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Autophagy, ISSN 1554-8627, 2013, Volume 9, Issue 10, pp. 1500 - 1508
Journal Article
Journal of molecular biology, ISSN 0022-2836, 06/2019
Cells are constantly challenged by endogenous and exogenous stress sources. To cope with them, organisms have developed a series of defensive mechanisms to... 
Journal Article
Autophagy, ISSN 1554-8627, 04/2019, Volume 15, Issue 4, pp. 583 - 598
Accumulating evidence suggests that misfolded MAPT (microtubule associated protein tau), the main component of neurofibrillary tangles in tauopathies, is... 
tauopathy | Alzheimer disease | mice | SQSTM1 | selective autophagy | PHOSPHORYLATION | ALZHEIMERS-DISEASE | P62/SQSTM1 | NEURODEGENERATION | OPTINEURIN | P62 | CELL BIOLOGY | MOUSE MODEL | AUTOPHAGIC CLEARANCE | DEGRADATION | HUNTINGTONS-DISEASE
Journal Article
Oncotarget, ISSN 1949-2553, 11/2018, Volume 9, Issue 88, pp. 35830 - 35843
Phosphorylation of p62/SQSTM1 (p62) on Serine 349 (P-Ser349 p62) as well as proteasome dysfunction have been shown to activate the cell protective Keap1/Nrf2... 
P62/SQSTM1 phosphorylation | Serum starvation | Autophagy | RAD23B | Proteasome
Journal Article
Autophagy, ISSN 1554-8627, 04/2019, Volume 15, Issue 4, pp. 652 - 667
EBV has been reported to impair monocyte in vitro differentiation into dendritic cells (DCs) and reduce cell survival. In this study, we added another layer of... 
monocytes | SQSTM1/p62 | autophagy | dendritic cells | ROS | STAT3 | EBV | ATG5 | NFE2L2 | ACTIVATION | PHOSPHORYLATION | TRANSCRIPTION | p62 | CANCER | CELL BIOLOGY | NRF2 | BIOGENESIS | INFECTION | SQSTM1 | EPSTEIN-BARR-VIRUS
Journal Article
Journal of Virology, ISSN 0022-538X, 01/2019, Volume 93, Issue 2
The existence of the antisense transcript-encoded HIV-1 antisense protein (ASP) was recently reinforced by in silico analyses providing evidence for recent... 
HIV-1 | Ubiquitination | Multimerization | P62/SQSTM1 | Clade | Autophagy | Antisense protein | CELLS | autophagy | RECOGNITION | UBIQUITIN | p62/SQSTM1 | HUMAN-IMMUNODEFICIENCY-VIRUS | IDENTIFICATION | multimerization | antisense protein | VIROLOGY | BECLIN-1 | GENE | ubiquitination | INTERACTS | INFECTION | clade | INSIGHTS
Journal Article
Autophagy, ISSN 1554-8627, 12/2014, Volume 10, Issue 12, pp. 2333 - 2345
The hypoxia inducible transcription factor HIF1 activates autophagy, a general catabolic pathway involved in the maintenance of cellular homeostasis.... 
SQSTM1/p62 (SQSTM1), sequestosome 1 | HIF1A, hypoxia inducible factor 1, α subunit (basic helix-loop-helix transcription factor) | bacteria | hypoxia inducible factor | AMPK, AMP-activated protein kinase | CRTC1/TORC1, CREB regulated transcription coactivator 1 | EEA1, early endosome antigen 1 | HBSS, Hank's balanced salt solution | TLR5, toll-like receptor 5 | ULK1, unc-51 like autophagy activating kinase 1 | AIEC, adherent invasive E. coli | ATG5, autophagy-related 5 | ATG16L1, autophagy-related 16-like 1 | CD, Crohn disease | MAP1LC3-II (LC3-II), microtubule-associated protein 1 light chain 3-II | CEACAM6, carcinoembryonic antigen-related cell adhesion molecule 6 (nonspecific cross reacting antigen) | LAP, LC3-associated phagocytosis | GFP, green fluorescent protein | autophagy | IRGM, immunity-related GTPase family, M | BECN1, Beclin 1, autophagy-related | TEM, transmission electron microscopy | Crohn disease | VAV2, vav 2 guanine nucleotide exchange factor | BNIP3L, BCL2/adenovirus E1B 19kDa interacting protein 3-like | MOI, multiplicity of infection | IBD, inflammatory bowel disease | LAP | Bacteria | Hypoxia inducible factor | Autophagy | IMPAIRED AUTOPHAGY | STRAIN LF82 | PROTEIN | CROHNS-DISEASE | MACROPHAGES | HYPOXIA-INDUCIBLE FACTORS | E. COLI | CELL BIOLOGY | ILEAL MUCOSA | ULK1 | TYPE-1 PILI | Cell Line | Intestinal Mucosa - metabolism | Epithelial Cells - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Epithelial Cells - microbiology | Humans | Crohn Disease - metabolism | Autophagy - physiology | Escherichia coli Infections - metabolism | Crohn Disease - immunology
Journal Article
Journal of cell science, ISSN 0021-9533, 11/2018, Volume 131, Issue 21, p. jcs222836
SQSTM1 (also known as p62) is a multifunctional stress-inducible scaffold protein involved in diverse cellular processes. Its functions are tightly regulated... 
Sqstm1 | Selective autophagy | Keap1–Nrf2 system | p62 | Proteinopathies | Phase separation | SUBCELLULAR-LOCALIZATION | SQSTM1/P62 CONTRIBUTES | CISPLATIN RESISTANCE | Keap1-Nrf2 system | PAGET-DISEASE | SELECTIVE AUTOPHAGY SUBSTRATE | CELL BIOLOGY | UBA DOMAIN | HEPATOCELLULAR-CARCINOMA | TRANSCRIPTION FACTOR NRF2 | INTERACTING PROTEIN P62 | ADIPOSE-TISSUE
Journal Article
Bone, ISSN 8756-3282, 11/2019, Volume 128, p. 115044
Familial Paget's disease of bone is inherited as an autosomal-dominant trait and mutations in the ( ) gene have been reported with variable frequency in... 
SQSTM1 | Familial | Paget's disease of bone | Follow-up
Journal Article
Journal Article
Autophagy, ISSN 1554-8627, 04/2019, Volume 15, Issue 4, pp. 738 - 739
In the tumor stroma, cancer-associated fibroblasts (CAFs) affect all aspects of tumor evolution. Whereas several programs leading to CAF activation have been... 
protein turnover | SQSTM1/p62 | CSL/RBP-Jκ | tumor stroma | CAF (cancer-associated fibroblast) | RBP-J kappa | CSL | SQSTM1 | p62 | CELL BIOLOGY
Journal Article