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1. Full Text IL-22+CD4+ T Cells Promote Colorectal Cancer Stemness via STAT3 Transcription Factor Activation and Induction of the Methyltransferase DOT1L
by Kryczek, Ilona and Lin, Yanwei and Nagarsheth, Nisha and Peng, Dongjun and Zhao, Lili and Zhao, Ende and Vatan, Linda and Szeliga, Wojciech and Dou, Yali and Owens, Scott and Zgodzinski, Witold and Majewski, Marek and Wallner, Grzegorz and Fang, Jingyuan and Huang, Emina and Zou, Weiping
Immunity (Cambridge, Mass.), ISSN 1074-7613, 05/2014, Volume 40, Issue 5, pp. 772 - 784
Life Sciences & Biomedicine | Immunology | Science & Technology | Receptors, CCR6 - immunology | Neoplasm Transplantation | Chemokine CCL20 - metabolism | Cell Proliferation | Homeodomain Proteins - metabolism | Humans | Methyltransferases - metabolism | Neoplastic Stem Cells - immunology | Homeodomain Proteins - immunology | Methyltransferases - immunology | Enzyme Activation - immunology | SOXB1 Transcription Factors - metabolism | CD4-Positive T-Lymphocytes - immunology | Chemokine CCL20 - immunology | SOXB1 Transcription Factors - immunology | Interleukins - immunology | Receptors, CCR6 - metabolism | Neoplastic Stem Cells - pathology | Octamer Transcription Factor-3 - immunology | STAT3 Transcription Factor - metabolism | Colorectal Neoplasms - mortality | Nanog Homeobox Protein | HT29 Cells | Animals | Colorectal Neoplasms - immunology | Octamer Transcription Factor-3 - metabolism | Cell Line, Tumor | Mice | STAT3 Transcription Factor - immunology | Colorectal Neoplasms - pathology | Medical research | Colon | Rodents | Colorectal cancer | Stem cells | Index Medicus | Th22 | colon cancer | DOT1L | STAT3 | ILC22 | Cancer stem cell | CCR6 | H3K79 | IL-22 | epigenetics
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2. Full Text Cooperative Binding of Transcription Factors Orchestrates Reprogramming
by Chronis, Constantinos and Fiziev, Petko and Papp, Bernadett and Butz, Stefan and Bonora, Giancarlo and Sabri, Shan and Ernst, Jason and Plath, Kathrin
Cell (Cambridge), ISSN 0092-8674, 01/2017, Volume 168, Issue 3, pp. 442 - 459.e20
reprogramming | Oct4 | Sox2 | collaborative binding | enhancers | transcription factors | induced pluripotent stem cells | pluripotency | Klf4 | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Chromatin - metabolism | Silencer Elements, Transcriptional | Proto-Oncogene Proteins c-fos - metabolism | Proto-Oncogene Proteins c-myc - metabolism | Cellular Reprogramming | SOXB1 Transcription Factors - metabolism | Transcription Factors - metabolism | Animals | Kruppel-Like Transcription Factors - metabolism | Regulatory Elements, Transcriptional | Octamer Transcription Factor-3 - metabolism | Histone Code | Mice | Fibroblasts - metabolism | Medical colleges | Chromatin | DNA binding proteins | Genomics | Stem cells | Stem cell research | Index Medicus
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3. Full Text Tissue damage and senescence provide critical signals for cellular reprogramming in vivo
by Mosteiro, Lluc and Pantoja, Cristina and Alcazar, Noelia and Marión, Rosa M and Chondronasiou, Dafni and Rovira, Miguel and Fernandez-Marcos, Pablo J and Muñoz-Martin, Maribel and Blanco-Aparicio, Carmen and Pastor, Joaquin and Gómez-López, Gonzalo and De Martino, Alba and Blasco, Maria A and Abad, María and Serrano, Manuel
Science (American Association for the Advancement of Science), ISSN 0036-8075, 11/2016, Volume 354, Issue 6315, pp. aaf4445 - aaf4445
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Genetic Loci | SOXB1 Transcription Factors - metabolism | Octamer Transcription Factor-3 - genetics | SOXB1 Transcription Factors - genetics | Kruppel-Like Transcription Factors - metabolism | Antineoplastic Agents - pharmacology | Induced Pluripotent Stem Cells - cytology | Cellular Reprogramming - genetics | Interleukin-6 - metabolism | Induced Pluripotent Stem Cells - metabolism | Cellular Senescence - genetics | Aniline Compounds - pharmacology | Mice, Inbred C57BL | Gene Expression Regulation | Cyclin-Dependent Kinase Inhibitor p16 - genetics | Transcription Factors - genetics | Sulfonamides - pharmacology | Proto-Oncogene Proteins c-myc - metabolism | Transcription Factors - metabolism | Teratoma - pathology | Animals | Octamer Transcription Factor-3 - metabolism | Cyclin-Dependent Kinase Inhibitor p16 - metabolism | Teratoma - genetics | Mice | Proto-Oncogene Proteins c-myc - genetics | Kruppel-Like Transcription Factors - genetics | Tissues | DNA damage | Cellular ceramic materials | Index Medicus | Cytokines | Interleukin | Mathematical models | In vivo methods and tests | In vitro testing | Damage | Recruitment
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4. Full Text Sequentially acting Sox transcription factors in neural lineage development
by Bergsland, Maria and Ramsköld, Daniel and Zaouter, Cécile and Klum, Susanne and Sandberg, Rickard and Muhr, Jonas
Genes & development, ISSN 0890-9369, 12/2011, Volume 25, Issue 23, pp. 2453 - 2464
