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Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2015, Volume 112, Issue 26, pp. 7877 - 7882
Journal Article
Biochemical Journal, ISSN 0264-6021, 12/2005, Volume 392, Issue 2, pp. 249 - 261
The MAPK (mitogen-activated protein kinase) pathway is one of the most important and intensively studied signalling pathways. It is at the heart of a... 
Receptor tyrosine kinase | Signalling network | Systems biology | Extracellular-signal-regulated kinase (ERK) | Computational modelling | Mitogen-activated protein kinase (MAPK) | systems biology | EARLY GENE-PRODUCTS | PROTEIN-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | mitogen-activated protein kinase (MAPK) | BIOCHEMICAL NETWORKS | QUANTITATIVE-ANALYSIS | ERK ACTIVATION | extracellular-signal-regulated kinase (ERK) | GROWTH-FACTOR RECEPTOR | COMPLEX-FORMATION | signalling network | DUAL PHOSPHORYLATION | computational modelling | receptor tyrosine kinase | SIGNAL-REGULATED KINASE | Mitogen-Activated Protein Kinase Kinases - metabolism | Animals | Receptor Protein-Tyrosine Kinases - metabolism | Models, Biological | Computer Simulation | MAP Kinase Signaling System | MEK, MAPK | ODE, ordinary differential equation | MAPKK | MP1, MEK partner 1 | NGF, nerve growth factor | MKP, MAPK phosphatase | Review | MCA, Metabolic Control Analysis | ERK kinase | ERK, extracellular-signal-regulated kinase | PKA, cAMP-activated protein kinase | Shc, Src homology and collagen homology | STAT5, signal transduction and activator of transcription 5 | RSK, ribosomal S6 kinase | FBA, Flux Balance Analysis | SOS, son of sevenless | CD domain, common docking domain | MKKK, MAPKK kinase | PLCγ, phospholipase Cγ | EGF(R), epidermal growth factor (receptor) | FGF, fibroblast growth factor | MKK, MAPK kinase | SBML, Systems Biology Markup Language | JIP, JNK (c-Jun N-terminal kinase)-interacting protein | PDE4, phosphodiesterase 4 | KSR, kinase suppressor of Ras | MAPKKK | Grb2, growth-factor-receptor-bound protein 2 | RTK, receptor tyrosine kinase | GAP, GTPase-activating protein | PDGF, platelet-derived growth factor | MAPK, mitogen-activated protein kinase
Journal Article
2006, Cancer drug discovery and development, ISBN 158829384X, xiii, 290
Leading researchers, from the Novartis group that pioneered Gleevec/Glivec™ and around the world, comprehensively survey the state of the art in the drug... 
Chemotherapy | Inhibitors | Protein-tyrosine kinase | Therapeutic use | Cancer | Biology, life sciences
Book
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2010, Volume 107, Issue 36, pp. 15757 - 15762
Journal Article