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acss2, acyl-coenzyme a synthetase short-chain family member 2 (2) 2
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adh 1 and 2, alcohol dehydrogenase 1 and 2 (2) 2
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Journal of Hepatology, ISSN 0168-8278, 2015, Volume 62, Issue 6, pp. 1398 - 1404
Graphical abstract 
Gastroenterology and Hepatology | 3-hydroxy-3-methylglutaryl-CoA reductase | Stearoyl-CoA desaturase | Non-alcoholic fatty liver disease | Lipogenesis | FGF19 | 3-hydroxy-3-methylglutaryl- CoA reductase | Ursodeoxycholic Acid - administration & dosage | Oleic Acid - metabolism | Bile Acids and Salts - biosynthesis | Humans | Liver - metabolism | Bile Acids and Salts - metabolism | Non-alcoholic Fatty Liver Disease - metabolism | Intra-Abdominal Fat - metabolism | Obesity, Morbid - drug therapy | Non-alcoholic Fatty Liver Disease - drug therapy | Ursodeoxycholic Acid - pharmacology | Stearoyl-CoA Desaturase - biosynthesis | Liver - drug effects | Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors | Lipid Metabolism - drug effects | Intra-Abdominal Fat - drug effects | Obesity, Morbid - metabolism | Physiological aspects | Obesity | Ursodiol | Deoxycholic acid | Index Medicus | BAs, bile acids | nCEH, neutral cholesterol ester hydrolase | ApoB, apolipoprotein B | LDLR, low density lipoprotein receptor | FGF19, fibroblast growth factor 19 | VLDL, very low density lipoproteins | ABC, ATP-binding cassette | TGs, triglycerides | NAFLD, non-alcoholic fatty liver disease | OA, oleic acid | C4, 7α-hydroxy-4-cholesten-3-one | SHP, small heterodimer partner | SREBP1c, sterol regulatory element-binding protein-1c | CA, cholic acid | PA, palmitic acid | FATP1, fatty acid transport protein 1 | UDCA, ursodeoxycholic acid | FAs, fatty acides | HMGCR, 3-hydroxy-3-methylglutaryl-CoA reductase | vWAT, visceral white adipose tissue | SCD, stearoyl-Coa desaturase | CYP7A1, cholesterol 7α-hydroxylase | NASH, non-alcoholic steatohepatitis | FXR, farnesoid X receptor | CDCA, chenodeoxycholic acid | MA, myristic acid | FASN, fatty acid synthase | MTTP, microsomal triglyceride transfer protein | SA, stearic acid | NONALCOHOLIC | FATTY LIVER-DISEASE | NUCLEAR RECEPTOR | CHOLESTEROL-METABOLISM | Gastroenterology & Hepatology | TRANSPORT | Endokrinologi och diabetes | FEEDBACK-REGULATION | STEATOHEPATITIS | PLACEBO-CONTROLLED TRIAL | COA DESATURASE | EXPRESSION | Endocrinology and Diabetes | ADIPOSE-TISSUE
Journal Article
BBA - Molecular and Cell Biology of Lipids, ISSN 1388-1981, 07/2016, Volume 1861, Issue 7, pp. 584 - 593
We have previously shown that high fat (HF) feeding during pregnancy primes the development of non-alcoholic steatohepatits (NASH) in the adult offspring.... 
