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sr-33589 (50) 50
amiodarone - analogs & derivatives (39) 39
dronedarone (33) 33
amiodarone (28) 28
animals (28) 28
heart (27) 27
pharmacology & pharmacy (27) 27
cardiac & cardiovascular systems (26) 26
humans (26) 26
arrhythmias (24) 24
amiodarone - pharmacology (23) 23
index medicus (23) 23
amiodarone-like agent (21) 21
atrial fibrillation (21) 21
male (21) 21
amiodarone - therapeutic use (20) 20
anti-arrhythmia agents - pharmacology (19) 19
anti-arrhythmia agents - therapeutic use (19) 19
antiarrhythmic agent (18) 18
atrial fibrillation - drug therapy (18) 18
atrial-fibrillation (18) 18
sinus rhythm (16) 16
anti-arrhythmia agents - administration & dosage (15) 15
amiodarone - administration & dosage (14) 14
anti-arrhythmia agents - adverse effects (14) 14
female (14) 14
amiodarone - adverse effects (13) 13
heart rate - drug effects (13) 13
dogs (12) 12
adrenoceptor (11) 11
atrial fibrillation - physiopathology (11) 11
ischemia (11) 11
action potentials - drug effects (10) 10
amiodarone - pharmacokinetics (10) 10
anti-arrhythmia agents - pharmacokinetics (10) 10
k+ current (9) 9
mortality (9) 9
cells (8) 8
dose-response relationship, drug (8) 8
drug therapy (8) 8
antiarrhythmic drugs (6) 6
arrhythmia (6) 6
cardiac arrhythmia (6) 6
clinical trials as topic (6) 6
disease models, animal (6) 6
drug interactions (6) 6
electrophysiology (6) 6
maintenance (6) 6
rats (6) 6
therapy (6) 6
amiodarone - chemistry (5) 5
anti-arrhythmia agents - chemistry (5) 5
anti-arrhythmia drugs (5) 5
antiarrhythmic agents (5) 5
atrial flutter - drug therapy (5) 5
blood pressure - drug effects (5) 5
de-pointes arrhythmias (5) 5
double-blind method (5) 5
electrocardiography - drug effects (5) 5
heart - drug effects (5) 5
heart failure (5) 5
heart-failure (5) 5
management (5) 5
myocardial-infarction (5) 5
prevention (5) 5
reperfusion (5) 5
treatment outcome (5) 5
action potentials - physiology (4) 4
administration, oral (4) 4
adult (4) 4
agent (4) 4
efficacy (4) 4
electrocardiography (4) 4
fibrillation (4) 4
guinea pigs (4) 4
hemodynamics - drug effects (4) 4
in vitro techniques (4) 4
injections, intravenous (4) 4
medicine, general & internal (4) 4
pharmacology/toxicology (4) 4
randomized controlled trials as topic (4) 4
rhythm control (4) 4
rhythm-control (4) 4
time factors (4) 4
abridged index medicus (3) 3
aged (3) 3
antiarrhythmic-drugs (3) 3
antiarrhythmics (3) 3
arrhythmias, cardiac - drug therapy (3) 3
atrial fibrillation - prevention & control (3) 3
atrial flutter (3) 3
congestive-heart-failure (3) 3
dog (3) 3
drug therapy, combination (3) 3
drugs (3) 3
evaluation (3) 3
heart conduction system - drug effects (3) 3
heart diseases (3) 3
heart rate (3) 3
heart ventricles - drug effects (3) 3
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The New England Journal of Medicine, ISSN 0028-4793, 12/2011, Volume 365, Issue 24, pp. 2268 - 2276
Patients with permanent atrial fibrillation and additional cardiac risk factors were randomly assigned to receive either dronedarone or placebo. At a median of... 
HEART | ARRHYTHMIAS | MORTALITY | ADRENOCEPTOR | MEDICINE, GENERAL & INTERNAL | FOLLOW-UP | SR-33589 | AMIODARONE-LIKE AGENT | Follow-Up Studies | Humans | Anti-Arrhythmia Agents - blood | Hospitalization - statistics & numerical data | Male | Amiodarone - adverse effects | Heart Rate - drug effects | Stroke - chemically induced | Amiodarone - therapeutic use | Aged, 80 and over | Cardiovascular Diseases - mortality | Female | Stroke - epidemiology | Drug Therapy, Combination | Digoxin - blood | Digoxin - therapeutic use | Heart Failure - epidemiology | Double-Blind Method | Atrial Fibrillation - drug therapy | Risk Factors | Anti-Arrhythmia Agents - therapeutic use | Amiodarone - analogs & derivatives | Atrial Fibrillation - blood | Anti-Arrhythmia Agents - adverse effects | Atrial Flutter - drug therapy | Aged | Cardiovascular Diseases - chemically induced | Chronic Disease | Heart Failure - chemically induced | Drugs | Product/Service Evaluations | Drug therapy | Atrial fibrillation | Heart failure | Myocardial infarction | Cerebral infarction | Cardiac arrhythmia | Medical research | Arrhythmia | Risk groups | Cardiovascular disease | Hospitalization | Embolism | Risk factors | Heart rate | Sinuses | Fibrillation | Death | Blood pressure | Ventricle | Acute coronary syndromes | Heart diseases | Medical and Health Sciences | Medicin och hälsovetenskap
Journal Article
Journal Article
Journal Article
Circulation, ISSN 0009-7322, 05/1999, Volume 99, Issue 17, pp. 2268 - 2275
Background-Investigations with in vitro and animal models suggest an interaction between amiodarone and beta-blockers. The objective of this work was to... 
Myocardial infarction | Trials | Antiarrhythmia agents | CARDIAC & CARDIOVASCULAR SYSTEMS | trials | ADRENOCEPTORS | myocardial infarction | SR-33589 | PERIPHERAL VASCULAR DISEASE | antiarrhythmia agents | HEMATOLOGY
Journal Article
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY, ISSN 1045-3873, 08/2013, Volume 24, Issue 8, pp. 914 - 918
Dronedarone's Bradycardic Effect IntroductionThe mechanism(s) whereby dronedarone reduces sinus rate are not well understood, although L-type calcium channel... 
heart rate | AMIODARONE | CARDIAC & CARDIOVASCULAR SYSTEMS | contractility | PACEMAKER ACTIVITY | NODE | I-f current | hemodynamics | IVABRADINE | ATRIAL-FIBRILLATION | dronedarone | DOGS | SR-33589 | ANTIARRHYTHMIC AGENT
Journal Article
Journal Article
HEART RHYTHM, ISSN 1547-5271, 11/2013, Volume 10, Issue 11, pp. 1692 - 1697
BACKGROUND In clinical trials, dronedarone lowers ventricular rate during atrial fibrillation (AF). This agent was recently demonstrated to inhibit I-f in the... 
Human hyperpolarization-activated cyclic nucleotide-gated (HCN) channel | ARRHYTHMIAS | AMIODARONE | CARDIAC & CARDIOVASCULAR SYSTEMS | Atrial fibrillation | Ivabradine | PACEMAKER ACTIVITY | Dronedarone | HEART | AGENT | I-f inhibition | DOUBLE-BLIND | Atrioventricular node | SR-33589 | ZATEBRADINE | RHYTHM
Journal Article
NATURE REVIEWS DRUG DISCOVERY, ISSN 1474-1776, 10/2009, Volume 8, Issue 10, pp. 769 - 770
Journal Article
Journal Article