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The Journal of biological chemistry, ISSN 0021-9258, 02/2015, Volume 290, Issue 8, pp. 4759 - 4771
Journal Article
Expert opinion on therapeutic targets, ISSN 1744-7631, 03/2009, Volume 13, Issue 4, pp. 485 - 496
... increase bone mass, lower adiposity and reduce fracture risk. Neutralizing antibodies to Dickkopf 1, secreted Frizzled-related protein 1 and sclerostin produce similar outcomes in animal models... 
Osteoporosis | Sfrp1 | Sclerostin | GSK-3 | SOST | Dkk1 | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Bone Morphogenetic Proteins - antagonists & inhibitors | Bone Morphogenetic Proteins - physiology | Humans | Glycogen Synthase Kinase 3 beta | Osteoporosis - drug therapy | LDL-Receptor Related Proteins - genetics | Intercellular Signaling Peptides and Proteins - physiology | beta Catenin - biosynthesis | Membrane Proteins - deficiency | Bone Diseases - drug therapy | Membrane Proteins - physiology | LDL-Receptor Related Proteins - deficiency | Intercellular Signaling Peptides and Proteins - deficiency | Drug Evaluation, Preclinical | Glycogen Synthase Kinase 3 - antagonists & inhibitors | Low Density Lipoprotein Receptor-Related Protein-5 | Membrane Proteins - genetics | Osteoblasts - drug effects | Osteoblasts - physiology | Osteogenesis - drug effects | Bone Resorption - drug therapy | Intercellular Signaling Peptides and Proteins - genetics | Bone Diseases - physiopathology | Organ Specificity | Regeneration - physiology | LDL-Receptor Related Proteins - physiology | beta Catenin - genetics | Mice, Knockout | Gene Expression Regulation - drug effects | Animals | Membrane Proteins - antagonists & inhibitors | Signal Transduction - drug effects | Protein Kinase Inhibitors - therapeutic use | Genetic Markers - physiology | Mice | Protein Kinase Inhibitors - pharmacology | Wnt Proteins - physiology | Wnt Proteins - antagonists & inhibitors | Fractures, Bone - drug therapy | Index Medicus
Journal Article
The New England journal of medicine, ISSN 1533-4406, 06/2016, Volume 374, Issue 26, pp. 2553 - 2562
Journal Article
PloS one, ISSN 1932-6203, 11/2015, Volume 10, Issue 11, pp. e0142058 - e0142058
Inhibitors of Wnt signaling have been shown to be involved in prostate cancer (PC) metastasis; however the role of Sclerostin (Sost) has not yet been explored.... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Wnt3A Protein - metabolism | Neoplasm Transplantation | Coculture Techniques | Humans | Bone Neoplasms - secondary | Male | Membrane Proteins - pharmacology | Bone Neoplasms - pathology | Intercellular Signaling Peptides and Proteins - metabolism | Bone Morphogenetic Proteins - metabolism | Heterografts | Prostatic Neoplasms - genetics | Neoplasm Invasiveness - pathology | Membrane Proteins - metabolism | Osteoblasts - cytology | Bone Morphogenetic Proteins - genetics | Bone Morphogenetic Proteins - pharmacology | Osteolysis - pathology | Prostatic Neoplasms - pathology | Membrane Proteins - genetics | Mice, Inbred C57BL | Intercellular Signaling Peptides and Proteins - genetics | Mice, Knockout | Animals | Wnt Signaling Pathway - genetics | Intercellular Signaling Peptides and Proteins - pharmacology | Genetic Markers - genetics | Cell Line, Tumor | Mice | Neoplasm Invasiveness - genetics | Osteoblasts - metabolism | Care and treatment | Patient outcomes | Development and progression | Genetic aspects | Research | Diagnosis | Prostate cancer | Tropism | Biotechnology | Wnt protein | Laboratories | Colorectal cancer | Cardiovascular disease | SOST protein | Biology | Metastasis | Osteolysis | Osteoblasts | Metastases | Cell adhesion & migration | Proteins | Liver cancer | Biomedical materials | Physical characteristics | Biocompatibility | Life sciences | Bone density | Elongation | Heparan sulfate | Invasiveness | Pseudopodia | Breast cancer | Gene expression | Signaling | Bone cancer | Ligands | In vivo methods and tests | Mutation | Dkk1 protein | Prostate | Cancer | Tumors | Index Medicus | 60 APPLIED LIFE SCIENCES
Journal Article
Biochemical and biophysical research communications, ISSN 0006-291X, 01/2012, Volume 417, Issue 2, pp. 830 - 835
Journal Article
Journal Article
The Lancet (British edition), ISSN 0140-6736, 2011, Volume 377, Issue 9773, pp. 1276 - 1287
Summary Osteoporosis is a common disease characterised by a systemic impairment of bone mass and microarchitecture that results in fragility fractures. With an... 
Internal Medicine | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Wnt Proteins - drug effects | Vitamin D Deficiency - complications | Calcium - metabolism | Bone Morphogenetic Proteins - immunology | Humans | Middle Aged | Osteoporosis - diagnosis | Osteoporosis, Postmenopausal - metabolism | Antibodies, Monoclonal - therapeutic use | Osteoporosis - drug therapy | Wnt Proteins - metabolism | Biphenyl Compounds - therapeutic use | Osteoporosis - etiology | Bone Remodeling - drug effects | Antibodies, Monoclonal, Humanized | Osteoporosis - metabolism | Vitamin D Deficiency - therapy | Aged, 80 and over | Bone Resorption - metabolism | Diphosphonates - therapeutic use | Female | Benzodioxoles - therapeutic use | RANK Ligand - therapeutic use | Anabolic Agents - therapeutic use | Osteoporosis - prevention & control | Risk Assessment | Osteoporotic Fractures - prevention & control | Risk Factors | Bone Resorption - drug therapy | Bone Density Conservation Agents - therapeutic use | Denosumab | Absorptiometry, Photon | Genetic Markers - immunology | Osteoclasts - metabolism | Osteoporosis, Postmenopausal - drug therapy | Randomized Controlled Trials as Topic | Bone Density - drug effects | Quinazolines - therapeutic use | Aged | Osteoblasts - metabolism | Intercellular Signaling Peptides and Proteins - immunology | Osteoporosis | Complications and side effects | Care and treatment | Diagnosis | Bones | Vitamin D | Womens health | Metabolic disorders | Index Medicus | Abridged Index Medicus | Cathepsin K | Cytokines | Proteinase | Socio-economic aspects | SOST protein | Osteoblasts | Post-menopause | Bone resorption | NF- Kappa B protein | Bone mass | Fractures | Reviews | Aging | Monoclonal antibodies | Osteoclasts | Dkk1 protein | Osteogenesis | Communication
Journal Article