Development | Aging | Fatty liver | High fat | Circadian | Maternal diet | DE-NOVO | REV-ERB | NUCLEAR RECEPTORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | LIPOTOXICITY | NONALCOHOLIC FATTY LIVER | DEACETYLASE SIRT3 | BIOPHYSICS | CIRCADIAN-CLOCK | METABOLISM | DISEASE | MICE | Sirtuin 1 - metabolism | Liver - pathology | Sirtuin 3 - metabolism | Diet, High-Fat - adverse effects | Non-alcoholic Fatty Liver Disease - etiology | CLOCK Proteins - genetics | Sirtuin 1 - genetics | Nuclear Receptor Subfamily 1, Group F, Member 1 - metabolism | CLOCK Proteins - metabolism | Female | Lipid Metabolism - genetics | Nuclear Receptor Subfamily 1, Group D, Member 1 - metabolism | Repressor Proteins - metabolism | Sterol Regulatory Element Binding Protein 1 - metabolism | Disease Models, Animal | Sirtuin 3 - genetics | Nuclear Receptor Subfamily 1, Group D, Member 1 - genetics | Non-alcoholic Fatty Liver Disease - genetics | Oxidation-Reduction | Signal Transduction | Liver - metabolism | Mice, Inbred C57BL | Circadian Rhythm - genetics | Gene Expression Regulation | Repressor Proteins - genetics | Non-alcoholic Fatty Liver Disease - metabolism | Photoperiod | Receptors, Cytoplasmic and Nuclear - genetics | Non-alcoholic Fatty Liver Disease - physiopathology | Prenatal Exposure Delayed Effects - physiopathology | Prenatal Exposure Delayed Effects - metabolism | Pregnancy | Prenatal Exposure Delayed Effects - genetics | Animals | Sterol Regulatory Element Binding Protein 1 - genetics | Mice | Nuclear Receptor Subfamily 1, Group F, Member 1 - genetics | Receptors, Cytoplasmic and Nuclear - metabolism | Gene expression | Physiological aspects | Genetic transcription | DNA binding proteins | Genes | Liver
Journal Article
Molecular Metabolism, ISSN 2212-8778, 11/2017, Volume 6, Issue 11, pp. 1395 - 1406
Excess ethanol consumption has serious pathologic consequences. In humans, repeated episodes of binge drinking can lead to liver damage and have adverse... 
Binge ethanol consumption | Chronic ethanol consumption | FGF21 | Alcoholic liver disease | SIGNAL | PPAR-ALPHA | ACTIVATION | LIPID-METABOLISM | PROTEIN RESTRICTION | FIBROBLAST-GROWTH-FACTOR-21 | HUMANS | ALCOHOL PREFERENCE | DISEASE | ENDOCRINOLOGY & METABOLISM | FATTY LIVER
Journal Article
Acta Pharmaceutica Sinica B, ISSN 2211-3835, 2015, Volume 5, Issue 2, pp. 129 - 134
The classical functions of bile acids include acting as detergents to facilitate the digestion and absorption of nutrients in the gut. In addition, bile acids... 
Transporters | Energy homeostasis | Bile acids | Lipid metabolism | Intestine | Liver | FIBROBLAST GROWTH FACTOR-19 | TRIGLYCERIDE LEVELS | NUCLEAR RECEPTOR | GLUCOSE-HOMEOSTASIS | INSULIN-RESISTANCE | ALPHA-OST-BETA | GENE-EXPRESSION | FARNESOID-X-RECEPTOR | PHARMACOLOGY & PHARMACY | WEIGHT-GAIN | MICE | IBABP, ileal bile acid binding protein | PPAR, peroxisome proliferator-activated receptor | GLP-1, glucagon-like polypeptide-1 | Review | PEPCK, phosphoenolpyruvate carboxykinase | FXR, farnesoid X-receptor | T4, thyroid hormone | BSEP, bile salt export pump | G6Pase, glucose-6-phosphatase | SHP, small heterodimer partner | FGFR4, fibroblast growth factor receptor 4 | OST, organic solute transporter | LDL, low density lipoprotein | CYP7A1, cholesterol 7α-hydroxylase | DIO2, deiodinase 2 | FGF, fibroblast growth factor | APO, apolipoproteins | PGC1α, peroxisome proliferator-activated receptor gamma coactivator 1 alpha | SREBP1c, sterol regulatory element binding protein-1c | OATP, organic anion transporting polypeptide | TGR5, G-protein-coupled bile acid receptor | ASBT, apical sodium-dependent bile acid transporter | FAS, fatty acid synthase | NTCP, Na+-taurocholate transporting polypeptide | FOXO1, forkhead box protein O1 | VLDL, very low density lipoprotein | ACCII, acetyl-CoA carboxylase 2 | HNF4α, hepatocyte nuclear factor 4 alpha
Journal Article
Journal Article
Nutrition Research, ISSN 0271-5317, 2008, Volume 28, Issue 6, pp. 414 - 422
Abstract The aim of present study was to identify the visceral adipose tissue genes differentially expressed in a well-characterized rat model of high-fat diet... 
