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Nature Reviews Drug Discovery, ISSN 1474-1776, 12/2018, Volume 18, Issue 1, pp. 41 - 58
Given the high attrition rates, substantial costs and slow pace of new drug discovery and development, repurposing of 'old' drugs to treat both common and rare... 
3 RECEPTOR ANTAGONISM | SARACATINIB AZD0530 | SMALL MOLECULES | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENE-EXPRESSION | PHASE-II | PHARMACOLOGY & PHARMACY | SRC KINASE | AMYOTROPHIC-LATERAL-SCLEROSIS | KINASE INHIBITOR | WIDE ASSOCIATION | DISEASE RELATIONSHIPS | Drug discovery | Planning | Pharmaceutical industry | Methods
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 02/2010, Volume 30, Issue 2, pp. 200 - 206
OBJECTIVE—To investigate the capacity of the adipokine leptin to promote angiogenesis by modulating the function of circulating angiogenic cells (CACs).... 
Angiogenesis | Obesity | Src kinase | Circulating angiogenic cells | PTP1B | Leptin | circulating angiogenic cells | leptin | angiogenesis | obesity
Journal Article
Chemical Reviews, ISSN 0009-2665, 12/2016, Volume 116, Issue 23, pp. 14726 - 14768
The ruthenium-catalyzed azide alkyne cycloaddition (RuAAC) affords 1,5-disubstituted 1,2,3-triazoles in one step and complements the more established... 
SITU CLICK-CHEMISTRY | DIVERSITY-ORIENTED SYNTHESIS | ONE-POT SYNTHESIS | SOLID-PHASE SYNTHESIS | 1,3-DIPOLAR CYCLOADDITION | METAL-METAL BONDS | PROTEIN-PROTEIN INTERACTIONS | 1,5-DISUBSTITUTED 1,2,3-TRIAZOLES | ORGANIC AZIDES | CHEMISTRY, MULTIDISCIPLINARY | C-SRC KINASE | Organisk kemi | Kemi | Chemical Sciences | Organic Chemistry
Journal Article
The Journal of Physiology, ISSN 0022-3751, 03/2019, Volume 597, Issue 6, pp. 1429 - 1430
Journal Article
Journal of Cerebral Blood Flow and Metabolism, ISSN 0271-678X, 2019, p. 271678X18822801
Exposure of the brain to high levels of glucocorticoids during ischemia-reperfusion induces neuronal cell death. Oxidative stress alters blood-brain barrier... 
P-glycoprotein | Abl kinase | Src kinase | oxidative stress | Blood–brain barrier
Journal Article
Organic Process Research & Development, ISSN 1083-6160, 10/2015, Volume 19, Issue 10, pp. 1400 - 1410
The use of the “borrowing hydrogen strategy” in the synthesis of a number of typical pharmaceutical intermediates has been investigated. The main aim of this... 
ALCOHOLS | ETHYLENE-GLYCOL | NITROGEN-HETEROCYCLES | SRC KINASE INHIBITOR | EFFICIENT SYNTHESIS | CHEMISTRY, ORGANIC | PRIMARY AMINES | RUTHENIUM-COMPLEX | CHEMISTRY, APPLIED | IRIDIUM COMPLEX | SELECTIVE ALKYLATION | CATALYZED N-ALKYLATION
Journal Article
Toxicology in Vitro, ISSN 0887-2333, 02/2019, Volume 62, p. 104677
Doxorubicin (DOX) has dose-dependent toxicity on ovarian follicles (OFs), and the inhibition of different signaling molecules along with the DOX application... 
Src kinase | PIM kinases | Ca2+ signaling | Doxorubicin | Ovarian follicles | Microfluidics
Journal Article
Nitric Oxide, ISSN 1089-8603, 12/2019, Volume 93, pp. 78 - 89
Human immunodeficiency virus (HIV) infections are typically accompanied by high levels of secreted inflammatory cytokines and generation of high levels of... 
Oxidative stress | Cellular redox status | Src kinase | HIV | Viral load | Nitric oxide
Journal Article
Cancer research, ISSN 0008-5472, 12/2012, Volume 72, Issue 24, pp. 6435 - 6446
MicroRNAs (miRNAs) have great potential as biomarkers and therapeutic agents owing to their ability to control multiple genes and potential to influence... 
MicroRNA-23b | Src kinase | prostate cancer
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 12/2005, Volume 25, Issue 12, pp. 2673 - 2678
OBJECTIVE—Both collagen and tissue factor can be initiating factors in thrombus formation. We investigated the signaling pathway of collagen-induced platelet... 
Glycoprotein VI | Src kinase | Thrombin | Platelets | LAT
Journal Article