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Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 1416 - 16
Pulmonary arterial hypertension (PAH) is a rare disorder with a poor prognosis. Deleterious variation within components of the transforming growth factor-beta... 
SOX17 | GENE | ANGIOGENESIS | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | BMP9 | ASSOCIATION | EXPRESSION | NONSENSE MUTATION | BETA-RECEPTOR | CAVEOLIN-1 | Prognosis | Humans | Male | Familial Primary Pulmonary Hypertension - diagnosis | SOXF Transcription Factors - metabolism | Aquaporin 1 - metabolism | Case-Control Studies | Familial Primary Pulmonary Hypertension - metabolism | Membrane Transport Proteins - genetics | Base Sequence | HEK293 Cells | Adult | Female | Growth Differentiation Factors - genetics | Membrane Transport Proteins - metabolism | Familial Primary Pulmonary Hypertension - pathology | Genetic Predisposition to Disease | Bone Morphogenetic Protein Receptors, Type II - genetics | Signal Transduction | Gene Expression Regulation | Adenosine Triphosphatases - metabolism | Models, Molecular | Familial Primary Pulmonary Hypertension - genetics | Bone Morphogenetic Protein Receptors, Type II - metabolism | Membrane Transport Proteins - chemistry | Whole Genome Sequencing | Aquaporin 1 - chemistry | Aquaporin 1 - genetics | Growth Differentiation Factors - metabolism | Transforming Growth Factor beta - genetics | Adenosine Triphosphatases - chemistry | Adenosine Triphosphatases - genetics | Mutation | SOXF Transcription Factors - genetics | Transforming Growth Factor beta - metabolism | SOXF Transcription Factors - chemistry | Growth Differentiation Factors - chemistry | Hypertension | Bone morphogenetic protein receptor type II | Secretion | Transforming growth factor | Genes | Genomes | Heritability | Aquaporin 1 | Gene sequencing
Journal Article
Journal Article
mAbs, ISSN 1942-0862, 05/2018, Volume 10, Issue 4, pp. 596 - 606
Antibodies are routinely used to study the activity of transcription factors, using various in vitro and in vivo approaches such as electrophoretic mobility... 
protein-protein interaction | antibody | SOX18 transcription factor | scFv | transcriptional activation | Single-Chain Antibodies | Humans | SOXF Transcription Factors - chemistry | SOXF Transcription Factors - analysis
Journal Article
Development, ISSN 0950-1991, 06/2006, Volume 133, Issue 11, pp. 2189 - 2200
In the zebrafish embryo, the mesoderm and endoderm originate from common precursors and segregate during gastrulation by mechanisms that are largely unknown.... 
Bon | BMP | FGF | Mesoderm | MAP kinase | Zebrafish | Casanova | Endoderm | ERK | bon | TRANSCRIPTION FACTORS | MOLECULAR NATURE | POSTERIOR DEVELOPMENT | ACTS DOWNSTREAM | endoderm | VERTEBRATE DEVELOPMENT | DEVELOPMENTAL BIOLOGY | mesoderm | TGF-BETA SIGNALS | NO TAIL | ONE-EYED-PINHEAD | zebrafish | HOMEOBOX PROTEIN | MESODERM INDUCTION | Phosphorylation | Transcription Factors - chemistry | Homeodomain Proteins - metabolism | Humans | Embryo, Nonmammalian - metabolism | Fibroblast Growth Factors - genetics | Molecular Sequence Data | Embryo, Nonmammalian - embryology | Extracellular Signal-Regulated MAP Kinases - metabolism | Zebrafish - embryology | DNA-Binding Proteins - metabolism | Fibroblast Growth Factors - metabolism | Bone Morphogenetic Proteins - metabolism | Gene Expression Regulation, Developmental | Conserved Sequence | SOXF Transcription Factors | Amino Acid Sequence | High Mobility Group Proteins - metabolism | Signal Transduction | Zebrafish Proteins - chemistry | Zebrafish Proteins - metabolism | High Mobility Group Proteins - chemistry | SOX Transcription Factors | Activin Receptors, Type I - metabolism | Transcription Factors - genetics | Mutation - genetics | DNA-Binding Proteins - chemistry | Homeodomain Proteins - genetics | Zebrafish - genetics | Endoderm - metabolism | Transcription Factors - metabolism | Phenotype | Sequence Alignment | Animals | Transforming Growth Factor beta - genetics | Zebrafish - metabolism | Zebrafish Proteins - genetics | Transforming Growth Factor beta - metabolism | Mitogen-Activated Protein Kinases - metabolism | Nodal Protein | Activin Receptors, Type I | High Mobility Group Proteins | Life Sciences | Fibroblast Growth Factors | Transforming Growth Factor beta | DNA-Binding Proteins | Mitogen-Activated Protein Kinases | Biochemistry, Molecular Biology | Zebrafish Proteins | Extracellular Signal-Regulated MAP Kinases | Homeodomain Proteins | Embryo, Nonmammalian | Transcription Factors | Mutation | Bone Morphogenetic Proteins | Molecular biology
Journal Article
Genome Medicine, ISSN 1756-994X, 07/2018, Volume 10, Issue 1, pp. 56 - 11
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 11/2001, Volume 29, Issue 21, pp. 4274 - 4283
The Sox gene family consists of several genes related by encoding a 79 amino acid DNA-binding domain known as the HMG box. This box shares strong sequence... 
SRY-RELATED GENE | MESSENGER-RNA | AUTOSOMAL SEX REVERSAL | CAMPOMELIC DYSPLASIA | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE | HYBRIDIZATION | MICE | MUTATIONS | BETA-CATENIN | PROTEINS | Chromosomes, Human, Pair 8 - genetics | Transcription Factors - chemistry | Cytoskeletal Proteins - antagonists & inhibitors | Humans | Transcriptional Activation | Synteny | Molecular Sequence Data | Gene Expression Profiling | Wnt Proteins | RNA, Messenger - metabolism | DNA-Binding Proteins - metabolism | Lymphoid Enhancer-Binding Factor 1 | Gene Expression Regulation, Developmental | Cloning, Molecular | Cytoskeletal Proteins - metabolism | SOXF Transcription Factors | Expressed Sequence Tags | Protein Structure, Tertiary | Amino Acid Sequence | Cell Line | Proto-Oncogene Proteins - antagonists & inhibitors | DNA-Binding Proteins - antagonists & inhibitors | High Mobility Group Proteins - metabolism | Signal Transduction | beta Catenin | Physical Chromosome Mapping | High Mobility Group Proteins - chemistry | RNA, Messenger - genetics | Trans-Activators | Zebrafish Proteins | Transcription Factors - antagonists & inhibitors | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Open Reading Frames - genetics | DNA-Binding Proteins - chemistry | Transcription Factors - metabolism | Sequence Alignment | Animals | Proto-Oncogene Proteins - physiology | Mice | High Mobility Group Proteins - genetics
Journal Article
Journal Article