Gastroenterology and Hepatology | NADPH | EFA | tumor necrosis factor α | high-density lipoprotein | HFD | Lnk | cDNA microarray | glucose transporter 4 | HDL | Sprague-Dawley | CIP4 | sterol-regulatory-element-binding protein-1c | SREBP1c | Stx6 | HSP10 | TNF α | Rac1 | syntaxin 6c | polymerase chain reaction | PPAR γ2 | CCAAT/enhancer-binding protein α | PBS | protein phosphatase 2 (formerly 2A) | resistin, peroxisome proliferator activated receptor γ2 | nicotinamide adenine dinucleotide phosphate | Rats | phosphate buffer saline | PP2A | Gene expression | essential fatty acids | ras-related C3 botulinum toxin substrate 1 | Epididymal adipose tissue | High-fat diet | heat shock 10-kd protein 1 | linker of T-cell receptor pathways 10 | C/EBP α | Insulin resistance | cell division interacting protein 4 | GLUT4 | normal diet | PCR | C/EBPα | TNFα | PPARγ2 | 3T3-L1 ADIPOCYTES | TRANSLOCATION | HEPATOCYTES | PROTEIN | epididymal adipose tissue | TRAFFICKING | ADIPOGENESIS | INSULIN | NUTRITION & DIETETICS | METABOLISM | high-fat diet | LEPTIN DEFICIENCY | rats | insulin resistance | gene expression | ADIPOSE-TISSUE | Epididymis - metabolism | Body Weight | Insulin - analysis | Liver - enzymology | Leptin - analysis | Oligonucleotide Array Sequence Analysis - methods | C-Peptide - analysis | Male | Gene Expression Profiling | Intra-Abdominal Fat - metabolism | Obesity - genetics | Liver - chemistry | Obesity - metabolism | Gene Expression Regulation - drug effects | Animals | Insulin Resistance - physiology | Dietary Fats - administration & dosage | Rats, Sprague-Dawley - genetics | Lipids - analysis | Glucose - analysis | Obesity | DNA microarrays | Leptin | Genes | Genetic research | Glucose | T cells | Dextrose | Protein binding
Journal Article
Biochemistry and Biophysics Reports, ISSN 2405-5808, 09/2016, Volume 7, pp. 84 - 90
Beef fat is a natural source of fatty acids, and is typically enriched with either 10-18:1 or 11-18:1. Little is known about the bioactivity of individual... 
Cell culture | Cytotoxicity | Beef | Fatty acid metabolism | Liver | Trans fatty acids
Journal Article
BBA - Molecular and Cell Biology of Lipids, ISSN 1388-1981, 2010, Volume 1801, Issue 4, pp. 421 - 429
Cold adaptation elicits a paradoxical simultaneous induction of fatty acid synthesis and β-oxidation in brown adipose tissue. We show here that cold exposure... 
Brown adipocytes | PGC1α | ADD1/SREBP1c | LXR | Adipogenesis | HEPATIC GLUCONEOGENESIS | FATTY-ACID SYNTHESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ELEMENT-BINDING PROTEIN-1C | LXR-ALPHA | CELL BIOLOGY | PGC1 alpha | WHITE FAT | BIOPHYSICS | ADAPTIVE THERMOGENESIS | COACTIVATOR PGC-1 | GENE-EXPRESSION | LIVER-X-RECEPTORS | ADIPOSE-TISSUE
Journal Article
Liver International, ISSN 1478-3223, 05/2012, Volume 32, Issue 5, pp. 761 - 770
Background Previous studies demonstrated that the Long‐Evans (LE) rats exhibited liver injury and lipid metabolic abnormalities after 8 weeks of ethanol... 
