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Cancer Letters, ISSN 0304-3835, 2014, Volume 358, Issue 2, pp. 210 - 219
Abstract Inconsistent results of SOX2 expression have been reported in gastric cancer (GC). Here, we demonstrated that SOX2 was progressively downregulated... 
Hematology, Oncology and Palliative Medicine | SOX2 | PTEN | Gastric cancer | Prognostic indicator | Tumor metastasis | BLADDER-CANCER | BOX PROTEIN SOX2 | DOWN-REGULATION | GROWTH-FACTOR-BETA | ONCOLOGY | COLORECTAL-CANCER | PROSTATE-CANCER | MICRORNA-B-10 PROMOTES MIGRATION | TUMOR-SUPPRESSOR | TRANSCRIPTION FACTOR SOX2 | HELICOBACTER-PYLORI | Stomach Neoplasms - genetics | Gene Expression | Cell Proliferation | Prognosis | Signal Transduction | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | PTEN Phosphohydrolase - metabolism | Stomach Neoplasms - metabolism | Apoptosis - genetics | Male | Stomach Neoplasms - pathology | Tumor Burden | SOXB1 Transcription Factors - metabolism | Neoplasm Metastasis | SOXB1 Transcription Factors - genetics | Adult | Female | Aged | Neoplasm Staging | Proto-Oncogene Proteins c-akt - metabolism | Stomach Neoplasms - mortality | Proteins | Metastasis | Stomach cancer | Analysis | Cancer | Cell proliferation | Transcription factors | AKT protein | Malignancy | Dephosphorylation | Multivariate analysis | Tissues | Metastases | Anticancer properties | DNA methylation | Sox2 protein | Deoxyribonucleic acid--DNA | Lymphatic system | Cell survival | Patients | Survival analysis | DNA microarrays | Medical prognosis | Laboratory animals | Binding sites | PTEN protein | Apoptosis | Tumors | Index Medicus
Journal Article
International Journal of Cancer, ISSN 0020-7136, 2019
The incidence of oropharyngeal squamous cell carcinoma (OPSCC) has been increasing due to high-risk HPV infection. We explored the significance of genetic... 
SOX2 | NOTCH1 | oropharynx | HPV | squamous cell carcinoma
Journal Article
The Journal of investigative dermatology, ISSN 0022-202X, 9/2018, Volume 138, Issue 9, pp. 1925 - 1934
Skin lipids (e.g. fatty acids) are essential for normal skin functions. Epidermal fatty acid-binding protein (E-FABP) is the predominant FABP expressed in skin... 
SOX2 | E-FABP | Keratinocyte | Skin tumorigenesis | p53
Journal Article
04/2013
In this paper, partial sequences of the tree shrew ( Tupaia belangeri ) Klf4, Sox2, and c-Myc genes were cloned and sequenced, which were 382, 612, and 485 bp... 
Sox2 | Tree shrew | c-Myc | Klf4 | Sequence analysis
Web Resource
Journal of Cell Science, ISSN 0021-9533, 2015, Volume 128, Issue 13, pp. 2303 - 2318
Journal Article
03/2012
Sox2 is the most frequently amplified oncogene in lung squamous cell carcinoma (SCC). Lung SCC arises in the proximal to central airways and is thought to... 
Sox2 | 0379 | lung progenitor | lung squamous cell carcinoma | basal cells
Dissertation
Oncotarget, ISSN 1949-2553, 03/2019, Volume 10, Issue 18, p. 1662
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 10/2019, Volume 861, p. 172599
The promoting roles of transcriptional factor six1 have been shown in various tumors, such as breast cancer and colorectal Cancer. However, its roles in... 
Six1 | Sox2 | Stemness | Hepatocellular carcinoma | 5-FU
Journal Article
Seminars in cancer biology, ISSN 1044-579X, 08/2019
The transcription factor SOX2 is essential for embryonic development and plays a crucial role in maintaining the stemness of embryonic cells and various adult... 
