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1. Full Text Hypertensive renal disease: Susceptibility and resistance in inbred hypertensive rat lines
by Braun, Michael C and Herring, Stacy M and Gokul, Nisha and Monita, Monique and Bell, Rebecca and Hicks, M. John and Wenderfer, Scott E and Doris, Peter A
Journal of hypertension, ISSN 0263-6352, 10/2013, Volume 31, Issue 10, pp. 2050 - 2059
Hypertension | Renal injury | Rat model | Genetics | Mapping | Spontaneously hypertensive rat | Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Albuminuria - pathology | Blood Pressure | Haplotypes | Kidney Diseases - physiopathology | Rats, Inbred SHR | Genetic Predisposition to Disease | Kidney - pathology | Rats | Genotype | Male | Chromosome Mapping | Kidney Glomerulus - pathology | Hypertension - physiopathology | Kidney Diseases - genetics | Hypertension - metabolism | Animals | Polymorphism, Single Nucleotide | Fibrosis - pathology | Hypertension - genetics | Kidney Tubules - pathology | Quantitative Trait Loci | Crosses, Genetic | Kidney Diseases - metabolism | Index Medicus
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2. Full Text Antihypertensive Effect of a γ-Aminobutyric Acid Rich Tomato Cultivar ‘DG03-9’ in Spontaneously Hypertensive Rats
by Yoshimura, Mineka and Toyoshi, Tohru and Sano, Atsushi and Izumi, Toru and Fujii, Takashi and Konishi, Chiaki and Inai, Shuji and Matsukura, Chiaki and Fukuda, Naoya and Ezura, Hiroshi and Obata, Akio
Journal of agricultural and food chemistry, ISSN 0021-8561, 01/2010, Volume 58, Issue 1, pp. 615 - 619
Food Chemistry/Biochemistry | Hypertension | Spontaneously hypertensive rats | Tomato | γ-aminobutyric acid | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Applied | Food Science & Technology | Agriculture, Multidisciplinary | Agriculture | Science & Technology | Fundamental and applied biological sciences. Psychology | Food industries | Biological and medical sciences | Fruit and vegetable industries | Rats, Inbred SHR | Humans | Antihypertensive Agents - administration & dosage | Rats | Hypertension - drug therapy | Male | gamma-Aminobutyric Acid - administration & dosage | Hypertension - physiopathology | Plant Extracts - administration & dosage | Animals | Blood Pressure - drug effects | Lycopersicon esculentum - chemistry | Disease Models, Animal | Index Medicus
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3. Full Text Preventive and treatment effects of a hemp seed (Cannabis sativa L.) meal protein hydrolysate against high blood pressure in spontaneously hypertensive rats
by Girgih, Abraham T and Girgih, Abraham T and Alashi, Adeola and Alashi, Adeola and He, Rong and He, Rong and Malomo, Sunday and Malomo, Sunday and Aluko, Rotimi E and Aluko, Rotimi E
European journal of nutrition, ISSN 1436-6207, 8/2014, Volume 53, Issue 5, pp. 1237 - 1246
Systolic blood pressure | Chemistry | Protein hydrolysate | Nutrition | Hemp seed meal | Plasma ACE activity | Spontaneously hypertensive rats | Plasma renin activity | Life Sciences & Biomedicine | Nutrition & Dietetics | Science & Technology | Fundamental and applied biological sciences. Psychology | Feeding. Feeding behavior | Cardiology. Vascular system | Arterial hypertension. Arterial hypotension | Vertebrates: anatomy and physiology, studies on body, several organs or systems | Biological and medical sciences | Medical sciences | Blood and lymphatic vessels | Experimental diseases | Rats, Inbred SHR | Antihypertensive Agents - pharmacology | Amino Acids - analysis | Rats | Rats, Inbred WKY | Hypertension - drug therapy | Male | Renin - blood | Protein Hydrolysates - pharmacology | Cannabis - chemistry | Animals | Peptidyl-Dipeptidase A - blood | Plant Preparations - pharmacology | Blood Pressure - drug effects | Seeds - chemistry | Hypertension | Prevention | Enzymes | Casein | Functional foods | Protein hydrolysates | Angiotensin | Marijuana | Blood pressure | Index Medicus
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4. Full Text Angiotensin-(1-7) modulates renin–angiotensin system associated with reducing oxidative stress and attenuating neuronal apoptosis in the brain of hypertensive rats
by Jiang, Teng and Gao, Li and Shi, Jianquan and Lu, Jie and Wang, Yao and Zhang, Yingdong
Pharmacological research, ISSN 1043-6618, 01/2013, Volume 67, Issue 1, pp. 84 - 93
