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Science, ISSN 0036-8075, 07/2016, Volume 353, Issue 6298, pp. aaf1175 - aaf1175
The ability to write a stable record of identified molecular events into a specific genomic locus would enable the examination of long cellular histories and... 
MECHANISTIC BASIS | FOREIGN DNA | CAS ADAPTIVE IMMUNITY | TOGGLE SWITCH | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | ADAPTATION | GENETIC MEMORY | SYSTEMS | GENERATION | CELL FATE | Molecular biology | Genomics | Acquisitions | Deoxyribonucleic acid | Bacteria | Evolution | Recording | Devices | Spacers | Marketing
Journal Article
Nature Reviews Microbiology, ISSN 1740-1526, 01/2019, Volume 17, Issue 1, pp. 7 - 12
Many bacteria and archaea have the unique ability to heritably alter their genomes by incorporating small fragments of foreign DNA, called spacers, into CRISPR... 
SYSTEM | QUORUM SENSING CONTROLS | IMMUNITY | FOREIGN DNA | RNA | ADAPTATION | ACQUIRED-RESISTANCE | MICROBIOLOGY | HOST FACTOR | INTERFERENCE | HORIZONTAL GENE-TRANSFER | Molecular mechanics | RNA sequencing | Usage | Research | Gene expression | CRISPR | Immune response | Molecular modelling | Archaea | Spacer | Genomes | Nucleic acids | Immunity | Deoxyribonucleic acid--DNA | Spacers | Immune system
Journal Article
Cell, ISSN 0092-8674, 11/2018, Volume 175, Issue 4, pp. 934 - 946.e15
CRISPR-Cas systems confer an adaptive immunity against viruses. Following viral injection, Cas1-Cas2 integrates segments of the viral genome (spacers) into the... 
primed acquisition | CRISPR | DNA curtains | fluorescence microscopy | Cascade | ADAPTIVE IMMUNITY | SYSTEM | FOREIGN DNA | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | CASCADE | DEGRADATION | SURVEILLANCE COMPLEX | SPACER ACQUISITION | RNA-POLYMERASE | CELL BIOLOGY | DNA Curtains | Fluorescence Microscopy | Primed Acquisition
Journal Article
Nature, ISSN 0028-0836, 10/2018, Volume 562, Issue 7727, pp. 380 - 385
The ability to record transcriptional events within a cell over time would help to elucidate how molecular events give rise to complex cellular behaviours and... 
IMMUNITY | ELEMENTS | OXIDATIVE STRESS | READ ALIGNMENT | DNA | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | ADAPTATION | CAS SYSTEMS | GENOMIC FEATURES | REPEATS | RNA sequencing | Genetic aspects | Research | Genetic transcription | Escherichia coli | CRISPR | Oxidative stress | RNA viruses | Transcription | Genomics | Viruses | Genomes | Ribonucleic acid--RNA | Gene sequencing | E coli | Spacer | Recording | Bioinformatics | Deoxyribonucleic acid--DNA | Stimuli
Journal Article
Nature Protocols, ISSN 1754-2189, 03/2019, Volume 14, Issue 3, pp. 976 - 990
CRISPR-Cas systems are able to acquire immunological memories (spacers) from bacteriophages and plasmids in order to survive infection; however, this often... 
DIVERSITY | VIRUSES | ADAPTATION | BIOCHEMICAL RESEARCH METHODS | Bacteriophages | CRISPR | Integration | Ecosystems | Phages | Spacers | Harnesses | Polymerase chain reaction | Immunology | Plasmids | Spacer | Electrophoresis | Deoxyribonucleic acid--DNA | CRISPR array | adaptation | detection | spacer acquisition | CAPTURE | Microbiological Laboratory | Microbiologie | Microbiology | Laboratorium voor Microbiologie
Journal Article
Philosophical transactions of the Royal Society of London. Series B, Biological sciences, ISSN 0962-8436, 05/2019, Volume 374, Issue 1772, p. 20180092
We investigated the diversity of CRISPR spacers of Thermus communities from two locations in Italy, two in Chile and one location in Russia. Among the five... 
CRISPR | Thermus | diversity of spacers | Thermus phages | SYSTEM | RNA | CLASSIFICATION | HOST | EVOLUTIONARY DYNAMICS | STREPTOCOCCAL CRISPRS | PREDICTION | CAS | BIOLOGY | RESISTANCE | VIRUSES | 1001
Journal Article
RNA, ISSN 1355-8382, 10/2017, Volume 23, Issue 10, pp. 1525 - 1538
Journal Article
Microbial Ecology, ISSN 0095-3628, 7/2018, Volume 76, Issue 1, pp. 285 - 297
Journal Article