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Angewandte Chemie International Edition, ISSN 1433-7851, 09/2011, Volume 50, Issue 39, pp. 9124 - 9127
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 01/2017, Volume 58, Issue 2, pp. 121 - 124
[Display omitted] •A four component has been used to synthesis imidazo[1,2-a]pyridines.•The mechanism relies on sequential reductive amination, condensation,... 
Reductive amination | Copper-catalyzed | Sodium azide | 2-Bromopyridine | Aldehyde | Isocyanide | Imidazo[1,2-a]pyridine | ONE-POT SYNTHESIS | ALPIDEM | CHEMISTRY, ORGANIC | SNAR | 2-AMINOPYRIDINES | ZOLPIDEM | AFFINITY | MULTICOMPONENT SYNTHESIS | INHIBITORS | DERIVATIVES | BINDING | Copper | Pyridine
Journal Article
The Journal of Organic Chemistry, ISSN 0022-3263, 05/2011, Volume 76, Issue 9, pp. 3174 - 3180
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 08/2011, Volume 52, Issue 32, pp. 4149 - 4152
BOP efficiently promoted the phosphonium-mediated cyclization of thioureas, leading to a convenient synthesis of 2-aminobenzimidazoles. Compared to... 
Thioureas | Phosphonium-mediated cyclization | 2-Aminobenzimidazoles | MEBENDAZOLE | CHEMISTRY, ORGANIC | INHIBITOR CLINICAL CANDIDATE | SNAR REACTIONS | POTENT | HETEROCYCLES | THIO-COMPOUNDS | BENZIMIDAZOLES | CYCLODESULFURIZATION | ANTAGONISTS | DERIVATIVES | Tetrahedrons | Synthesis (chemistry) | Methodology
Journal Article
Synlett, ISSN 0936-5214, 08/2013, Volume 24, Issue 13, pp. 1687 - 1692
Abstract A new, highly efficient procedure for the synthesis of benzothiophenes from easily available o -halovinylbenzenes and potassium sulfide has been... 
letter | dehydrogenation process | Ar-type reaction | benzo[b]thiophenes | direct S | transition-metal-free | o-halo-vinylbenzenes | cyclization | ELECTROPHILIC CYCLIZATION | ONE-POT SYNTHESIS | direct SNAr-type reaction | EFFICIENT SYNTHESIS | BENZOTHIOPHENES | CHEMISTRY, ORGANIC | FACILE SYNTHESIS | INHIBITORS | THIOPHENES | o-halovinylbenzenes | DERIVATIVES
Journal Article
Heterocyclic Communications, ISSN 0793-0283, 08/2018, Volume 24, Issue 4, pp. 219 - 230
Journal Article
Chinese Journal of Organic Chemistry, ISSN 0253-2786, 06/2016, Volume 36, Issue 6, pp. 1241 - 1265
Journal Article
Synthesis, ISSN 0039-7881, 03/2019, Volume 51, Issue 5, pp. 1139 - 1156
Abstract A general synthetic approach to rotenoids is described, featuring 1) stereospecific, group-selective 1,2-rearrangements of epoxy alcohols, and 2) S N... 
feature | rotenoid | CHEMISTRY, ORGANIC | IDENTIFICATION | CONSTITUTION | DEGUELIN | PINACOL-TYPE REARRANGEMENT | semi-pinacol rearrangement | INSECT TOXINS | isoflavonoid | (+/-)-DEGUELIN | ISOFLAVONOIDS | SNAr cyclization | TRIETHYLALUMINUM | total synthesis | ASYMMETRIC TOTAL-SYNTHESIS | CONCISE SYNTHESIS
Journal Article
Asian Journal of Organic Chemistry, ISSN 2193-5807, 05/2016, Volume 5, Issue 5, pp. 699 - 704
An efficient method was developed for the synthesis of 1‐naphthols through NaOtBu‐promoted SNAr reaction of ortho‐haloacetophenones followed by Lewis acid... 
copper catalysis | ortho-haloacetophenones | aryl halides | SNAr reactions | 1-naphthols | Ar reactions | Copper catalysis | Aryl halides | RING EXPANSION | CONVERSION | HYDROXYLATION | LIGNAN | CHEMISTRY, ORGANIC | BENZANNULATION | ETHERS | PHENOLS | ANNELATION | DERIVATIVES
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 2007, Volume 48, Issue 14, pp. 2563 - 2567
A novel complexity-generating reaction is described, which can be used in a high-throughput parallel solution-phase combinatorial format. The synthetic pathway... 
Ugi condensation | Parallel synthesis | Library | 3-Oxoisoindoline-1-carboxamides | library | FACILE SYNTHESIS | MCC/SNAR METHODOLOGY | CHEMISTRY, ORGANIC | 3-oxoisoindoline-1-carboxamides | ACCESS | parallel synthesis
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 06/2017, Volume 58, Issue 23, pp. 2306 - 2308
Two new synthetic routes were developed to prepare the RIP1 inhibitor clinical candidate GSK2982772 involving a key (S)-3-amino-benzo[b][1,4]oxazepin-4-one... 
RIP1 kinase inhibitor | SNAr cyclization | Mitsunobu | Benzo[b][1,4]oxazepin-4-one | Ar cyclization | NECROPTOSIS | INFLAMMATION | CHEMISTRY, ORGANIC
Journal Article
Tetrahedron, ISSN 0040-4020, 04/2014, Volume 70, Issue 17, pp. 2766 - 2775
Journal Article
Organic Letters, ISSN 1523-7060, 04/2019, Volume 21, Issue 7, pp. 2277 - 2280
An organocatalytic nucleophilic substitution reaction of gem-difluoroalkenes with ketene silyl acetals was developed. Phosphazene P4-tBu effectively catalyzed... 
FUNCTIONALIZATION | MONOFLUOROALKENYLATION | ACTIVATION | CHEMISTRY, ORGANIC | BOND MIMICS | STEREOSELECTIVE-SYNTHESIS | ARYL FLUORIDES | CATALYZED SNAR REACTION | CYCLIZATION | BORYLATION | FLUOROOLEFINS
Journal Article
Journal of Fluorine Chemistry, ISSN 0022-1139, 2002, Volume 115, Issue 1, pp. 91 - 99
Graphic Thermolysis of 2-[(polyfluorobenzylidene)amino]phenols in ethanol in the presence of triethylamine affords the corresponding fluorinated dibenz[ b,... 
Cyclisation | S NAr | Dibenzoxazepine | Crystal structure | crystal structure | CHEMISTRY, ORGANIC | cyclisation | SNAr | dibenzoxazepine | CHEMISTRY, INORGANIC & NUCLEAR
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 03/2018, Volume 59, Issue 11, pp. 1055 - 1058
[Display omitted] •Reaction of Reissert compound 1 via its anion with “stabilized” i-PrI yields four products.•The expected isopropyl compound 2 is isolated in... 
Isoindoloisoquinoline | SNAr | Isoquinoline Reissert compound | SRN1 | S(RN)1 | STEREOCHEMISTRY | CHEMISTRY, ORGANIC | NUCLEOPHILIC-SUBSTITUTION REACTIONS | ISOQUINOLINE | 1-ALKYL-2-ACYL-1,2-DIHYDROISOQUINALDONITRILES | CONSTRUCTION | DEACTIVATION RADICAL POLYMERIZATION | EFFICIENT | DERIVATIVES | CYCLIZATION | ALKALOIDS
Journal Article
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