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JOURNAL OF LIPID RESEARCH, ISSN 0022-2275, 03/2019, Volume 60, Issue 3, pp. 456 - 463
Sphingosine phosphate lyase (SPL) is the final enzyme in the sphingolipid degradative pathway, catalyzing the irreversible cleavage of long-chain base... 
HOMEOSTASIS | sphingosine phosphate lyase insufficiency syndrome | sphingolipids | ADRENAL INSUFFICIENCY | BIOCHEMISTRY & MOLECULAR BIOLOGY | SACCHAROMYCES-CEREVISIAE | DEFICIENCY | SGPL1 | SPHINGOSINE-1-PHOSPHATE LYASE | INHIBITION | METABOLISM | DEGRADATION | sphingosine-1-phosphate | NEPHROTIC SYNDROME | EXPRESSION
Journal Article
Journal Article
Journal Article
Immunological Reviews, ISSN 0105-2896, 05/2019, Volume 289, Issue 1, pp. 173 - 185
Journal Article
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 08/2011, Volume 45, Issue 2, pp. 426 - 435
A defining feature of acute lung injury (ALI) is the increased lung vascular permeability and alveolar flooding, which leads to associated morbidity and... 
Sphingosine-1-phosphate lyase | Acute lung injury | IL-6 | Intracellular sphingosine-1-phosphate | Transendothelial resistance | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE | PROTEIN-COUPLED RECEPTORS | BARRIER INTEGRITY | VEIN ENDOTHELIAL-CELLS | intracellular sphingosine-1-phosphate | acute lung injury | SPHINGOSINE 1-PHOSPHATE | FAMILY | CELL BIOLOGY | PHOSPHATE | transendothelial resistance | PLASMA | sphingosine-1-phosphate lyase | RESPIRATORY SYSTEM | ENHANCEMENT | EXPRESSION | Endothelium, Vascular - cytology | Lysophospholipids - metabolism | RNA, Small Interfering - genetics | Humans | Pneumonia - prevention & control | Bronchoalveolar Lavage | Endothelium, Vascular - drug effects | Immunoblotting | NF-kappa B - metabolism | Acute Lung Injury - enzymology | Tandem Mass Spectrometry | Acute Lung Injury - prevention & control | Pneumonia - chemically induced | Sphingosine - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | Phosphorylation - drug effects | Interleukin-6 - metabolism | Lipopolysaccharides - toxicity | Pneumonia - enzymology | Mice, Inbred C57BL | Cells, Cultured | Injections, Intraperitoneal | Aldehyde-Lyases - antagonists & inhibitors | Aldehyde-Lyases - physiology | Mice, Knockout | Sphingosine - analogs & derivatives | Animals | Acute Lung Injury - chemically induced | NF-kappa B - genetics | Endothelium, Vascular - metabolism | Mice
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2016, Volume 113, Issue 7, pp. 1901 - 1906
Journal Article
Journal Article
Journal Article
Science, ISSN 0036-8075, 9/2005, Volume 309, Issue 5741, pp. 1735 - 1739
Lymphocyte egress from the thymus and from peripheral lymphoid organs depends on sphingosine 1-phosphate (S1P) receptor-1 and is thought to occur in response... 
Spleen | T lymphocytes | Thymocytes | Lymphocytes | B lymphocytes | Reports | Lymphoid tissue | Blood | Lymph nodes | Lymph | Blood plasma | EMIGRATION | MIGRATION | THYMUS | PYRIDOXINE | AMMONIA PROCESS | METABOLISM | MULTIDISCIPLINARY SCIENCES | SPHINGOSINE-1-PHOSPHATE | RECEPTOR | T-CELLS | SPHINGOSINE 1-PHOSPHATE | Chemotaxis, Leukocyte | Lysophospholipids - metabolism | T-Lymphocytes - physiology | Vitamin B 6 - pharmacology | Lymph - immunology | Pyridoxine - analogs & derivatives | Lymphoid Tissue - immunology | RNA Interference | Lymph - metabolism | Hematopoietic Stem Cells - physiology | Sphingosine - metabolism | Aldehyde-Lyases - genetics | Receptors, Lysosphingolipid - metabolism | Thymus Gland - metabolism | Immunosuppressive Agents - pharmacology | Pyridoxine - pharmacology | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | B-Lymphocytes - physiology | Lymphoid Tissue - metabolism | Food Coloring Agents - pharmacology | Aldehyde-Lyases - antagonists & inhibitors | Imidazoles - pharmacology | Lysophospholipids - blood | Lymph Nodes - immunology | Sphingosine - analogs & derivatives | Animals | B-Lymphocytes - immunology | Aldehyde-Lyases - metabolism | Sphingosine - blood | T-Lymphocytes - immunology | Thymus Gland - immunology | Mice | Lymphopenia - chemically induced | Lyases | Research | Observations | Lymphocyte receptors | Enzymes | Lymphatic system | Rodents
Journal Article
Human Mutation, ISSN 1059-7794, 04/2017, Volume 38, Issue 4, pp. 365 - 372
Journal Article