Renin–angiotensin system | Brain | Oxidative stress | Neuronal apoptosis | Spontaneously hypertensive rat | Angiotensin-(1-7) | Renin-angiotensin system | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Antihypertensive Agents - pharmacology | Apoptosis - drug effects | Rats, Inbred WKY | Angiotensin I - therapeutic use | Hypertension - drug therapy | Male | Peptide Fragments - pharmacology | Angiotensin I - pharmacology | Blood Pressure - drug effects | Neurons - drug effects | Superoxide Dismutase - metabolism | Malondialdehyde - metabolism | Rats, Inbred SHR | Angiotensin II - pharmacology | Rats | Renin-Angiotensin System - physiology | Angiotensin II - analogs & derivatives | Antihypertensive Agents - therapeutic use | Hypertension - physiopathology | Hypertension - metabolism | Animals | Renin-Angiotensin System - drug effects | Peptide Fragments - therapeutic use | Oxidative Stress - drug effects | Nitric Oxide Synthase Type II - metabolism | Hypertension | Neurons | Angiotensin | Apoptosis | Index Medicus
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5. Full Text Effects of S‐1‐propenylcysteine, a sulfur compound in aged garlic extract, on blood pressure and peripheral circulation in spontaneously hypertensive rats
by Ushijima, Mitsuyasu and Takashima, Miyuki and Kunimura, Kayo and Kodera, Yukihiro and Morihara, Naoaki and Tamura, Koichi
Journal of pharmacy and pharmacology, ISSN 0022-3573, 04/2018, Volume 70, Issue 4, pp. 559 - 565
peripheral circulation | hypertension | spontaneously hypertensive rats | aged garlic extract | S‐1‐propenylcysteine | S-1-propenylcysteine | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Hypertension | Sulfur compounds | Blood pressure | Sulfur | Peripheral circulation | Pressure effects | Oral administration | Rats | Blood | Blood flow | Blood circulation | Rodents | Garlic | Index Medicus
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6. Full Text A new approach to identifying hypertension-associated genes in the mesenteric artery of spontaneously hypertensive rats and stroke-prone spontaneously hypertensive rats
by Ikawa, Takashi and Watanabe, Yuko and Okuzaki, Daisuke and Goto, Naohisa and Okamura, Nobutaka and Yamanishi, Kyosuke and Higashino, Toshihide and Yamanishi, Hiromichi and Okamura, Haruki and Higashino, Hideaki
Journal of hypertension, ISSN 0263-6352, 08/2019, Volume 37, Issue 8, pp. 1644 - 1656
Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Index Medicus | DNA microarray | ORIGINAL PAPERS | stroke-prone spontaneously hypertensive rat | spontaneously hypertensive rat | gene expression profile | Experimental hypertension | hypertension | two kidneys and one clip renal hypertensive rat, one kidney and one clip renal hypertensive rat | mesenteric artery
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7. Full Text Effects of Metabolites Produced from (−)-Epigallocatechin Gallate by Rat Intestinal Bacteria on Angiotensin I‑Converting Enzyme Activity and Blood Pressure in Spontaneously Hypertensive Rats
by Takagaki, Akiko and Nanjo, Fumio
Journal of agricultural and food chemistry, ISSN 0021-8561, 09/2015, Volume 63, Issue 37, pp. 8262 - 8266
angiotensin I-converting enzyme | blood pressure | intestinal bacteria | metabolite | epigallocatechin gallate | spontaneously hypertensive rat | valerolactone | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Applied | Food Science & Technology | Agriculture, Multidisciplinary | Agriculture | Science & Technology | Rats, Inbred SHR | Antihypertensive Agents - pharmacology | Bacteria - metabolism | Antihypertensive Agents - urine | Rats | Hypertension - drug therapy | Male | Valerates - metabolism | Catechin - urine | Antihypertensive Agents - metabolism | Lactones - metabolism | Valerates - pharmacology | Lactones - pharmacology | Animals | Intestines - microbiology | Angiotensin-Converting Enzyme Inhibitors - pharmacology | Blood Pressure - drug effects | Catechin - analogs & derivatives | Catechin - metabolism | Catechin - pharmacology | Tea - chemistry | Index Medicus
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8. Full Text Antihypertensive effects of orally administered eggplant (Solanum melongena) rich in acetylcholine on spontaneously hypertensive rats
by Yamaguchi, Shohei and Matsumoto, Kento and Koyama, Masahiro and Tian, Su and Watanabe, Masanori and Takahashi, Akihiko and Miyatake, Koji and Nakamura, Kozo
Food chemistry, ISSN 0308-8146, 03/2019, Volume 276, pp. 376 - 382
Spontaneously hypertensive rats | Acetylcholine | Blood pressure | Eggplant | Catecholamine | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Applied | Nutrition & Dietetics | Food Science & Technology | Science & Technology | Rats, Inbred SHR | Antihypertensive Agents - pharmacology | Animals | Solanum melongena - chemistry | Acetylcholine - pharmacology | Administration, Oral | Rats | Hypertension - drug therapy | Male | Hypertension | Blood vessels | Safety and security measures | Dilatation | Food | Index Medicus
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9. Full Text Kv7(KCNQ)-K+-Channels influence total peripheral resistance in female but not male rats, and hamper catecholamine release in hypertensive rats of both sexes
by Berg, Torill
Frontiers in physiology, ISSN 1664-042X, 02/2018, Volume 9, pp. 117 - 117
