoma is an embryonal tumor derived from poorly differentiated neural crest cells. Current research is aimed at identifying the molecular mechanisms... 
neuroblastoma | Trpm7 | Oncology | Snai2 | Metastasis | Differentiation
Journal Article
Biology of Reproduction, ISSN 0006-3363, 05/2019, Volume 100, Issue 5, pp. 1171 - 1179
Abstract Objective To study the potential role of miR-30a-3p in embryo implantation and explore underlying mechanisms. Methods We first established normal... 
MIR-30A-3P | CELLS | microRNA-30a-3p | ENDOMETRIUM | DOWN-REGULATION | Snai2 | CANCER | SIGNATURE | EMT | embryo implantation | FAMILY | REPRODUCTIVE BIOLOGY | MIR-30C-2-3P | epithelial-mesenchymal transition | EXPRESSION
Journal Article
by Ma, X and Li, L and Jia, T and Chen, MW and Liu, GF and Li, CY and Li, N and Yang, DP
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ISSN 0006-291X, 09/2017, Volume 491, Issue 2, pp. 241 - 249
Keratinocyte differentiation plays a pivotal role in the function of epidermal barrier and can be triggered by extracellular calcium in vitro and in vivo, but... 
CELLS | BIOPHYSICS | Delta Np63 | BIOCHEMISTRY & MOLECULAR BIOLOGY | GROWTH | HACAT | Keratinocyte | SNAI2 | Epidermal differentiation | INHIBITS PROLIFERATION | EXPRESSION | miR-203a
Journal Article
JOURNAL OF CELLULAR PHYSIOLOGY, ISSN 0021-9541, 07/2019, Volume 234, Issue 7, pp. 11474 - 11489
Junctional epithelium (JE) demonstrates biological responses with the rapid turnover of gingival epithelial cells. The state occurs in inflammation of gingiva... 
junctional epithelium | SMAD2 | LOCALIZATION | APOPTOSIS | PHYSIOLOGY | PROTEIN | amelotin | PROINFLAMMATORY CYTOKINES | CELL BIOLOGY | CELL PLASTICITY | SNAI2 | epithelial-mesenchymal transition | EXPRESSION PATTERN | PROMOTER | TGF-BETA-1
Journal Article
OncoImmunology, ISSN 2162-4011, 01/2017, Volume 6, Issue 1, p. e1263412
PD-L1 expression and regulation by mesenchymal tumor cells remain largely undefined. Here, we report that among different EMT-activated MCF7 human breast... 
PD-L1 | SLUG (SNAI2) | SNAI1 | Breast cancer | miR-200 and immunotherapy | epithelial-to-mesenchymal transition | ZEB-1 | Epithelial-tomesenchymal transition | MiR-200 and immunotherapy | SAFETY | miR-200 and | SUSCEPTIBILITY | LYSIS | ANTIBODY | AUTOPHAGY | IMMUNOLOGY | ESCAPE | ONCOLOGY | immunotherapy | EXPRESSION
Journal Article
BBA - General Subjects, ISSN 0304-4165, 11/2013, Volume 1830, Issue 11, pp. 5258 - 5266
To date microRNAs and their contribution to the onset and propagation of salivary adenoid cystic carcinoma (SACC) are limited. The objective of this study was... 
MiR-181a | Snai2 | MicroRNA | Metastasis | Salivary adenoid cystic carcinoma | MAPK | FAMILY-MEMBERS | BIOCHEMISTRY & MOLECULAR BIOLOGY | SLUG | SIGNATURE | RADIATION | TRANSITION | INVASION | BIOPHYSICS | PROMOTES MIGRATION | SQUAMOUS-CELL CARCINOMA | EXPRESSION | HUMAN CANCER | Carcinoma | Cancer
Journal Article
CANCER BIOLOGY & THERAPY, ISSN 1538-4047, 06/2019, Volume 20, Issue 6, pp. 922 - 930
Ceramide synthase 6 (CerS6) is an enzyme that preferentially generates pro-apoptotic C-16-ceramide in the sphingolipid metabolic pathway. Reduced expression of... 
CERAMIDE SYNTHASE 6 | ceramide synthase | DOWN-REGULATION | ceramide nanoliposome | SLUG | PRE-MESSENGER-RNA | NANOLIPOSOMES | ONCOLOGY | POOR SURVIVAL | BCL-X | SNAI2 | PROMOTER | CASPASE-9 | BINDING
Journal Article
Oncology Reports, ISSN 1021-335X, 04/2018, Volume 39, Issue 4, pp. 1874 - 1882
Dormant tumor cells (DTCs) serve a crucial role in the pathogenesis of metastasis and may compromise the efficacy of existing therapeutic modalities aimed at... 
DTCs | SNAI2 | Transdifferentiation | AEC | Dormant-Toproliferating switch
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 07/2019, Volume 234, Issue 7, pp. 11474 - 11489
Junctional epithelium (JE) demonstrates biological responses with the rapid turnover of gingival epithelial cells. The state occurs in inflammation of gingiva... 
junctional epithelium | epithelial–mesenchymal transition | SNAI2 | amelotin | Periodontics | Wound healing | Transcription | Mesenchyme | Cytokines | Epithelial cells | Homeostasis | Smad3 protein | Inflammation | siRNA | Gene expression | Epithelium | Ribonucleic acid--RNA | Signal transduction | Signaling | Negative feedback | Feedback | Fibrosis | Gingiva | Snail protein | Growth factors | Apoptosis
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 03/2012, Volume 287, Issue 13, pp. 9962 - 9971
Journal Article