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Journal of atherosclerosis and thrombosis, ISSN 1880-3873, 2018, Volume 25, Issue 1, pp. 16 - 26
Journal Article
Arteriosclerosis, thrombosis, and vascular biology, ISSN 1524-4636, 2013, Volume 33, Issue 7, pp. 1505 - 1512
OBJECTIVE—Sphingosine 1-phosphate (S1P) partly accounts for antiatherogenic properties of high-density lipoproteins... 
Inflammation | High-density lipoproteins | T cells | Macrophage | Murine models of disease | Sphingosine 1-phosphate | CELLS | ACTIVATION | APOLIPOPROTEIN M | SPHINGOSINE-1-PHOSPHATE ANALOG | macrophage | high-density lipoproteins | DEFICIENT MICE | HYPERLIPIDEMIC MICE | murine models of disease | HIGH-DENSITY-LIPOPROTEIN | REDUCES ATHEROSCLEROSIS | inflammation | IMMUNE-RESPONSES | FTY720 | PERIPHERAL VASCULAR DISEASE | sphingosine 1-phosphate | HEMATOLOGY | Inflammation - pathology | Sulfhydryl Compounds - pharmacology | Atherosclerosis - genetics | Dendritic Cells - immunology | Humans | Aorta - metabolism | Aortic Diseases - metabolism | CD4-Positive T-Lymphocytes - immunology | Inflammation - metabolism | U937 Cells | Lipids - blood | Inflammation Mediators - metabolism | Receptors, LDL - deficiency | Aortic Diseases - prevention & control | Dendritic Cells - drug effects | Receptors, Lysosphingolipid - metabolism | Macrophages - immunology | Aortic Diseases - pathology | Disease Models, Animal | Receptors, LDL - genetics | Atherosclerosis - pathology | Atherosclerosis - immunology | Aortic Diseases - immunology | Aorta - drug effects | Aorta - immunology | Inflammation - immunology | Biomarkers - blood | Atherosclerosis - metabolism | Cardiovascular Agents - pharmacology | Mice, Knockout | Aorta - pathology | Endothelial Cells - immunology | Aortic Diseases - genetics | Animals | Signal Transduction - drug effects | Lymphocyte Activation - drug effects | CD8-Positive T-Lymphocytes - drug effects | Inflammation - genetics | Receptors, Lysosphingolipid - agonists | Macrophages - drug effects | Inflammation - prevention & control | Lymphopenia - immunology | Mice | CD8-Positive T-Lymphocytes - immunology | Macrophage Activation - drug effects | Atherosclerosis - prevention & control | CD4-Positive T-Lymphocytes - drug effects | Endothelial Cells - drug effects
Journal Article
Advances in biological regulation, ISSN 2212-4926, 05/2018, Volume 68, pp. 97 - 106
The bioactive lipid, sphingosine 1-phosphate (S1P) is produced by phosphorylation of sphingosine and this is catalysed by two sphingosine kinase isoforms (SK1 and SK2... 
Sphingosine kinase | Cancer cell-fibroblast interactions | Metastasis | Sphingosine 1-phosphate receptors | Sphingosine 1-phosphate | Phosphates | Enzymes | Protein-protein interactions | Sphingosine | Cancer
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2010, Volume 108, Issue 2, pp. 751 - 756
Journal Article
Trends in molecular medicine, ISSN 1471-4914, 2015, Volume 21, Issue 6, pp. 354 - 363
Highlights • S1P is a pleiotropic signaling molecule that regulates BBB permeability. • Fingolimod targets S1P receptors and may have therapeutic potential in... 
Pathology | blood–brain barrier | sphingosine 1-phosphate | neuroinflammation | astrocyte | fingolimod | multiple sclerosis | Neuroinflammation | Multiple sclerosis | Astrocyte | Blood-brain barrier | Fingolimod | Sphingosine 1-phosphate | blood-brain barrier | MEDICINE, RESEARCH & EXPERIMENTAL | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | RELAPSING MULTIPLE-SCLEROSIS | ORAL FINGOLIMOD | BIOCHEMISTRY & MOLECULAR BIOLOGY | ASTROCYTE-ENDOTHELIAL INTERACTIONS | PROTEIN-COUPLED RECEPTORS | FINGOLIMOD FTY720 | CELL BIOLOGY | VE-CADHERIN | CENTRAL-NERVOUS-SYSTEM | PLACEBO-CONTROLLED TRIAL | SPHINGOSINE-1-PHOSPHATE RECEPTOR 1 | Fingolimod Hydrochloride - pharmacology | Lysophospholipids - metabolism | Humans | Astrocytes - pathology | Capillary Permeability - drug effects | Lysophospholipids - immunology | Astrocytes - immunology | Sphingosine - metabolism | Receptors, Lysosphingolipid - metabolism | Astrocytes - drug effects | Blood-Brain Barrier - immunology | Endothelial Cells - metabolism | Sphingosine - immunology | Blood-Brain Barrier - drug effects | Blood-Brain Barrier - metabolism | Endothelial Cells - immunology | Blood-Brain Barrier - pathology | Receptors, Lysosphingolipid - immunology | Sphingosine - analogs & derivatives | Animals | Signal Transduction - drug effects | Multiple Sclerosis - immunology | Multiple Sclerosis - pathology | Endothelial Cells - pathology | Immunologic Factors - pharmacology | Astrocytes - metabolism | Endothelial Cells - drug effects | Multiple Sclerosis - drug therapy | Phosphates | Sphingosine | Permeability
Journal Article
Molecular Neurobiology, ISSN 0893-7648, 3/2018, Volume 55, Issue 3, pp. 2320 - 2332
Journal Article