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PLoS ONE, ISSN 1932-6203, 01/2013, Volume 8, Issue 1, pp. e53708 - e53708
Background: Three-dimensional (3D) in-vitro cultures are recognized for recapitulating the physiological microenvironment and exhibiting high concordance with... 
THERAPY | 3RD-DIMENSION | SOLID TUMORS | SPHEROIDS | MULTIDISCIPLINARY SCIENCES | CANCER STEM-CELL | TISSUE | PENETRATION | EXTRACELLULAR-MATRIX | DRUG-RESISTANCE | SCAFFOLDS | Taxoids - pharmacology | Apoptosis - drug effects | Neoplastic Stem Cells - drug effects | Humans | Caspase 3 - metabolism | Spheroids, Cellular - pathology | Lung Neoplasms - pathology | Taxoids - metabolism | Cell Culture Techniques - methods | Antineoplastic Agents - metabolism | Nanoparticles | Biological Transport | Neoplastic Stem Cells - metabolism | Biomarkers, Tumor - metabolism | Inhibitory Concentration 50 | Neoplastic Stem Cells - pathology | Antineoplastic Agents - pharmacology | Spheroids, Cellular - drug effects | Gene Expression Regulation, Neoplastic - drug effects | Glucuronic Acid - chemistry | Drug Evaluation, Preclinical - methods | Spheroids, Cellular - metabolism | Docetaxel | Hexuronic Acids - chemistry | Alginates - chemistry | Cell Line, Tumor | Proto-Oncogene Proteins c-bcl-2 - genetics | Immunohistochemistry | Anthracyclines | Analysis | Tumors | Drugs | Cell culture | Camptothecin | Size distribution | 5-Fluorouracil | Toxicity | Lung cancer | Two dimensional models | Cytotoxicity | Mesothelioma | Drug resistance | Drug development | Drug screening | Caspase-3 | Doxorubicin | Anticancer properties | Angiogenesis | Biomedical materials | Antitumor agents | Biocompatibility | Pharmaceutical sciences | Formulations | Evaluation | Caspase | Cultures | Gene expression | Spheroids | Penetration resistance | Studies | Polymerase chain reaction | Pharmacy | Stem cells | Hypoxia | Three dimensional models | Scaffolds | Apoptosis | Cancer | Index Medicus
Journal Article
Journal of Cellular Biochemistry, ISSN 0730-2312, 09/2017, Volume 118, Issue 9, pp. 3003 - 3015
Journal Article
Journal of Cell Science, ISSN 0021-9533, 2017, Volume 130, Issue 1, pp. 203 - 218
Journal Article
Biotechnology and Bioengineering, ISSN 0006-3592, 10/2017, Volume 114, Issue 10, pp. 2360 - 2370
This study showcases a first instance of microfluidic 3D differentiation to generate functional hepatocyte‐like cells from a human liver progenitor cell... 
human stem cells | pump‐free | microfluidics | hepatocytes | 3D perfusion culture | pump-free | HEPARG CELLS | RAT HEPATOCYTES | TOXICITY | MODEL | CULTURE | PLURIPOTENT STEM-CELLS | METABOLISM | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | SHEAR-STRESS | LINE | BIOREACTOR | Organ Culture Techniques - methods | Tissue Engineering - methods | Cell Culture Techniques - instrumentation | Perfusion - instrumentation | Humans | Cell Proliferation - physiology | Cells, Cultured | Lab-On-A-Chip Devices | Stem Cells - cytology | Cell Culture Techniques - methods | Equipment Design | Tissue Engineering - instrumentation | Hepatocytes - cytology | Stem Cells - physiology | Organ Culture Techniques - instrumentation | Batch Cell Culture Techniques - instrumentation | Batch Cell Culture Techniques - methods | Cell Differentiation - physiology | Equipment Failure Analysis | Hepatocytes - physiology | Liver | Microfluidics | Stem cells | Cell culture | Animal models | Media (culture) | Rodents | Velocity measurement | Computer simulation | Maturation | Cultures | Flow rates | Spheroids | Hepatocytes | Simulation | Perfusion | Hydrostatic pressure | Computer applications | Cells (biology) | Media (differential) | Particle image velocimetry | Reservoirs | Pressure head | Differentiation | In vitro methods and tests | Viability | Index Medicus
Journal Article
Biomaterials, ISSN 0142-9612, 2015, Volume 80, pp. 106 - 120
Journal Article
Journal of Tissue Engineering and Regenerative Medicine, ISSN 1932-6254, 07/2017, Volume 11, Issue 7, pp. 2034 - 2045
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2014, Volume 9, Issue 9, pp. e108283 - e108283
3-dimensional (3D) culture models have the potential to bridge the gap between monolayer cell culture and in vivo studies. To benefit anti-cancer drug... 
BREAST-CANCER | TARGET | CELLS | IN-VITRO | MODELS | MULTIDISCIPLINARY SCIENCES | TISSUE | FIBROBLASTS | Human Umbilical Vein Endothelial Cells | Tubulin Modulators - pharmacology | Coculture Techniques | Epithelial Cells - drug effects | Humans | Receptor, ErbB-2 - metabolism | Male | Neoplasm Proteins - antagonists & inhibitors | Neoplasm Proteins - metabolism | Cell Culture Techniques - methods | Antineoplastic Agents - toxicity | Dose-Response Relationship, Drug | Protein Processing, Post-Translational - drug effects | Female | Antineoplastic Agents - pharmacology | Receptor, ErbB-2 - antagonists & inhibitors | Spheroids, Cellular - drug effects | Phosphorylation - drug effects | Antineoplastic Agents - classification | Tubulin Modulators - toxicity | Drug Screening Assays, Antitumor - methods | ErbB Receptors - antagonists & inhibitors | Cell Culture Techniques - instrumentation | Breast - cytology | Cells, Cultured | High-Throughput Screening Assays | Drug Screening Assays, Antitumor - instrumentation | Breast Neoplasms - pathology | Fibroblasts - drug effects | Cell Line, Tumor | Protein Kinase Inhibitors - toxicity | Protein Kinase Inhibitors - pharmacology | Miniaturization | Care and treatment | Diagnosis | Drug discovery | Cells | Cancer | Monomolecular films | Drugs | Cell culture | Toxicity | Epithelial cells | High-throughput screening | Cytotoxicity | Oncology | Kinases | Cancer therapies | Epidermal growth factor | Fibroblasts | Biocompatibility | Medical research | Sensitivity analysis | Epidermal growth factor receptors | Cultures | Breast cancer | FDA approval | Gene expression | Screens | Spheroids | Endothelial cells | Studies | Screening | Sensitivity | Inhibitors | Cell lines | Monolayers | In vivo methods and tests | Three dimensional models | Index Medicus
Journal Article
Journal Article