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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2014, Volume 111, Issue 34, pp. 12426 - 12431
Pluripotency can be induced in somatic cells by overexpressing transcription factors, including POU class 5 homeobox 1 (OCT3/4), sex determining region Y-box 2... 
Phenotypes | Induced pluripotent stem cells | Somatic cells | Stem cells | Retroviridae | Embryonic stem cells | Pluripotent stem cells | Cellular differentiation | Cells | Mesenchymal stem cells | Epigenetics | Retrotransposon | Evolution | NONCODING RNA-ROR | ROADBLOCK | DNA METHYLATION | MULTIDISCIPLINARY SCIENCES | TRANSPOSABLE ELEMENTS | evolution | INDUCTION | epigenetics | IPS CELLS | PLURIPOTENT STEM-CELLS | PATHWAY | HUMAN FIBROBLASTS | retrotransposon | EXPRESSION | Octamer Transcription Factor-3 - physiology | Endogenous Retroviruses - physiology | Embryonic Stem Cells - cytology | Epigenesis, Genetic | Humans | Endogenous Retroviruses - genetics | Pluripotent Stem Cells - virology | Gene Knockdown Techniques | Octamer Transcription Factor-3 - genetics | Cell Differentiation - genetics | RNA, Viral - antagonists & inhibitors | RNA, Viral - genetics | SOXB1 Transcription Factors - genetics | Embryonic Stem Cells - virology | SOXB1 Transcription Factors - physiology | Induced Pluripotent Stem Cells - cytology | Cell Differentiation - physiology | Cellular Reprogramming - genetics | Gene Expression | Pluripotent Stem Cells - cytology | Induced Pluripotent Stem Cells - physiology | Induced Pluripotent Stem Cells - virology | Pluripotent Stem Cells - physiology | Kruppel-Like Transcription Factors - physiology | RNA, Long Noncoding - genetics | Embryonic Stem Cells - physiology | RNA, Long Noncoding - antagonists & inhibitors | Kruppel-Like Transcription Factors - genetics | Cellular Reprogramming - physiology | Epigenetic inheritance | Transcription factors | Retroviruses | Physiological aspects | Genetic research | Genetic aspects | Research | Cell differentiation | Gene expression | Virus research | Biological Sciences
Journal Article
Science, ISSN 0036-8075, 12/2007, Volume 318, Issue 5858, pp. 1917 - 1920
Journal Article
Stem Cells, ISSN 1066-5099, 11/2009, Volume 27, Issue 11, pp. 2667 - 2674
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 06/2011, Volume 121, Issue 6, pp. 2326 - 2335
Journal Article
Journal Article
Best Practice & Research: Clinical Endocrinology & Metabolism, ISSN 1521-690X, 2009, Volume 24, Issue 2, pp. 163 - 186
The process of sexual differentiation is central for reproduction of almost all metazoan, and therefore, for maintenance of practically all multicellular... 
Endocrinology & Metabolism | sex differentiation | ovary | disorders of sex development (DSD) | bipotential state | sex development | testis | sex determination | MULLERIAN DUCT SYNDROME | TUMOR SUPPRESSOR GENE | SUDDEN-INFANT-DEATH | PREMATURE OVARIAN FAILURE | STEROIDOGENIC FACTOR-I | WILMS-TUMOR | ENDOCRINOLOGY & METABOLISM | FOLLICLE-STIMULATING-HORMONE | MIXED GONADAL-DYSGENESIS | BONE MORPHOGENETIC PROTEIN-15 | TRANSCRIPTION FACTOR | Gonads - embryology | Sexual Development - genetics | Humans | Intramolecular Oxidoreductases - physiology | DAX-1 Orphan Nuclear Receptor - genetics | Male | Forkhead Transcription Factors - physiology | X-linked Nuclear Protein | Repressor Proteins - physiology | Anti-Mullerian Hormone - genetics | Hedgehog Proteins - genetics | SOXB1 Transcription Factors - genetics | Lipocalins - physiology | Female | SOXB1 Transcription Factors - physiology | Disorders of Sex Development - physiopathology | Nuclear Proteins - genetics | DNA Helicases - genetics | WT1 Proteins - genetics | Forkhead Box Protein L2 | DNA-Binding Proteins - physiology | Transcription Factors - physiology | DAX-1 Orphan Nuclear Receptor - physiology | Gonadal Dysgenesis - genetics | Sex Differentiation - genetics | Polycomb-Group Proteins | Transcription Factors - genetics | Disorders of Sex Development - genetics | Anti-Mullerian Hormone - physiology | Steroidogenic Factor 1 - physiology | Homeodomain Proteins - genetics | GATA4 Transcription Factor - physiology | WT1 Proteins - physiology | Sex Differentiation - physiology | Phenotype | Animals | PAX2 Transcription Factor - physiology | Sexual Development - physiology | LIM-Homeodomain Proteins | Nuclear Proteins - physiology | Wnt Proteins - physiology | Homeodomain Proteins - physiology | Wnt4 Protein | Bone morphogenetic proteins | Development and progression | Genetic disorders | Mental illness | Analysis
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2008, Volume 105, Issue 50, pp. 19756 - 19761
Embryonic stem cells have potential utility in regenerative medicine because of their pluripotent characteristics. Sall4, a zinc-finger transcription factor,... 
Transcription factors | Somatic cells | Genes | Stem cells | Cell lines | Antibodies | Promoter regions | Gene expression regulation | Embryonic stem cells | Pluripotent stem cells | Oct4 | Sox2 | Epigenetic regulation | Nanog | Induced pluripotent stem cells | DEVELOPMENTAL REGULATORS | MULTIDISCIPLINARY SCIENCES | COMPLEXES | SELF-RENEWAL | GENE SPALT | PROLIFERATION | epigenetic regulation | POLYCOMB | FIBROBLASTS | induced pluripotent stem cells | OKIHIRO-SYNDROME | MUTATIONS | EXPRESSION | Embryonic Stem Cells - metabolism | Epigenesis, Genetic | SOXB1 Transcription Factors - metabolism | DNA-Binding Proteins - metabolism | Octamer Transcription Factor-3 - genetics | DNA Methylation | Chromatin Immunoprecipitation | SOXB1 Transcription Factors - genetics | Gene Expression Regulation, Developmental | Kruppel-Like Transcription Factors - metabolism | Protein Structure, Tertiary | DNA-Binding Proteins - physiology | Transcription Factors - physiology | Pluripotent Stem Cells - physiology | Embryonic Development - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Proto-Oncogene Proteins c-myc - metabolism | Embryonic Stem Cells - physiology | Pluripotent Stem Cells - metabolism | Transcription Factors - metabolism | Animals | Octamer Transcription Factor-3 - metabolism | Mice | Proto-Oncogene Proteins c-myc - genetics | Genome | Kruppel-Like Transcription Factors - genetics | Epigenetic inheritance | Cellular control mechanisms | Genetic aspects | Genomes | Research | DNA binding proteins | Properties | Biological Sciences
Journal Article