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1. Full Text Molecular Origins of Cancer: Molecular Basis of Colorectal Cancer
by Markowitz, SD and Bertagnolli, MM
NEW ENGLAND JOURNAL OF MEDICINE, ISSN 0028-4793, 12/2009, Volume 361, Issue 25, pp. 2449 - 2460
ISLAND METHYLATOR PHENOTYPE | ADJUVANT CHEMOTHERAPY | MEDICINE, GENERAL & INTERNAL | SPORADIC COLON-CANCER | FECAL OCCULT BLOOD | P53 GENE-MUTATIONS | GERMLINE MUTATIONS | 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE | FACTOR-BETA RECEPTOR | MICROSATELLITE-INSTABILITY | GENOME-WIDE ASSOCIATION | DNA Methylation | Genetic Predisposition to Disease | Colorectal Neoplasms - genetics | DNA Repair | Genes, Tumor Suppressor - physiology | Humans | Signal Transduction - genetics | Mutation | Genome | Oncogenes - physiology | Biomarkers, Tumor | Colorectal Neoplasms - diagnosis
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2. Full Text Role of the Serrated Pathway in Colorectal Cancer Pathogenesis
by Leggett, Barbara and Whitehall, Vicki
Gastroenterology, ISSN 0016-5085, 2010, Volume 138, Issue 6, pp. 2088 - 2100
The “serrated neoplastic pathway” describes the progression of serrated polyps, including sessile serrated adenomas and traditional serrated adenomas, to... 
Gastroenterology and Hepatology | Colorectal Cancer | Hyperplastic Polyposis | Serrated Polyp | SPORADIC COLON-CANCER | DNA METHYLATION | MICROSATELLITE INSTABILITY | BRAF V600E MUTATION | PROMOTER POLYMORPHISM | ISLAND METHYLATOR PHENOTYPE | KRAS MUTATIONS | LOW CIMP-LOW | GASTROENTEROLOGY & HEPATOLOGY | ABERRANT CRYPT FOCI | Predictive Value of Tests | Microsatellite Instability | Prognosis | Adenoma - genetics | Colonic Polyps - pathology | Colorectal Neoplasms - genetics | Humans | Gene Expression Regulation, Neoplastic | Adenoma - therapy | Colonic Polyps - genetics | Cell Transformation, Neoplastic - genetics | Colonoscopy | Precancerous Conditions - pathology | Genetic Predisposition to Disease | Precancerous Conditions - therapy | Risk Assessment | Risk Factors | Colorectal Neoplasms - prevention & control | Precancerous Conditions - genetics | Animals | Biopsy | Adenoma - pathology | Mutation | Cell Transformation, Neoplastic - pathology | Colonic Polyps - therapy | Colorectal Neoplasms - pathology | Development and progression | Protein kinases | Colorectal cancer | Protein binding
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3. Full Text Animal models of colorectal cancer
by Johnson, Robert L and Johnson, Robert L and Fleet, James C and Fleet, James C
Cancer and Metastasis Reviews, ISSN 0167-7659, 6/2013, Volume 32, Issue 1, pp. 39 - 61
Colorectal cancer is a heterogeneous disease that afflicts a large number of people in the USA. The use of animal models has the potential to increase our... 
Genetically modified mice | Biomedicine | Heritable | Sporadic | Chemically induced | Cancer Research | Oncology | Biomedicine general | METHYL-N-NITROSOUREA | BETA-CATENIN GENE | ONCOGENIC K-RAS | MULTIPLE INTESTINAL NEOPLASIA | INDUCED COLON CARCINOGENESIS | TETRACYCLINE-RESPONSIVE PROMOTER | ONCOLOGY | TUMOR-SUPPRESSOR PROTEIN | FAMILIAL ADENOMATOUS POLYPOSIS | ABERRANT CRYPT FOCI | WESTERN-STYLE DIET | Colorectal Neoplasms - etiology | Neoplasm Metastasis | Phenotype | Animals | Humans | Colorectal Neoplasms - pathology | Disease Models, Animal | Prevention | Models | Analysis | Genetically modified organisms | Colorectal cancer | Index Medicus | sporadic | heritable | chemically-induced | genetically modified mice
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4. Full Text Systematic Review of Microsatellite Instability and Colorectal Cancer Prognosis
by S. Popat and R. Hubner and R.S. Houlston
Journal of Clinical Oncology, ISSN 0732-183X, 01/2005, Volume 23, Issue 3, pp. 609 - 618
Purpose A number of studies have investigated the relationship between microsatellite instability (MSI) and colorectal cancer (CRC) prognosis. Although many... 
