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Journal of Leukocyte Biology, ISSN 0741-5400, 11/2014, Volume 96, Issue 5, pp. 895 - 905
Journal Article
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, ISSN 1684-1182, 06/2019
Interleukin 6 (IL-6) induce the inflammatory response directly related with the morbidity and mortality of neonatal. Here we aimed to explore the mechanism of... 
Journal Article
American Journal of Physiology - Gastrointestinal and Liver Physiology, ISSN 0193-1857, 2015, Volume 308, Issue 1, pp. G25 - G31
Journal Article
International Immunology, ISSN 0953-8178, 2009, Volume 21, Issue 6, pp. 679 - 689
Journal Article
NATURE IMMUNOLOGY, ISSN 1529-2908, 03/2015, Volume 16, Issue 3, pp. 286 - U252
Interleukin 17 (IL-17)-producing helper T cells (T(H)17 cells) and CD4(+) inducible regulatory T cells (iT(reg) cells) emerge from an overlapping developmental... 
FOXP3 EXPRESSION | SOCS3 | TGF-BETA | DENDRITIC CELLS | REGULATORY T-CELLS | HOST-DEFENSE | GENERATION | DIFFERENTIATION | IMMUNOLOGY | TH17 | PLASTICITY
Journal Article
Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, ISSN 1096-4959, 09/2019, p. 110348
Journal Article
Genes and Cancer, ISSN 1947-6019, 07/2011, Volume 2, Issue 7, pp. 720 - 727
Breast cancer is one of the most common cancers among women in the United States. Although there are effective drugs, such as cisplatin, for treating advanced... 
SOCS3 | breast cancer | microRNA 203 | Original
Journal Article
Journal of Sichuan University (Medical Science Edition), ISSN 1672-173X, 01/2018, Volume 49, Issue 1, pp. 1 - 7
Journal Article
Biomedicine & Pharmacotherapy, ISSN 0753-3322, 07/2019, Volume 115, p. 108913
Suppressor of cytokine signaling 3 (SOCS3) has been characterized as one of the most crucial negative regulator in the JAK2/STAT3 signaling pathway. However,... 
SOCS3/JAK2/STAT3 | Acute lymphoblastic leukemia | Methylation | Pediatric | Treg
Journal Article
Journal of immunology (Baltimore, Md. : 1950), ISSN 0022-1767, 5/2017, Volume 198, Issue 9, pp. 3536 - 3547
The aim of this study was to elucidate the expression and functions of interleukin (IL)-24 in C57BL/6 mouse corneas in response to Pseudomonas aeruginosa ( PA... 
bacterial keratitis | SOCS3 | interleukin 24 | innate immunity
Journal Article
International Journal of Oncology, ISSN 1019-6439, 05/2010, Volume 36, Issue 5, pp. 1201 - 1208
Journal Article
Environmental Pollution, ISSN 0269-7491, 10/2019, p. 113342
Journal Article
JOURNAL OF IMMUNOLOGY, ISSN 0022-1767, 04/2015, Volume 194, Issue 7, pp. 3422 - 3431
Increased TGF-beta 1 and TGF-beta 1-dependent Collagen I production in intestinal mesenchymal cells result in fibrosis in patients with Montreal B2... 
ENDOGENOUS IGF-I | FIBROSIS | CELLS | SOCS3 | INFLAMMATORY-BOWEL-DISEASE | GROWTH | GENE-EXPRESSION | INTESTINAL SMOOTH-MUSCLE | MICE | IMMUNOLOGY | TNBS-INDUCED COLITIS
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 02/2016, Volume 291, Issue 7, pp. 3508 - 3519
The suppressor of cytokine signaling (SOCS) proteins are negative regulators of the JAK/STAT pathway activated by proinflammatory cytokines, including the... 
PLASMA PCSK9 | tumor necrosis factor (TNF) | ACTIVATION | hepatocyte | proprotein convertase subtilisin | PROTEIN | insulin | CHOLESTEROL | BIOCHEMISTRY & MOLECULAR BIOLOGY | NECROSIS-FACTOR-ALPHA | APOLIPOPROTEIN-B | HUMAN ENDOTHELIAL-CELLS | INSULIN-RESISTANCE | stat-3 | HepG2 | kexin type 9 (PCSK9) | SMOOTH-MUSCLE-CELLS | MUTATIONS | suppressor of cytokine signaling 3 (SOCS3) | Proprotein Convertases - antagonists & inhibitors | Tumor Necrosis Factor-alpha - metabolism | Phosphorylation | Humans | STAT3 Transcription Factor - agonists | Tumor Necrosis Factor-alpha - genetics | Male | Janus Kinases - metabolism | Hepatocytes - metabolism | Proprotein Convertases - genetics | Recombinant Fusion Proteins - metabolism | RNA Interference | Serine Endopeptidases - genetics | Lipogenesis | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Recombinant Proteins - metabolism | Janus Kinases - chemistry | Signal Transduction | Mice, Inbred C57BL | Proprotein Convertases - metabolism | Insulin Resistance | Enzyme Induction | Suppressor of Cytokine Signaling Proteins - genetics | Serine Endopeptidases - chemistry | Proprotein Convertases - chemistry | Hep G2 Cells | Obesity - metabolism | Suppressor of Cytokine Signaling 3 Protein | Animals | Suppressor of Cytokine Signaling Proteins - antagonists & inhibitors | Suppressor of Cytokine Signaling Proteins - agonists | Obesity - enzymology | Protein Processing, Post-Translational | Serine Endopeptidases - metabolism | Mutation | Suppressor of Cytokine Signaling Proteins - metabolism | STAT3 Transcription Factor - antagonists & inhibitors | Hepatocytes - enzymology | Proprotein Convertase 9 | Cell Biology
Journal Article
Cytokine, ISSN 1043-4666, 11/2019, Volume 123, p. 154753
In the majority of myeloproliferative neoplasms (MPNs) patients, a point mutation, V617F has been found in Janus kinase 2 (JAK2) gene, and this JAK2 mutant... 
Myeloproliferative neoplasms (MPNs) | JAK2 V617F mutant | SOCS3 | Phosphorylation | SH2 domain
Journal Article
Frontiers in Neuroscience, ISSN 1662-453X, 06/2018, Volume 12
Currently, the etiology of Alzheimer’s disease (AD) is still elusive. Central insulin resistance has been determined to play an important role in the progress... 
SOCS3 | therapeutic target | Alzheimer’s disease | neuroinflammation | insulin resistance
Journal Article
European Review for Medical and Pharmacological Sciences, ISSN 1128-3602, 2019, Volume 23, Issue 5, pp. 2208 - 2215
OBJECTIVE: MicroRNAs are a group of gene expression regulators and some of which have been confirmed to be associated with acute viral myocarditis (VM). This... 
Coxsackievirus | SOCS3 | MicroRNA | Viral myocarditis | microRNA | PHARMACOLOGY & PHARMACY
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 2005, Volume 338, Issue 4, pp. 1943 - 1949
The precise role of IL-6 in liver regeneration and hepatocyte proliferation is controversial and the role of SOCS3 in liver regeneration remains unknown. Here... 
SOCS3 | HGF | IL-6 | Liver regeneration | p21
Journal Article
Hepatology (Baltimore, Md.), ISSN 0270-9139, 9/2012, Volume 56, Issue 3, pp. 1150 - 1159
Interleukin-22 (IL-22) is known to play a key role in promoting antimicrobial immunity, inflammation, and tissue repair at barrier surfaces by binding to the... 
SOCS3 | liver repair | IL-22R | p53
Journal Article
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