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Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2018, Volume 115, Issue 21, pp. 5474 - 5479
Mammalian sex determination is controlled by the antagonistic interactions of two genetic pathways: The SRY-SOX9-FGF9 network promotes testis determination... 
SOX9 Transcription Factor/genetics | Wnt Proteins/antagonists & inhibitors | Humans | Cells, Cultured | Testis/metabolism | Male | Zebrafish | Sex Differentiation | Mutation, Missense | Disorders of Sex Development/genetics | Young Adult | Animals | Gene Expression Regulation, Developmental | Adolescent | Gonads/metabolism | Embryo, Nonmammalian/cytology | Thrombospondins/genetics | Adult | Female | beta Catenin/antagonists & inhibitors | Mice | Ubiquitin-Protein Ligases/genetics | ZNRF3 | DSD | Sex determination | WNT signaling | Organogenesis | OVARIAN DEVELOPMENT | MULTIDISCIPLINARY SCIENCES | organogenesis | BETA-CATENIN | REVERSAL | R-SPONDIN | TUMOR-SUPPRESSOR | MICE | TESTIS DEVELOPMENT | SOX9 | DIFFERENTIATION | sex determination | CRITICAL TIME WINDOW | Embryo, Nonmammalian - cytology | Testis - metabolism | Thrombospondins - genetics | Embryo, Nonmammalian - metabolism | Gonads - pathology | Ubiquitin-Protein Ligases - physiology | Wnt Proteins - metabolism | Wnt Proteins - genetics | Disorders of Sex Development - pathology | SOX9 Transcription Factor - metabolism | Disorders of Sex Development - genetics | beta Catenin - metabolism | beta Catenin - genetics | Gonads - metabolism | Testis - pathology | beta Catenin - antagonists & inhibitors | Ubiquitin-Protein Ligases - genetics | Wnt Proteins - antagonists & inhibitors | SOX9 Transcription Factor - genetics | Thrombospondins - metabolism | Biological research | Physiological aspects | Genetic aspects | Cellular signal transduction | Research | Wnt proteins | Sex determination, Genetic | Biology, Experimental | Wnt Proteins / genetics | SOX9 Transcription Factor / metabolism | SOX9 Transcription Factor / genetics | beta Catenin / metabolism | Testis / pathology | Life Sciences | Gonads / metabolism | Thrombospondins / metabolism | Genetics | Testis / metabolism | beta Catenin / genetics | Disorders of Sex Development / pathology | beta Catenin / antagonists & inhibitors | Wnt Proteins / antagonists & inhibitors | Embryo, Nonmammalian / cytology | Wnt Proteins / metabolism | Ubiquitin-Protein Ligases / genetics | Gonads / pathology | Thrombospondins / genetics | Ubiquitin-Protein Ligases / physiology | Disorders of Sex Development / genetics | Embryo, Nonmammalian / metabolism | Human genetics | Biological Sciences
Journal Article
Development (Cambridge), ISSN 1477-9129, 2017, Volume 144, Issue 12, pp. 2294 - 2305
Journal Article
Developmental cell, ISSN 1534-5807, 2012, Volume 22, Issue 3, pp. 597 - 609
Journal Article
Journal Article
PLoS genetics, ISSN 1553-7390, 05/2013, Volume 9, Issue 5, p. e1003498
Journal Article
Oncogene, ISSN 1476-5594, 2019, Volume 38, Issue 17, pp. 3151 - 3169
Journal Article
Journal Article
Cancer cell, ISSN 1535-6108, 05/2012, Volume 21, Issue 5, pp. 601 - 613
The proto-oncogene MYCN is mis-expressed in various types of human brain tumors. To clarify how developmental and regional differences influence... 
PROGENITORS | SOX9 EXPRESSION | ONCOLOGY | SONIC HEDGEHOG | MOUSE MODEL | EMBRYONIC LETHALITY | PROLIFERATION | GENERATION | MUTATIONS | PEDIATRIC MEDULLOBLASTOMA | ASTROCYTES | CELL BIOLOGY | Oncogene Proteins - genetics | Cell Proliferation | Humans | Zinc Finger Protein Gli2 | Brain Stem - metabolism | Hedgehog Proteins - metabolism | Time Factors | Cell Transformation, Neoplastic - genetics | Glioma - pathology | Medulloblastoma - pathology | Cell Differentiation | N-Myc Proto-Oncogene Protein | Cerebellar Neoplasms - pathology | Prosencephalon - metabolism | Cerebellar Neoplasms - metabolism | Biomarkers - metabolism | Neuroectodermal Tumors, Primitive - metabolism | SOX9 Transcription Factor - metabolism | Transduction, Genetic | Signal Transduction | Oncogene Proteins - metabolism | Brain Neoplasms - genetics | Mice, Transgenic | Medulloblastoma - metabolism | Gestational Age | Cell Lineage | Mice, Nude | Brain Stem - embryology | Mice | Mutation | Brain Neoplasms - pathology | Brain Neoplasms - metabolism | Glioma - metabolism | Cerebellum - embryology | Hedgehog Proteins - genetics | Kruppel-Like Transcription Factors - metabolism | Female | Nuclear Proteins - genetics | Spheroids, Cellular | Proto-Oncogene Proteins - metabolism | Cerebellum - metabolism | Nuclear Proteins - metabolism | Proto-Oncogene Proteins - genetics | Cell Transformation, Neoplastic - metabolism | Neural Stem Cells - pathology | Animals | Cell Transformation, Neoplastic - pathology | Prosencephalon - embryology | Neural Stem Cells - metabolism | SOX9 Transcription Factor - genetics | Neuroectodermal Tumors, Primitive - pathology | Gliomas | Children's hospitals | Oncology, Experimental | Brain tumors | Stem cells | Transplantation | Universities and colleges | Research | Statistics | Tumors | Cancer | N-MYC | glioma | SOX9 | medulloblastoma | neural stem cells | GFAP
Journal Article
Development (Cambridge), ISSN 0950-1991, 06/2012, Volume 140, Issue 11, pp. 2280 - 2288
Journal Article