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JOURNAL OF CLINICAL INVESTIGATION, ISSN 0021-9738, 08/2014, Volume 124, Issue 8, pp. 3419 - 3430
Mutations in the gene encoding the RNA-binding protein RBM20 have been implicated in dilated cardiomyopathy (DCM), a major cause of chronic heart failure,... 
MEDICINE, RESEARCH & EXPERIMENTAL | ACTIVATION | MESSENGER-RNA | GENE | CA2+ RELEASE | SR PROTEINS | MOUSE MODEL | DILATED CARDIOMYOPATHY | MUTATIONS | IDENTIFICATION | EXPRESSION
Journal Article
06/2012
Diamond Blackfan Anemia (DBA) is a congenital disorder characterized by a specific reduction in erythroid progenitor cells. Approximately 55% of patients have... 
Erythropoiesis | Tra2Beta | FLVCR1 aberrant splicing | SR proteins | RPS19 | Diamond-Blackfan Anemia
Dissertation
Nature Communications, ISSN 2041-1723, 03/2017, Volume 8, Issue 1, pp. 14741 - 14741
The RNA-binding protein FUS participates in several RNA biosynthetic processes and has been linked to the pathogenesis of amyotrophic lateral sclerosis (ALS)... 
DISEASES | GENE | SMN | MULTIDISCIPLINARY SCIENCES | SR PROTEINS | ALS | FUS/TLS | AMYOTROPHIC-LATERAL-SCLEROSIS | MUTATIONS | DIFFERENTIATION | EXON CIRCULARIZATION | Index Medicus
Journal Article
Nature Communications, ISSN 2041-1723, 06/2016, Volume 7, Issue 1, pp. 11706 - 11706
Alternative splicing and alternative polyadenylation (APA) of pre-mRNAs greatly contribute to transcriptome diversity, coding capacity of a genome and gene... 
SEQ DATA | ARABIDOPSIS-THALIANA | SEQUENCES | ALTERNATIVE SPLICING LANDSCAPE | ANTISENSE TRANSCRIPTS | MULTIDISCIPLINARY SCIENCES | GENOME-WIDE ANALYSIS | POLYADENYLATION | PRE-MESSENGER-RNAS | PLANT SR PROTEINS | REVEALS | Index Medicus | 60 APPLIED LIFE SCIENCES
Journal Article
Genes, ISSN 2073-4425, 11/2014, Volume 5, Issue 4, pp. 1050 - 1063
Long non-coding (lnc) RNAs serve a multitude of functions in cells. NEAT1 RNA is a highly abundant 4 kb lncRNA in nuclei, and coincides with paraspeckles,... 
3T3-L1 cells | SR proteins | lncRNA | NEAT1 | Adipogenesis | adipogenesis
Journal Article
NUCLEIC ACIDS RESEARCH, ISSN 0305-1048, 06/2019, Volume 47, Issue 11, pp. 5922 - 5935
Aberrant splicing in exon 11 of the LMNA gene causes the premature aging disorder Hutchinson-Gilford Progeria Syndrome. A de novo C1824T mutation activates an... 
SHAPE | ASF | BIOCHEMISTRY & MOLECULAR BIOLOGY | SR PROTEINS | SITES | PROGERIA | SELECTION | RNA and RNA-protein complexes
Journal Article
JOURNAL OF PATHOLOGY, ISSN 0022-3417, 03/2013, Volume 229, Issue 4, pp. 630 - 639
An increasing body of evidence connects alterations in the process of alternative splicing with cancer development and progression. However, a direct role of... 
APOPTOSIS | KINASE MNK2 | TRANSCRIPTION | PROLIFERATION | SF2/ASF | PATHOLOGY | FAMILY | lung | BREAST-CANCER | amplification | ONCOLOGY | SR PROTEINS | GROWTH | colon | cancer | splicing | SRSF6 | EXPRESSION | oncoprotein
Journal Article
Genome Biology, ISSN 1474-760X, 12/2019, Volume 20, Issue 1, pp. 151 - 151
BACKGROUNDIn multicellular organisms, alternative splicing is central to tissue differentiation and identity. Unicellular protists lack multicellular tissue... 
Index Medicus | Plasmodium | Alternative splicing | SR proteins | Plasmodium berghei | Malaria | Splicing
Journal Article
CELL REPORTS, ISSN 2211-1247, 01/2017, Volume 18, Issue 2, pp. 545 - 556
Most ribosomal proteins (RP) are regarded as essential, static components that contribute only to ribosome biogenesis and protein synthesis. However, emerging... 
SMAD2 | ZEBRAFISH | SR PROTEINS | GENE-EXPRESSION | HNRNP A1 | INDUCTION | ANTAGONISTIC FUNCTIONS | ASSOCIATION | VERTEBRATE GASTRULATION | EMBRYOS | CELL BIOLOGY
Journal Article