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06/2019
The invention provides compounds having the general formula I: and pharmaceutically acceptable salts thereof, wherein the variables R1, R2, R3, R4, subscipt m... 
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS | METALLURGY | HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | HETEROCYCLIC COMPOUNDS | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
07/2019
Compounds of formula (I) and salts are disclosed. Also disclosed are isotopes of compounds of formula I of the salts thereof. Pharmaceutical compositions... 
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS | METALLURGY | HYGIENE | ORGANIC CHEMISTRY | CHEMISTRY | HETEROCYCLIC COMPOUNDS | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
09/2019
Pharmaceutical compositions, kits and methods for treating tumors such as glioma and cancers such as leukemia with (R)-2-hydroxyglutarate (R-2HG) are provided,... 
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS | HYGIENE | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
09/2019
The invention relates to DNA vaccines that target multiple arenavirus agents singly or simultaneously. 
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS | HYGIENE | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
09/2019
This document provides methods and materials related to treating cancer. For example, methods and materials for using nucleic acid libraries to treat cancer... 
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS | HYGIENE | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
07/2019
L'invention concerne des compositions comprenant une ou plusieurs souches bactériennes pour traiter ou prévenir une hypersensibilité viscérale. 
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS | HYGIENE | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
08/2019
The invention provides a compound of formula I: wherein A 1 , A 2 , A 3 , R 1 , X , Y , and B have any of the values described herein, as well as salts of such... 
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS | METALLURGY | HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | HETEROCYCLIC COMPOUNDS | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
07/2019
Provided herein are, inter alia, methods, compositions, and kits for producing adipocyte populations such as beige adipocyte populations. Also included are... 
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS | HYGIENE | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
03/2019
and salts thereof, as well as pharmaceutical compositions comprising such compounds. The compounds are useful for treating cancers, Alzheimer's disease, and... 
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS | HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
06/2019
Provided herewith is a compound that reacts with a reactive lipid species to form a non- toxic product or an active product. Also provided is a method of... 
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS | HYGIENE | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
06/2019
Provided herein, inter alia, are compounds and methods for inhibiting PLK4 and for treating cancer in a subject in need thereof. La présente invention... 
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS | HYGIENE | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
02/2019
Compounds of formula (I) and salts are disclosed. Also disclosed are isotopes of compounds of formula I of the salts thereof. Pharmaceutical compositions... 
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS | METALLURGY | HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | HETEROCYCLIC COMPOUNDS | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
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