Lineage formation | Neural stem cells | Sox genes | Neural development | Genetics & Heredity | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Cell Biology | Cell Line | Embryonic Stem Cells - metabolism | Up-Regulation | SOXC Transcription Factors - genetics | Embryonic Stem Cells - cytology | Neurons - cytology | Neurogenesis - genetics | Pluripotent Stem Cells - metabolism | Animals | SOXB1 Transcription Factors - genetics | Gene Expression Regulation, Developmental | SOX Transcription Factors - metabolism | SOX Transcription Factors - genetics | Mice | Neurons - metabolism | Genome | Cell Lineage - genetics | Genomes | Research | Embryonic stem cells | Genetic regulation | Health aspects | Neurogenesis | Index Medicus | Research Paper | neural development | lineage formation | neural stem cells | Medicin och hälsovetenskap
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5. Full Text Transient transcription factor (OSKM) expression is key towards clinical translation of in vivo cell reprogramming
by Lázaro, Irene and Cossu, Giulio and Kostarelos, Kostas
EMBO molecular medicine, ISSN 1757-4676, 06/2017, Volume 9, Issue 6, pp. 733 - 736
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Octamer Transcription Factor-3 - genetics | SOXB1 Transcription Factors - genetics | Humans | Gene Expression Regulation | Adult | Cell Differentiation | Transcription Factors | Cellular Reprogramming | Regeneration | Translation | KLF4 protein | Tissue engineering | Oct-4 protein | c-Myc protein | Tumorigenesis | Myc protein | Pluripotency | Index Medicus | Stem Cells | Commentaries | Regenerative Medicine
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6. Pituitary stalk interruption syndrome in 83 patients: Novel HESX1 mutation and severe hormonal prognosis in malformative forms
by Reynaud, R and Albarel, F and Saveanu, A and Kaffel, N and Castinetti, F and Lecomte, P and Brauner, R and Simonin, G and Gaudart, J and Carmona, E and Enjalbert, A and Barlier, A and Brue, T
European journal of endocrinology, ISSN 0804-4643, 04/2011, Volume 164, Issue 4, pp. 457 - 465
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Pituitary Gland - abnormalities | Pituitary Gland - pathology | Humans | Child, Preschool | Infant | Male | Transcription Factors - genetics | Homeodomain Proteins - genetics | Magnetic Resonance Imaging | SOXB1 Transcription Factors - genetics | Otx Transcription Factors - genetics | Adolescent | Female | LIM-Homeodomain Proteins | Mutation | Child
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7. Full Text Reprogramming of human somatic cells to pluripotency with defined factors
by Zhao, Rui and West, Jason A and Lerou, Paul H and Ince, Tan A and Huo, Hongguang and Lensch, M. William and Yabuuchi, Akiko and Daley, George Q and Park, In-Hyun
Nature (London), ISSN 0028-0836, 01/2008, Volume 451, Issue 7175, pp. 141 - 146
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Cell physiology | Molecular and cellular biology | Cell differentiation, maturation, development, hematopoiesis | Embryonic Stem Cells - metabolism | Embryonic Stem Cells - cytology | Humans | Transplantation, Heterologous | Gene Expression Profiling | Promoter Regions, Genetic - genetics | Octamer Transcription Factor-3 - genetics | DNA Methylation | Kruppel-Like Transcription Factors - metabolism | Cell Shape | HMGB Proteins - genetics | Adult | HMGB Proteins - metabolism | Cell Differentiation | SOXB1 Transcription Factors | Infant, Newborn | Nanog Homeobox Protein | Pluripotent Stem Cells - cytology | Cells, Cultured | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Proto-Oncogene Proteins c-myc - metabolism | Homeodomain Proteins - genetics | Fetus - cytology | Pluripotent Stem Cells - metabolism | Transcription Factors - metabolism | Teratoma - pathology | Animals | Octamer Transcription Factor-3 - metabolism | Pluripotent Stem Cells - transplantation | Fibroblasts - cytology | Mice | Proto-Oncogene Proteins c-myc - genetics | Kruppel-Like Transcription Factors - genetics | Physiological aspects | Genetic aspects | Research | DNA binding proteins | Gene expression | Somatic cells | Cell culture | Biomedical research | Cellular biology | Stem cells | Genetic engineering | Embryos | Index Medicus
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8. Full Text Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors
by Takahashi, Kazutoshi and Tanabe, Koji and Ohnuki, Mari and Narita, Megumi and Ichisaka, Tomoko and Tomoda, Kiichiro and Yamanaka, Shinya
Cell (Cambridge), ISSN 0092-8674, 2007, Volume 131, Issue 5, pp. 861 - 872
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Embryo, Mammalian | Fibroblasts - physiology | Humans | Male | Genes, myc | Cellular Reprogramming | DNA-Binding Proteins - metabolism | Octamer Transcription Factor-3 - genetics | Cell Differentiation - genetics | Kruppel-Like Transcription Factors - metabolism | HMGB Proteins - genetics | Neurons - physiology | Adult | Female | HMGB Proteins - metabolism | Telomerase - metabolism | SOXB1 Transcription Factors | Fibroblasts - metabolism | Biomarkers - metabolism | Transduction, Genetic | Pluripotent Stem Cells - physiology | Cells, Cultured | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Mice, Inbred ICR | Pluripotent Stem Cells - metabolism | Transcription Factors - metabolism | Teratoma - pathology | Animals | Myocytes, Cardiac - physiology | Octamer Transcription Factor-3 - metabolism | Aged | Mice | Kruppel-Like Transcription Factors - genetics | Stem cells | Index Medicus
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