REPLICATION ERROR PHENOTYPE | SPORADIC-COLON-CANCER | SURVIVAL BENEFIT | ONCOLOGY | DUKES-B | PLUS LEVAMISOLE | CLINICOPATHOLOGICAL VARIABLES | YOUNG-PATIENTS | POSTOPERATIVE ADJUVANT THERAPY | CHEMOTHERAPY | STAGE-II | Prognosis | Colorectal Neoplasms - genetics | Humans | Survival Analysis | Retrospective Studies | Genetic Markers | Colorectal Neoplasms - pathology | Microsatellite Repeats
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5. Full Text Inflammation and Colorectal Cancer
by Long, Apple G and Lundsmith, Emma T and Hamilton, Kathryn E
Current Colorectal Cancer Reports, ISSN 1556-3790, 8/2017, Volume 13, Issue 4, pp. 341 - 351
Colorectal cancer (CRC) is the fourth most common cancer in both men and women in the USA, resulting in over 55,000 deaths annually. Environmental and genetic... 
Colitis-associated cancer | Cytokines | Oncology | Inflammation | Inflammatory bowel disease | Colonoids | Tumoroids | Medicine & Public Health | Colorectal Surgery | Sporadic colorectal cancer | Enteroids | Mouse models of colorectal cancer | Proctology | Medical colleges | Colitis | Gastrointestinal diseases | Analysis | Colorectal cancer | mouse models of colorectal cancer | inflammation | enteroids | cytokines | sporadic colorectal cancer | inflammatory bowel disease | colitis-associated cancer | colonoids | tumoroids
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6. Full Text Classification of colorectal cancer based on correlation of clinical, morphological and molecular features
by Jass, J R
Histopathology, ISSN 0309-0167, 01/2007, Volume 50, Issue 1, pp. 113 - 130
Over the last 20 years it has become clear that colorectal cancer (CRC) evolves through multiple pathways. These pathways may be defined on the basis of two... 
DNA methylation | microsatellite instability | cancer | pathways | classification | colorectal | Colorectal | Microsatellite instability | Pathways | Classification | Cancer | HYPERPLASTIC POLYPS | DNA MICROSATELLITE INSTABILITY | SPORADIC COLON-CANCER | SERRATED ADENOMAS | ADENOMA-CARCINOMA SEQUENCE | MISMATCH REPAIR | PATHOLOGY | BETA-CATENIN MUTATIONS | CELL BIOLOGY | ISLAND METHYLATOR PHENOTYPE | TUMOR-INFILTRATING LYMPHOCYTES | K-RAS MUTATION | Microsatellite Instability | Adenocarcinoma - pathology | Adenocarcinoma - classification | Colorectal Neoplasms - genetics | Humans | Colorectal Neoplasms - classification | Precancerous Conditions - genetics | DNA Methylation | CpG Islands - genetics | Precancerous Conditions - pathology | Adenocarcinoma - genetics | DNA, Neoplasm - analysis | Mutation | Colorectal Neoplasms - pathology | Colorectal cancer
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7. Full Text 5-Fluorouracil Adjuvant Chemotherapy Does Not Increase Survival in Patients With CpG Island Methylator Phenotype Colorectal Cancer
by Jover, Rodrigo and Nguyen, Thuy–Phuong and Pérez–Carbonell, Lucía and Zapater, Pedro and Payá, Artemio and Alenda, Cristina and Rojas, Estefanía and Cubiella, Joaquín and Balaguer, Francesc and Morillas, Juan D and Clofent, Juan and Bujanda, Luis and Reñé, Josep M and Bessa, Xavier and Xicola, Rosa M and Nicolás–Pérez, David and Castells, Antoni and Andreu, Montserrat and Llor, Xavier and Boland, C. Richard and Goel, Ajay
Gastroenterology, ISSN 0016-5085, 2011, Volume 140, Issue 4, pp. 1174 - 1181
Background & Aims 5-Fluorouracil (5-FU)–based adjuvant chemotherapy does not increase survival times of patients with colorectal tumors with microsatellite... 
Gastroenterology and Hepatology | 5-FU Adjuvant Chemotherapy | DNA Methylation | Response to Cancer Therapy | Colon Cancer | PREDICTOR | SPORADIC COLON-CANCER | EFFICACY | PROGNOSIS | MISMATCH REPAIR STATUS | MICROSATELLITE-INSTABILITY | BENEFIT | BRAF MUTATION | GASTROENTEROLOGY & HEPATOLOGY | ASSOCIATION | EXPRESSION | Colorectal Neoplasms - mortality | Predictive Value of Tests | Prognosis | Follow-Up Studies | Colorectal Neoplasms - genetics | Humans | Middle Aged | Kaplan-Meier Estimate | Proportional Hazards Models | Male | CpG Islands - physiology | Antimetabolites, Antineoplastic - administration & dosage | Disease-Free Survival | Phenotype | Fluorouracil - administration & dosage | Chemotherapy, Adjuvant - methods | Colorectal Neoplasms - drug therapy | Aged, 80 and over | Female | Aged | Cohort Studies | DNA methylation | response to cancer therapy | Colon cancer | 5-FU adjuvant chemotherapy
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8. Full Text Chemotherapy of MMR-deficient colorectal cancer
by Devaud, N and Gallinger, S
Familial Cancer, ISSN 1389-9600, 6/2013, Volume 12, Issue 2, pp. 301 - 306
Colorectal cancer (CRC) continues to rank as the third most common cancer in Western society and the second leading cause of cancer death in North America.... 
