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The Journal of Cell Biology, ISSN 0021-9525, 2/2009, Volume 184, Issue 3, pp. 383 - 390
Journal Article
Nature Cell Biology, ISSN 1465-7392, 11/2013, Volume 15, Issue 11, pp. 1370 - 1377
The mitotic spindle assembly checkpoint (SAC) delays anaphase onset until all chromosomes have attached to both spindle poles(1,2). Here, we investigated SAC... 
CDC20 | ANEUPLOIDY | ANAPHASE | SATISFY | ROLES | DRIVES | CDK1 | MITOTIC CHECKPOINT | CHROMOSOMAL INSTABILITY | REVEALS | CELL BIOLOGY | M Phase Cell Cycle Checkpoints | Chromosomes, Human | Signal Transduction | Humans | Kinetochores | Spindle Apparatus | Spindle (Cell division) | Cell division | Aneuploidy | Genetic aspects | Cellular signal transduction | Properties | Testing | Index Medicus
Journal Article
Journal Article
Nature Cell Biology, ISSN 1465-7392, 11/2013, Volume 15, Issue 11, pp. 1378 - 1385
Journal Article
Nature, ISSN 0028-0836, 08/2016, Volume 536, Issue 7617, pp. 431 - 436
In the dividing eukaryotic cell, the spindle assembly checkpoint (SAC) ensures that each daughter cell inherits an identical set of chromosomes. The SAC... 
MAD2 | ANAPHASE-PROMOTING COMPLEX | MECHANISM | CDC20 BINDING | UCSF CHIMERA | PHOSPHORYLATION | PROTEIN BUBR1 | MULTIDISCIPLINARY SCIENCES | RECOMBINANT EXPRESSION | MITOTIC CHECKPOINT | SACCHAROMYCES-CEREVISIAE | Spindle Apparatus - chemistry | Humans | Protein-Serine-Threonine Kinases - ultrastructure | Structure-Activity Relationship | Anaphase-Promoting Complex-Cyclosome - antagonists & inhibitors | Anaphase-Promoting Complex-Cyclosome - ultrastructure | Protein Subunits - metabolism | Ubiquitin-Conjugating Enzymes - chemistry | Ubiquitination | Spindle Apparatus - metabolism | Cdc20 Proteins - chemistry | Anaphase-Promoting Complex-Cyclosome - chemistry | Spindle Apparatus - ultrastructure | Protein-Serine-Threonine Kinases - metabolism | Cdc20 Proteins - ultrastructure | Chromosome Segregation | Biocatalysis | Kinetochores - metabolism | Cell Cycle Proteins - metabolism | Ubiquitin-Protein Ligases - metabolism | Models, Molecular | Ubiquitin-Conjugating Enzymes - ultrastructure | Cryoelectron Microscopy | Ubiquitin-Conjugating Enzymes - metabolism | Cdc20 Proteins - metabolism | Protein Binding | Protein Conformation | Protein Subunits - chemistry | Protein-Serine-Threonine Kinases - chemistry | Anaphase-Promoting Complex-Cyclosome - metabolism | M Phase Cell Cycle Checkpoints - physiology | Spindle (Cell division) | Physiological aspects | Research | Molecular biology | Ligases | Cell division | Kinases | Chromosomes | Binding sites | Crystal structure | Index Medicus
Journal Article
The EMBO Journal, ISSN 0261-4189, 04/2009, Volume 28, Issue 8, pp. 1099 - 1110
The protein kinase Mps1 is, among others, essential for the spindle assembly checkpoint (SAC). We found that Saccharomyces cerevisiae Mps1 interacts physically... 
kinetochore | centromere | Mps1 | spindle assembly checkpoint | Ndc80 | Kinetochore | Centromere | Spindle assembly checkpoint | BI-ORIENTATION | COMPLEX | BUDDING YEAST | PROTEIN-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | POLE BODY DUPLICATION | TENSION | CELL BIOLOGY | MPS1 KINASE | GENE MPS1 | MITOTIC CHECKPOINT | KINETOCHORE-MICROTUBULE ATTACHMENT | Protein Kinases - metabolism | Phosphorylation | Protein Kinases - genetics | Protein-Tyrosine Kinases - metabolism | Saccharomyces cerevisiae - genetics | Molecular Sequence Data | Recombinant Fusion Proteins - metabolism | Saccharomyces cerevisiae - metabolism | Microtubules - metabolism | Protein-Tyrosine Kinases - genetics | Spindle Apparatus - metabolism | Nuclear Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Amino Acid Sequence | Kinetochores - metabolism | Protein-Serine-Threonine Kinases - genetics | Intracellular Signaling Peptides and Proteins | Alanine - metabolism | Nuclear Proteins - metabolism | Aurora Kinases | Saccharomyces cerevisiae Proteins - genetics | Animals | Saccharomyces cerevisiae Proteins - metabolism | Cell Cycle - physiology | Recombinant Fusion Proteins - genetics | Aspartic Acid - metabolism | Signal Transduction - physiology | Genes, cdc | Signal transduction | Biochemistry | Kinases | Molecular biology | Cell cycle | Index Medicus
Journal Article
Nature Cell Biology, ISSN 1465-7392, 07/2015, Volume 17, Issue 7, pp. 868 - 879
The spindle assembly checkpoint (SAC) is a unique signalling mechanism that responds to the state of attachment of the kinetochore to spindle microtubules. SAC... 
NDC80 COMPLEX | RECRUITMENT | BUDDING YEAST | MPS1 | PHOSPHORYLATION | CHROMOSOME CONGRESSION | KINASE | MICROTUBULE ATTACHMENT | MITOTIC SPINDLE | PROTEIN ARCHITECTURE | CELL BIOLOGY | Phosphorylation | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Saccharomyces cerevisiae - genetics | Tubulin Modulators - pharmacology | Nocodazole - pharmacology | Saccharomyces cerevisiae - drug effects | Saccharomyces cerevisiae - metabolism | Microtubules - metabolism | Spindle Apparatus - metabolism | Cell Cycle Proteins - genetics | Cell Cycle Checkpoints - genetics | Time-Lapse Imaging - methods | Nuclear Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Aurora Kinases - metabolism | Kinetochores - metabolism | Aurora Kinases - genetics | Cell Cycle Proteins - metabolism | Protein-Serine-Threonine Kinases - genetics | Cell Cycle Checkpoints - physiology | Nuclear Proteins - metabolism | Signal Transduction - genetics | Saccharomyces cerevisiae Proteins - genetics | Sirolimus - pharmacology | Signal Transduction - drug effects | Cell Cycle Checkpoints - drug effects | Saccharomyces cerevisiae Proteins - metabolism | Protein Binding | Luminescent Proteins - genetics | Signal Transduction - physiology | Microscopy, Fluorescence | Luminescent Proteins - metabolism | Spindle (Cell division) | Cellular signal transduction | Genetic aspects | Properties | Kinetochores | Index Medicus
Journal Article
Cell Cycle, ISSN 1538-4101, 07/2016, Volume 15, Issue 13, pp. 1661 - 1662
Journal Article