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Nature Reviews Neuroscience, ISSN 1471-003X, 01/2013, Volume 14, Issue 1, pp. 49 - 62
Journal Article
Journal of General Physiology, ISSN 0022-1295, 09/2018, Volume 150, Issue 9, pp. 1231 - 1232
Tandem studies investigate how propofol affects voltage-gated sodium channels. 
SODIUM-CHANNEL | PHYSIOLOGY | ISOFLURANE
Journal Article
NEURON, ISSN 0896-6273, 03/2019, Volume 101, Issue 5, pp. 765 - 767
Sodium channel Na(V)1.7 is a major target in pain research, largely because of genetic validation. In this issue of Neuron, McDermott et al. (2019) now present... 
NEUROSCIENCES
Journal Article
Brain, ISSN 0006-8950, 02/2019, Volume 142, Issue 2, pp. 263 - 275
Small fibre neuropathy leads to severe neuropathic pain. In a randomized, double-blind, crossover trial - the LENSS study - de Greef et al. evaluate the... 
Journal Article
Journal of Investigative Dermatology, ISSN 0022-202X, 05/2019, Volume 139, Issue 5, p. S114
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 02/2012, Volume 109, Issue 6, pp. E368 - E377
Journal Article
Cardiovascular Research, ISSN 0008-6363, 01/2012, Volume 93, Issue 1, pp. 12 - 23
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 08/2007, Volume 293, Issue 2, pp. 783 - 789
The blocking efficacy of 4,9-anhydro-TTX (4,9-ah-TTX) and TTX on several isoforms of voltage-dependent sodium channels, expressed in Xenopus laevis oocytes,... 
Tetrodotoxin | Sodium channel
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 2011, Volume 21, Issue 12, pp. 3676 - 3681
Starting from the oxindole identified through a high-throughput screening campaign, a series of Na 1.7 blockers were developed. Following the elimination of... 
Oxindole | Spirooxindole | Sodium channel | Pain | SCN9A
Journal Article
Circulation research, 02/2019, Volume 124, Issue 4, pp. 539 - 552
Mutations in the SCN5A gene, encoding the α subunit of the Nav1.5 channel, cause a life-threatening form of cardiac arrhythmia, long QT syndrome type 3 (LQT3).... 
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 05/2016, Volume 113, Issue 21, pp. 5856 - 5861
Journal Article
Bioorganic and Medicinal Chemistry Letters, ISSN 0960-894X, 08/2014, Volume 24, Issue 18, pp. 4397 - 4401
The voltage gated sodium channel Na v 1.7 represents an interesting target for the treatment of pain. Human genetic studies have identified the crucial role of... 
Na v 1.7 | Pain | Sodium channel | Benzenesulfonamide
Journal Article
American Journal of Physiology - Renal Physiology, ISSN 0363-6127, 07/2011, Volume 301, Issue 1, pp. F189 - F196
Journal Article
Brain Research, ISSN 0006-8993, 2004, Volume 1023, Issue 2, pp. 264 - 271
Inflammation caused by tissue damage results in pain, reflecting an increase in excitability of the primary afferent neurons innervating the area. There is... 
G-protein | Inflammation | Sodium channel
Journal Article
Behavioural Brain Research, ISSN 0166-4328, 03/2010, Volume 208, Issue 1, pp. 149 - 157
Two voltage gated sodium channels, Na 1.8 and Na 1.9, are exclusively expressed in primary sensory neurons and are suggested to play a role in different pain... 
Nociception | Knockout mice | Pain | Sodium channel
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 12/2006, Volume 26, Issue 50, pp. 12852 - 12860
We used a mouse with deletion of exons 4, 5, and 6 of the SCN11A (sodium channel, voltage-gated, type XI, α) gene that encodes the voltage-gated sodium channel... 
Sensory neuron | Nociceptor | Inflammation | Pain | Sodium channel | Peripheral sensitization | nociceptor | sensory neuron | pain | peripheral sensitization | sodium channel | inflammation
Journal Article
EMBO Journal, ISSN 0261-4189, 02/2018, Volume 37, Issue 3, pp. 427 - 445
The voltage-gated sodium channel Na 1.7 plays a critical role in pain pathways. We generated an epitope-tagged Na 1.7 mouse that showed normal pain behaviours... 
pain | sensory neuron | 1.7 | sodium channel | protein–protein interactor
Journal Article
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