Hypertension | channels | Total peripheral vascular resistance | Kv7(KCNQ)-K | Catecholamines | Female | Spontaneously hypertensive rats | Gender | Life Sciences & Biomedicine | Physiology | Science & Technology | Physiological aspects | Genetic aspects | Research | Potassium channels | catecholamines | gender | female | Kv7(KCNQ)-K+-channels | spontaneously hypertensive rats | total peripheral vascular resistance
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10. Full Text Alamandine attenuates hypertension and cardiac hypertrophy in hypertensive rats
by Liu, Chi and Yang, Chuan-Xi and Chen, Xi-Ru and Liu, Bo-Xun and Li, Yong and Wang, Xiao-Zhi and Sun, Wei and Li, Peng and Kong, Xiang-Qing
Amino acids, ISSN 0939-4451, 8/2018, Volume 50, Issue 8, pp. 1071 - 1081
Life Sciences | Biochemistry, general | Hypertension | Protein kinase A | Alamandine | Analytical Chemistry | Life Sciences, general | Biochemical Engineering | Proteomics | Neurobiology | Cardiac hypertrophy | Spontaneously hypertensive rats | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Rats, Inbred SHR | Cell Line | Antihypertensive Agents - pharmacology | Echocardiography | Angiotensins - pharmacology | Cardiomegaly - diagnostic imaging | Cardiomegaly - drug therapy | Antihypertensive Agents - administration & dosage | Rats | Hypertension - drug therapy | Male | Receptors, G-Protein-Coupled - biosynthesis | Heart Ventricles - diagnostic imaging | Rats, Sprague-Dawley | Infusions, Subcutaneous | Animals | Myocytes, Cardiac - drug effects | Heart Ventricles - physiopathology | Injections, Subcutaneous | Nerve Tissue Proteins - biosynthesis | Oligopeptides - administration & dosage | Cyclic AMP-Dependent Protein Kinases - antagonists & inhibitors | Oligopeptides - pharmacology | Measurement | Heart | RNA | Heart enlargement | Blood pressure | G proteins | Protein kinases | Membrane proteins | Cardiovascular agents | Natriuretic peptides | Neonates | Brain | Peptides | Ventricles (cerebral) | Atrial natriuretic peptide | mRNA | Kinases | Proteins | Infusion | Rodents | Attenuation | Inhibition | Angiotensin II | Brain natriuretic peptide | Oral administration | Cardiomyocytes | Gene expression | Fibrosis | Angiotensin | Pressure measurement | Ventricle | Hypertrophy | Index Medicus | Original
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11. Full Text Angiotensin-I converting enzyme inhibitory peptides from antihypertensive skate (Okamejei kenojei) skin gelatin hydrolysate in spontaneously hypertensive rats
by Ngo, Dai-Hung and Kang, Kyong-Hwa and Ryu, BoMi and Vo, Thanh-Sang and Jung, Won-Kyo and Byun, Hee-Guk and Kim, Se-Kwon
Food chemistry, ISSN 0308-8146, 05/2015, Volume 174, pp. 37 - 43
Antihypertension | Spontaneously hypertensive rats | PPAR-γ-eNOS | Angiotensin converting enzyme inhibition | Skate peptides | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Applied | Nutrition & Dietetics | Food Science & Technology | Science & Technology | Rats, Inbred SHR | Fish Proteins - chemistry | Peptides - chemistry | Humans | Subtilisins - chemistry | Antihypertensive Agents - administration & dosage | Rats | Hypertension - drug therapy | Male | Angiotensin-Converting Enzyme Inhibitors - administration & dosage | Vasoconstriction - drug effects | Peptides - administration & dosage | Angiotensin-Converting Enzyme Inhibitors - chemistry | Hydrolysis | Antihypertensive Agents - chemistry | Skin - chemistry | Animals | Skates (Fish) | Peptidyl-Dipeptidase A - metabolism | Female | Blood Pressure - drug effects | Hypertension - enzymology | Gelatin - chemistry | Hypertension | Antihypertensive drugs | Skin | Angiotensin | Index Medicus
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12. Full Text Creatine kinase inhibition lowers systemic arterial blood pressure in spontaneously hypertensive rats: a randomized controlled trial
by Karamat, Fares A and Oudman, Inge and Haan, Yentl C and van Kuilenburg, Ane B. P and Leen, Rene and Danser, Jan A. H and Leijten, Frank P. J and Ris-Stalpers, Carrie and van Montfrans, Gert A and Clark, Joseph F and Brewster, Lizzy M
Journal of hypertension, ISSN 0263-6352, 2016, Volume 34, Issue 12, pp. 2418 - 2426
Hypertension | Spontaneously hypertensive rat | Creatine kinase | Antihypertensive treatment | Blood pressure | Drug development | Betaguanidinopropionic acid | Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Creatine Kinase - antagonists & inhibitors | Propionates - pharmacology | Rats, Inbred SHR | Renin - metabolism | Rats | Guanidines - pharmacology | Hypertension - drug therapy | Male | Arteries - drug effects | Random Allocation | Diuresis - drug effects | Kidney - metabolism | Animals | Arteries - physiopathology | Blood Pressure - drug effects | Protein Kinase Inhibitors - pharmacology | Vasodilation - drug effects | Index Medicus
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