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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2010, Volume 107, Issue 50, pp. 21337 - 21342
Journal Article
Planta, ISSN 0032-0935, 07/2017, Volume 246, Issue 1, pp. 45 - 60
Main conclusion The use of a VIGS approach to silence the newly characterized apple tree SQS isoforms points out the biological function of phytosterols in... 
Apple tree | Apple latent spherical virus (ALSV) | Squalene synthase | Phytosterol | Triterpene | VIGS | STEROL BIOSYNTHESIS | SAPONIN BIOSYNTHESIS | LANOSTEROL SYNTHASE | CDNA | OXIDOSQUALENE CYCLASES | PLANT SCIENCES | FUNCTIONAL EXPRESSION | PLANT STEROLS | MOLECULAR-CLONING | ARABIDOPSIS | Farnesyl-Diphosphate Farnesyltransferase - genetics | Gene Expression Regulation, Plant - genetics | Malus - growth & development | Malus - genetics | Farnesyl-Diphosphate Farnesyltransferase - metabolism | Phytosterols - biosynthesis | Secoviridae - genetics | Malus - metabolism | Protein Isoforms - metabolism | Plant Leaves - genetics | Plant Leaves - metabolism | Plant Leaves - growth & development | Gene Expression Regulation, Plant - physiology | Plastids - metabolism | Triterpenes - metabolism | Gene Silencing - physiology | Protein Isoforms - genetics | RNA sequencing | Enzymes | Analysis | Genes | Phytosterols | Genetic research | Physiological aspects | Genetic engineering | Triterpenoids | Viruses | Genomes | Biosynthesis | Fruit trees | Assaying | Leaves | Metabolic flux | Pathways | Elongation | Trees | Plants (botany) | Fluctuations | Organs | Squalene | Flux | Light emitting diodes | Metabolism | Pigmentation | Gene silencing | Silence | Isoforms | Metabolic pathways | Differentiation | In vitro methods and tests | Endoplasmic reticulum | Integrity | Life Sciences
Journal Article
Journal Article
PLoS Pathogens, ISSN 1553-7366, 2014, Volume 10, Issue 5, p. e1004114
Trypanosomatid parasites are the causative agents of many neglected tropical diseases and there is currently considerable interest in targeting endogenous... 
MECHANISM | NITROGEN-CONTAINING BISPHOSPHONATES | TRYPANOSOMA-CRUZI | MICROBIOLOGY | CRYSTALLOGRAPHY | MODEL | FARNESYL DIPHOSPHATE SYNTHASE | IN-VITRO | VIROLOGY | ISOPRENOID BIOSYNTHESIS | INHIBITORS | CHOLESTEROL-BIOSYNTHESIS | PARASITOLOGY | Polyisoprenyl Phosphates - chemistry | Sesquiterpenes - metabolism | Humans | Cercopithecus aethiops | Crystallography, X-Ray | Trypanocidal Agents - chemistry | Trypanosoma cruzi - enzymology | Farnesyl-Diphosphate Farnesyltransferase - chemistry | Enzyme Inhibitors - chemistry | Trypanocidal Agents - therapeutic use | Vero Cells | Molecular Targeted Therapy - methods | Trypanocidal Agents - metabolism | Sesquiterpenes - chemistry | Enzyme Inhibitors - metabolism | Quinuclidines - pharmacology | Enzyme Inhibitors - pharmacology | Models, Molecular | Diphosphonates - metabolism | Enzyme Inhibitors - therapeutic use | Polyisoprenyl Phosphates - metabolism | Farnesyl-Diphosphate Farnesyltransferase - metabolism | Animals | Trypanocidal Agents - pharmacology | Farnesyl-Diphosphate Farnesyltransferase - antagonists & inhibitors | Diphosphonates - chemistry | Chagas Disease - drug therapy | Protein Binding | Quinuclidines - chemistry | Quinuclidines - metabolism | Diphosphonates - pharmacology | Phosphonates | Physiological aspects | Squalene | Chagas' disease | Diagnosis | Research | Drug therapy | Health aspects | Research & development | Protozoa | R&D | Disease | Sterols | Ligands | Biosynthesis | Parasites | Tropical diseases | Cholesterol
Journal Article
Current Science, ISSN 0011-3891, 2017, Volume 113, Issue 4, pp. 785 - 790
Farnesyl diphosphate synthase (FPS) is a key enzyme in isoprenoid biosynthesis, generating farnesyl diphosphate as the central precursor for the broad classes... 
Farnesyl diphosphate synthase | Fusion protein | Squalene synthase | Triterpenoids | CHOLESTEROL | triterpenoids | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | FARNESYLDIPHOSPHATE SYNTHASE | SACCHAROMYCES-CEREVISIAE | squalene synthase | fusion protein | GENE | METABOLISM | CLONING | ENZYMES | PHYTOSTEROL | EXPRESSION
Journal Article
Journal Article
Plant and Cell Physiology, ISSN 0032-0781, 03/2016, Volume 57, Issue 3, pp. 588 - 602
Journal Article
Journal Article