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世界胃肠病学杂志:英文版(电子版), ISSN 1007-9327, 2014, Volume 20, Issue 44, pp. 16674 - 16682
AIM: To investigate the effects of Glytan on splanchnic hemodynamics and its reduction of portal pressure in portal hypertensive rats.METHODS:Glytan(Ganluotong... 
Portal | Hemodynam-ics | Mesentery | hypertension | Glytan | Sensitivity | Receptor | Endothelin-1 | Portal hypertension | Hemodynamics | ETB RECEPTORS | ENDOTHELIAL DYSFUNCTION | ANGIOGENESIS | PHOSPHORYLATION | NITRIC-OXIDE SYNTHASE | DESENSITIZATION | COUPLED RECEPTOR KINASES | HYPERDYNAMIC CIRCULATION | CIRRHOSIS | VASODILATION | GASTROENTEROLOGY & HEPATOLOGY | Hypertension, Portal - physiopathology | Drugs, Chinese Herbal - pharmacology | Benzofurans - pharmacology | Male | Endothelin B Receptor Antagonists - pharmacology | G-Protein-Coupled Receptor Kinase 2 - metabolism | Hypertension, Portal - enzymology | G-Protein-Coupled Receptor Kinase 2 - antagonists & inhibitors | Portal Pressure - drug effects | Glycyrrhetinic Acid - pharmacology | Time Factors | Mesentery - drug effects | Nitric Oxide Synthase Type III - metabolism | Disease Models, Animal | Vasoconstrictor Agents - pharmacology | Receptor, Endothelin B - drug effects | Splanchnic Circulation - drug effects | Glycyrrhetinic Acid - analogs & derivatives | Mesentery - enzymology | Rats, Sprague-Dawley | Vasoconstriction - drug effects | Hypertension, Portal - drug therapy | Endothelin-1 - blood | Mesentery - blood supply | Nitric Oxide Synthase Type III - antagonists & inhibitors | Animals | Signal Transduction - drug effects | Blood Flow Velocity | Hypertension, Portal - blood | Protein Kinase Inhibitors - pharmacology | Receptor, Endothelin B - metabolism | Original
Journal Article
Journal Article
Journal of Pharmacological Sciences, ISSN 1347-8613, 2009, Volume 111, Issue 4, pp. 372 - 380
We previously reported that endothelium-derived hyperpolarizing factor (EDHF)– mediated response time-dependently suppressed methoxamine-induced... 
endothelium-derived contracting factor | aging | methoxamine-induced vasoconstriction | endothelium-derived hyperpolarizing factor | rat mesenteric resistance artery | Methoxamine-induced vasoconstriction | Aging | Endothelium-derived contracting factor | Endothelium-derived hyperpolarizing factor | Rat mesenteric resistance artery | NERVES | RESISTANCE ARTERIES | AORTA | RESPONSES | HYPERPOLARIZING FACTOR | BLOOD-VESSELS | PHARMACOLOGY & PHARMACY | DEPENDENT RELAXATIONS | DYSFUNCTION | HYPERTENSION | Catalase - pharmacology | Rats, Wistar | Endothelium, Vascular - drug effects | Male | Spin Labels | Splanchnic Circulation - radiation effects | Methoxamine - antagonists & inhibitors | Endothelium, Vascular - physiology | Drug Interactions | Cyclic N-Oxides - pharmacology | Potassium Chloride - pharmacology | Biological Factors - metabolism | Heptanoic Acids - pharmacology | NG-Nitroarginine Methyl Ester - pharmacology | Vasoconstrictor Agents - pharmacology | Splanchnic Circulation - drug effects | Vasodilator Agents - pharmacology | Vasoconstrictor Agents - antagonists & inhibitors | Acetylcholine - pharmacology | Rats | Calcimycin - pharmacology | Vasoconstriction - drug effects | Indomethacin - pharmacology | Benzoquinones - pharmacology | Animals | Deoxycholic Acid - pharmacology | Endothelium, Vascular - metabolism | Methoxamine - pharmacology
Journal Article
Journal Article
HEPATOLOGY, ISSN 0270-9139, 04/2001, Volume 33, Issue 4, pp. 816 - 820
Portal hypertension is associated with increased hepatic and collateral resistance to an increased portal blood flow. Endothelin-1 (ET-1) can induce... 
ETB RECEPTORS | PRESSURE | VASCULAR TONE | SPLANCHNIC HEMODYNAMICS | PROSTACYCLIN | LIVER | NITRIC-OXIDE | GASTROENTEROLOGY & HEPATOLOGY | EXPRESSION | RECEPTOR ANTAGONIST | ET(B) RECEPTOR
Journal Article
Journal Article