Journal Article
06/2010
The transcription factor Sox2 is one of the earliest determinants of the neural system in vertebrate and plays crucial roles in stem cell maintenance. Through... 
Sox2 | Xenopus laevis | Post-transcriptional regulation | 3'UTR
Web Resource
09/2007
We describe the temporal and spatial expression pattern of Sox1 gene during Xenopus laevis early development and compare the expression patterns of Sox1-3 in... 
Sox3 | Sox2 | Sox1 | Expression pattern | Xenopus laevis
Web Resource
by Wei, C.-X and Wong, H and Xu, F and Liu, Z and Ran, L and Jiang, R.-D
European Review for Medical and Pharmacological Sciences, ISSN 1128-3602, 2018, Volume 22, Issue 23, pp. 8169 - 8178
The aim of this study was to investigate the role of lncRNA SOX2-OT in the proliferation and metastasis of cholangiocarcinoma (CCA) and its underlying... 
SOX2 | Proliferation | Cholangiocarcinoma | PI3K/AKT signaling | SOX2-OT
Journal Article
Oncogene, ISSN 0950-9232, 05/2012, Volume 31, Issue 18, pp. 2270 - 2282
Tumors are thought to be sustained by a reservoir of self-renewing cells, termed tumor-initiating cells or cancer stem cells. Osteosarcomas are high-grade... 
mesenchymal tumors | wnt signaling | differentiation | cancer stem cell | osteosarcoma | sarcosphere | PROGENITOR CELLS | OSTEOBLAST DIFFERENTIATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | BETA-CATENIN | CANCER STEM-CELLS | CELL BIOLOGY | ONCOLOGY | MOUSE MODEL | GROWTH | SARCOMA | GENETICS & HEREDITY | TRANSCRIPTION FACTOR SOX2 | WNT | LINEAGE | Cell Proliferation | Signal Transduction | Membrane Proteins - genetics | Humans | Antigens, Ly - genetics | Antigens, Surface - genetics | Bone Neoplasms - pathology | Cell Differentiation - genetics | Animals | Neoplastic Stem Cells - metabolism | SOXB1 Transcription Factors - genetics | Cell Transformation, Neoplastic - genetics | Antigens, Surface - metabolism | Cell Line, Tumor | Neoplastic Stem Cells - pathology | Antigens, Ly - metabolism | Bone Neoplasms - genetics | Membrane Proteins - metabolism | Mice | Osteosarcoma - genetics | Osteosarcoma - pathology | Wnt Signaling Pathway | Transcription factors | Osteosarcoma | Stem cells | Physiological aspects | Genetic aspects | Research | Risk factors | Signal transduction | Oncology | Gene expression | Tumors | Osteoprogenitor cells | Pediatrics | Mesenchyme | Sarcoma | Wnt protein | biomarkers | Data processing | survival factor | Malignancy | Tumorigenicity | Self | Osteosarcoma cells | Osteoblasts | Mutation | Cancer | Sox2 | Wnt signaling | tumor initiating cell
Journal Article
GENOME MEDICINE, ISSN 1756-994X, 05/2013, Volume 5
Background: Human papillomavirus positive (HPV+) head and neck squamous cell carcinoma (HNSCC) is an emerging disease, representing a distinct clinical and... 
SOX2 | AMPLIFICATION | NOTCH1 | BIOLOGY | GENETICS & HEREDITY | HUMAN-PAPILLOMAVIRUS | MUTATIONS | ABERRATIONS | CANCER | LKB1 | MTOR
Journal Article
American Journal of Medical Genetics Part A, ISSN 1552-4825, 07/2019, Volume 179, Issue 7, pp. 1395 - 1397
Journal Article
Modern Pathology, ISSN 0893-3952, 07/2011, Volume 24, Issue 7, pp. 944 - 953
Journal Article
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