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chemistry, organic (148) 148
derivatives (111) 111
catalysis (94) 94
squaramide (91) 91
organocatalysis (83) 83
chemistry, multidisciplinary (79) 79
michael addition (75) 75
squaramides (75) 75
index medicus (62) 62
conjugate addition (58) 58
1,3-dicarbonyl compounds (45) 45
asymmetric catalysis (45) 45
catalysts (42) 42
enantiomers (41) 41
squaramide derivatives (41) 41
construction (37) 37
synthesis (34) 34
stereoisomerism (32) 32
chemistry, applied (31) 31
chiral squaramides (29) 29
enantioselective michael addition (29) 29
hydrogen bonding (28) 28
asymmetric-synthesis (27) 27
enantioselective synthesis (27) 27
molecular structure (26) 26
organocatalysts (25) 25
aldehydes (24) 24
nitroalkenes (23) 23
receptors (22) 22
asymmetry (21) 21
binding (21) 21
ketones (21) 21
nitroalkanes (21) 21
thiourea (20) 20
michael reaction (19) 19
urea (19) 19
hydrogen (18) 18
molecular recognition (18) 18
organic chemistry (18) 18
cascade reaction (17) 17
chemistry (17) 17
recognition (17) 17
asymmetric michael addition (16) 16
chiral squaramide (16) 16
design (16) 16
squaric acid (16) 16
chemistry, physical (15) 15
domino reactions (15) 15
esters (15) 15
amides - chemistry (14) 14
efficient (14) 14
nitroolefins (14) 14
anions (13) 13
asymmetric synthesis (13) 13
bifunctional organocatalysts (13) 13
inhibitors (13) 13
acid (12) 12
activation (12) 12
alkaloids (12) 12
cascade reactions (12) 12
chemical synthesis (12) 12
highly efficient (12) 12
hydrogen bonds (12) 12
organic compounds (12) 12
analysis (11) 11
asymmetric organocatalysis (11) 11
asymmetrische katalyse (11) 11
chemistry, medicinal (11) 11
cyclization (11) 11
enantio-selectivity (11) 11
enantioselektivität (11) 11
quinine - analogs & derivatives (11) 11
quinine - chemistry (11) 11
aldol reactions (10) 10
anion recognition (10) 10
asymmetric-catalysis (10) 10
dynamic kinetic resolution (10) 10
enantioselectivity (10) 10
michael-addition (10) 10
oxindoles (10) 10
aldol reaction (9) 9
cascade chemical reactions (9) 9
letter (9) 9
models, molecular (9) 9
stereocenters (9) 9
stereoselective-synthesis (9) 9
alpha-keto esters (8) 8
anion (8) 8
bond donors (8) 8
complexes (8) 8
cycloaddition (8) 8
enantioselective construction (8) 8
enantioselective michael-addition (8) 8
heterocycles (8) 8
organocatalyst (8) 8
thiourea - chemistry (8) 8
3 contiguous stereocenters (7) 7
alpha,beta-unsaturated ketones (7) 7
chemical properties (7) 7
cinchonine-squaramide (7) 7
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Advanced synthesis & catalysis, ISSN 1615-4150, 2013, Volume 355, Issue 11-12, pp. 2249 - 2256
...‐isothiocyanatooxindoles with allenic esters or 2‐butynedioic acid diesters has been developed, affording functionalized spirooxindole derivatives in high yields along with good to excellent enantioselectivities under mild conditions... 
allenic esters | asymmetric [3+2] cycloaddition | Cinchona alkaloids | organocatalysts | spirooxindole derivatives | Spirooxindole derivatives | Asymmetric [3+2] cycloaddition | Organocatalysts | Allenic esters | CATALYSIS | PHOSPHINE | DIELS-ALDER REACTIONS | CHEMISTRY, ORGANIC | SQUARAMIDES | QUATERNARY | HIGHLY EFFICIENT | MICHAEL ADDITION | POTENT | STEREOCENTERS | CHEMISTRY, APPLIED | CONJUGATE ADDITION | Esters | Enantiomers | Hydrogen | Fine chemicals | Cycloaddition | Construction | Synthesis | Asymmetry | Diesters | Derivatives | Catalysis
Journal Article
Tetrahedron, ISSN 0040-4020, 2016, Volume 72, Issue 49, pp. 8042 - 8049
...-(1-tosyl-1H-indol-3-yl)ethyl)pentane-2,4-dione derivatives in up to 98% ee using BnCPN as an organocatalyst... 
Enantioselective | DFT | Indolylnitroalkenes | Organocatalysis | Michael addition reaction | ACID | 1,3-DICARBONYL COMPOUNDS | MALONATE | OXINDOLES | CHEMISTRY, ORGANIC | SQUARAMIDE DERIVATIVES | KETONES | ASYMMETRIC MICHAEL ADDITION | NITROALKENES | CATALYSTS | CONJUGATE ADDITION | Enantiomers
Journal Article
New journal of chemistry, ISSN 1369-9261, 2018, Volume 42, Issue 11, pp. 8596 - 8602
.... Three cinchona derivatives have shown remarkable activity to catalyze the aza-Markovnikov addition reaction of N-heterocycles to vinyl esters... 