SREBP1c | alcoholic liver disease | Lieber–DeCarli diet | p53 | Lieber-DeCarli diet | Alcoholic liver disease | P53 | APOPTOSIS | CELLS | ACTIVATION | INVOLVEMENT | ALCOHOLIC FATTY LIVER | PROLIFERATION | PATHWAY | TARGETS | PROTEINS | GASTROENTEROLOGY & HEPATOLOGY | EXPRESSION | Up-Regulation | Cell Fractionation | Ethanol - toxicity | Gene Expression - drug effects | Fatty Liver - pathology | Rats, Long-Evans | Ethanol - administration & dosage | Male | Alanine Transaminase - blood | Gene Expression Profiling | Fatty Liver - chemically induced | Liver Cirrhosis - chemically induced | Triglycerides - analysis | Liver - drug effects | Early Growth Response Protein 1 - genetics | Central Nervous System Depressants - toxicity | Liver Cirrhosis - genetics | Sterol Regulatory Element Binding Protein 1 - metabolism | Disease Models, Animal | Biomarkers - metabolism | Fatty Liver - genetics | Liver - metabolism | Rats | Liver - chemistry | Animals | Early Growth Response Protein 1 - biosynthesis | Sterol Regulatory Element Binding Protein 1 - genetics | Central Nervous System Depressants - administration & dosage | Liver Cirrhosis - pathology | Protein Binding | Animal Feed | Enzymes | Chromatin | Transcription factors | Immunoprecipitation | EGR-1 protein | Ethanol | Liver | Triglycerides | Gene expression | Fatty acids | Promoters | p53 protein | Feeding | Diets | Fatty liver | Sterols | DNA | Fibrosis | Alanine transaminase | Lipid metabolism | steatosis | Injuries
Journal Article
Biochemical Journal, ISSN 0264-6021, 01/2010, Volume 425, Issue 1, pp. 215 - 223
The transcription factor SREBP1c (sterol-regulatory-element-binding protein 1c) is highly expressed in adipose tissue and plays a central role in several... 
Adipocyte | CCAAT/enhancer-binding protein(C/EBP) | Sterol-regulatory-element-binding protein 1c(SREBP1c) | Transcription | Lipid | Adipogenesis | transcription | BIOCHEMISTRY & MOLECULAR BIOLOGY | ELEMENT-BINDING PROTEIN-1C | ALPHA | sterol-regulatory-element-binding protein 1c (SREBP1c) | lipid | BETA | adipogenesis | INSULIN-RESISTANCE | adipocyte | LIPODYSTROPHY | ADIPOCYTE DIFFERENTIATION | PPAR-GAMMA | ADD1/SREBP1 | CCAAT/enhancer-binding protein (C/EBP) | MICE | ADIPOSE-TISSUE | CCAAT-Enhancer-Binding Protein-alpha - metabolism | Humans | Adipocytes - cytology | DNA-Binding Proteins - metabolism | Chromatin Immunoprecipitation | RNA Interference | CCAAT-Enhancer-Binding Protein-delta - metabolism | CCAAT-Enhancer-Binding Proteins - genetics | Sterol Regulatory Element Binding Protein 1 - metabolism | CCAAT-Enhancer-Binding Proteins - metabolism | Proto-Oncogene Proteins - metabolism | Promoter Regions, Genetic | CCAAT-Enhancer-Binding Protein-beta - genetics | Cells, Cultured | Gene Expression Regulation | Proto-Oncogene Proteins - genetics | Transcription Factors - genetics | 3T3-L1 Cells | DNA-Binding Proteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | CCAAT-Enhancer-Binding Protein-beta - metabolism | RUNX1 Translocation Partner 1 Protein | Transcription Factors - metabolism | Animals | Sterol Regulatory Element Binding Protein 1 - genetics | CCAAT-Enhancer-Binding Protein-delta - genetics | Adipocytes - metabolism | CCAAT-Enhancer-Binding Protein-alpha - genetics | Protein Binding | Mice
Journal Article
Molecular Biology Reports, ISSN 0301-4851, 3/2011, Volume 38, Issue 3, pp. 2037 - 2042
Journal Article