Human Genetics | Microsatellite Instability | Chemotherapy | Biomedicine | Colorectal cancer | Cancer Research | Epidemiology | Biomedicine general | LEUCOVORIN | SURGICAL ADJUVANT BREAST | SPORADIC COLON-CANCER | OXALIPLATIN | FLUOROURACIL | STAGE-II | TUMOR MICROSATELLITE-INSTABILITY | DNA MISMATCH REPAIR | 5-FLUOROURACIL | ONCOLOGY | GENETICS & HEREDITY | MUTATIONS | Drug Resistance, Neoplasm - genetics | Colorectal Neoplasms - drug therapy | Colorectal Neoplasms - genetics | DNA Mismatch Repair | Humans | Antineoplastic Agents - therapeutic use | Cancer
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9. Full Text Four molecular subtypes of colorectal cancer and their precursor lesions
by Kang, Gyeong Hoon
Archives of Pathology and Laboratory Medicine, ISSN 0003-9985, 06/2011, Volume 135, Issue 6, pp. 698 - 703
Context.-In addition to chromosomal instability and microsatellite instability (MSI), a third pathway, epigenetic instability, has been implicated in... 
MEDICINE, RESEARCH & EXPERIMENTAL | SPORADIC COLON-CANCER | MICROSATELLITE INSTABILITY | LYNCH SYNDROME | PATHOLOGY | ISLAND METHYLATOR PHENOTYPE | DNA MISMATCH REPAIR | POPULATION-BASED SAMPLE | SERRATED POLYPS | MUTATION | MEDICAL LABORATORY TECHNOLOGY | CLINICOPATHOLOGICAL FEATURES | CPG-ISLANDS | Microsatellite Instability | Adenoma - genetics | Adenoma - mortality | Colorectal Neoplasms - genetics | Epigenesis, Genetic | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Male | Biomarkers, Tumor | Colorectal Neoplasms - diagnosis | Precancerous Conditions - diagnosis | Precancerous Conditions - mortality | Female | Adenocarcinoma - genetics | Korea - epidemiology | Colorectal Neoplasms - mortality | Adenoma - diagnosis | Gene Silencing | Survival Rate | Precancerous Conditions - genetics | Adenocarcinoma - diagnosis | Proto-Oncogene Proteins B-raf - genetics | CpG Islands - genetics | Aged | Mutation | Adenocarcinoma - mortality | Colorectal cancer | Tumors
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10. Full Text Dairy foods, calcium, and colorectal cancer: a pooled analysis of 10 cohort studies
by Cho, E and Smith-Warner, S.A and Spiegelman, D and Beeson, W.L and van den Brandt, P.A and Colditz, G.A and Folsom, A.R and Fraser, G.E and Freudenheim, J.L and Giovannucci, E and Goldbohm, R.A and Graham, S and Miller, A.B and Pietinen, P and Potter, J.D and Rohan, T.E and Terry, P and Toniolo, P and Virtanen, M.J and Willett, W.C and Wolk, A and Wu, K and Yaun, S.S and Zeleniuch Jacquotte, A and Hunter, D.J
Journal of the National Cancer Institute, ISSN 0027-8874, 01/2004, Volume 96, Issue 13, pp. 1015 - 22
Background. Studies in animals have suggested that calcium may reduce the risk of colorectal cancer. However, results from epidemiologic studies of intake of... 
COLON-CANCER | BREAST-CANCER | EPITHELIAL-CELL PROLIFERATION | VITAMIN-D | DIETARY CALCIUM | ONCOLOGY | FREQUENCY QUESTIONNAIRE | OLDER WOMEN | RANDOMIZED CONTROLLED-TRIAL | SPORADIC ADENOMA | WOMENS HEALTH | Multivariate Analysis | United States - epidemiology | Prospective Studies | Adenoma - epidemiology | Humans | Middle Aged | Adenoma - prevention & control | Male | Incidence | Calcium, Dietary - administration & dosage | Adult | Female | Surveys and Questionnaires | Milk | Colorectal Neoplasms - epidemiology | Eating | Risk Assessment | Risk Factors | Proportional Hazards Models | Colorectal Neoplasms - prevention & control | Europe - epidemiology | Animals | Dairy Products - statistics & numerical data | Aged | Research Design | Cohort Studies | Case studies | Control | Calcium, Dietary | Colorectal cancer | Influence | Risk factors
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11.