RECOVERY | ASYMMETRIC-SYNTHESIS | SQUARAMIDE | VINYL ESTERS | MICHAEL-ADDITION | CHEMISTRY | ORGANIC-SOLVENT NANOFILTRATION | CHEMISTRY, MULTIDISCIPLINARY | CATALYSTS | N-HETEROCYCLES | ALKALOIDS | Membrane separation | Regioselectivity | Sustainability | Esters | Vinyl ester resins | Derivatives | Chemical synthesis | Biological activity | Adducts
Journal Article
Periodica Polytechnica Chemical Engineering, ISSN 0324-5853, 11/2018, Volume 62, Issue 4, pp. 467 - 475
Thiosquaramides are the thio analogues of squaramides that are widely applicable in the fields of asymmetric catalysis, pharmaceutical research, and chemical... 
Anion transport | Thiosquaramide | Squaramide | Organocatalysis | Hydrogen bond donors | DESIGN | RECOGNITION | hydrogen bond donors | POLYCARBONYL COMPOUNDS | anion transport | SQUARIC ACID | organocatalysis | ENGINEERING, CHEMICAL | ORGANOCATALYSTS | EQUILIBRIUM ACIDITIES | thiosquaramide | RECEPTORS | squaramide | UREA
Journal Article
Mini-Reviews in Organic Chemistry, ISSN 1570-193X, 04/2018, Volume 15, Issue 2, pp. 148 - 156
...: This paper reviews the recent advance in the synthesis of squaramide derivatives and their applications in the field of anion recognition and transmembrane transport... 
Recognition of sulfate | Anion recognition | Synthesis | Squaramide | Transmembrane anion transport | Hydrogen bond | synthesis | recognition of sulfate | BOND DONOR CATALYSTS | anion recognition | AQUEOUS-MEDIA | CHEMISTRY, ORGANIC | ION TRANSPORTERS | SQUARIC ACID | ANTICANCER ACTIVITY | IN-VITRO | MOLECULAR RECOGNITION | transmembrane anion transport | RECEPTORS | BINDING | hydrogen bond | CHLORIDE
Journal Article
Molecules, ISSN 1420-3049, 12/2014, Volume 19, Issue 12, pp. 19491 - 19500
An effective method has been developed for the preparation of novel chiral chalcone derivatives under mild conditions from the easily accessible starting materials nitromethane and chalcone derivatives 2... 
Chalcone derivatives | Addition reaction | Enantioselective catalysis | Chiral cinchona alkaloid squaramides | ANTIBACTERIAL | CHEMISTRY, ORGANIC | chiral cinchona alkaloid squaramides | addition reaction | chalcone derivatives | enantioselective catalysis | Chalcone - chemistry | Catalysis | Stereoisomerism | Chalcone - chemical synthesis | Cinchona Alkaloids - chemistry
Journal Article
Biomolecules (Basel, Switzerland), ISSN 2218-273X, 2019, Volume 9, Issue 8, p. 379
Tacrine was the first drug to be approved for Alzheimer’s disease (AD) treatment, acting as a cholinesterase inhibitor. The neuropathological hallmarks of AD... 
squaramides | TARGET-DIRECTED LIGANDS | bis-tacrine | ASSAY | 6-chlorotacrine | tacrine | BIOCHEMISTRY & MOLECULAR BIOLOGY | DRUG DESIGN STRATEGY | RECEPTOR | in silico | NEUROPROTECTION | ANTI-ALZHEIMERS DIMER | cholinesterases | in vitro | DISEASE | 7-methoxytacrine | ACETYLCHOLINESTERASE INHIBITORS | Alzheimer's disease | BINDING | Alzheimer’s disease
Journal Article
Chemical communications (Cambridge, England), ISSN 1359-7345, 2012, Volume 48, Issue 42, pp. 5160 - 5162
An efficient organocatalytic Michael-aldol cascade reaction for the asymmetric synthesis of spirocyclic oxindole derivatives fused with tetrahydrothiophenes has been developed through a formal [3 + 2... 
SPIROOXINDOLE NATURAL-PRODUCTS | HIGHLY ENANTIOSELECTIVE SYNTHESIS | SULFUR YLIDES | DIELS-ALDER | MULTIPLE STEREOCENTERS | ADDITION-REACTIONS | PICTET-SPENGLER REACTIONS | CATALYTIC ASYMMETRIC-SYNTHESIS | CHEMISTRY, MULTIDISCIPLINARY | STEREOCONTROLLED SYNTHESIS | SQUARAMIDE DERIVATIVES | Cyclization | Stereoisomerism | Catalysis | Thiophenes - chemistry | Indoles - chemistry | Spiro Compounds - chemistry | Aldehydes - chemistry
Journal Article