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phosphorylation (12) 12
biochemistry & molecular biology (11) 11
humans (11) 11
protein-serine-threonine kinases - metabolism (10) 10
srpk (10) 10
animals (9) 9
protein-serine-threonine kinases - genetics (8) 8
amino acid sequence (6) 6
localization (6) 6
alternative splicing (5) 5
protein-serine-threonine kinases - chemistry (5) 5
rna splicing factors (5) 5
sr protein (5) 5
cell biology (4) 4
identification (4) 4
molecular sequence data (4) 4
nuclear proteins - metabolism (4) 4
proteins (4) 4
serine-rich (4) 4
apoptosis (3) 3
cell line, tumor (3) 3
conserved sequence (3) 3
kinases (3) 3
mutation - genetics (3) 3
protein kinase (3) 3
protein kinases (3) 3
research article (3) 3
rna-binding proteins - metabolism (3) 3
saccharomyces-cerevisiae (3) 3
serine (3) 3
angiogenesis (2) 2
base sequence (2) 2
biophysics (2) 2
cell cycle (2) 2
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clk (2) 2
cloning, molecular (2) 2
domain (2) 2
drosophila (2) 2
drosophila proteins - genetics (2) 2
drosophila proteins - metabolism (2) 2
enzyme activation (2) 2
erk, extracellular-signal-regulated kinase (2) 2
female (2) 2
fission yeast (2) 2
gfp, green fluorescent protein (2) 2
hela cells (2) 2
in-vivo (2) 2
kinase (2) 2
kinase-substrate interaction (2) 2
lamin-b receptor (2) 2
leukemia (2) 2
mammalian-cells (2) 2
messenger rna (2) 2
mice (2) 2
models, molecular (2) 2
nuclear import (2) 2
nuclear proteins - genetics (2) 2
pre-messenger-rna (2) 2
processive phosphorylation (2) 2
protein kinase inhibitors - pharmacology (2) 2
protein phosphorylation (2) 2
protein structure, tertiary (2) 2
protein-kinases (2) 2
recombinant fusion proteins - genetics (2) 2
recombinant fusion proteins - metabolism (2) 2
rna (2) 2
rna-binding proteins - genetics (2) 2
sequence alignment (2) 2
serine-arginine splicing factors (2) 2
serine/arginine-rich protein (2) 2
signal transduction (2) 2
splicing (2) 2
sr proteins (2) 2
srpin340 (2) 2
substrate specificities (2) 2
substrate specificity (2) 2
transcription, genetic (2) 2
1-phosphatidylinositol 3-kinase (1) 1
a-beta (1) 1
acetylation (1) 1
active zone (1) 1
acute lymphatic leukemia (1) 1
acute myeloid leukemia (1) 1
aicar, aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (1) 1
akt inhibitor (1) 1
akt protein (1) 1
alternative splicing - drug effects (1) 1
alternative splicing - genetics (1) 1
alzheimers-disease (1) 1
amino acids (1) 1
ampk, amp-activated protein kinase (1) 1
amplification (1) 1
amyloid precursor protein (1) 1
analysis (1) 1
anti-cancer drugs (1) 1
antibodies, monoclonal (1) 1
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Biochemical journal, ISSN 1470-8728, 2007, Volume 408, Issue 3, pp. 297 - 315
The specificities of 65 compounds reported to be relatively specific inhibitors of protein kinases have been profiled against a panel of 70-80 protein kinases... 
Drug discovery | Kinase profiling | Protein kinase | Anti-cancer drugs | Inhibitor specificity | RHO-ASSOCIATED KINASE | TUMOR PROGRESSION | FAMILY-MEMBERS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL-PROLIFERATION | protein kinase | P38 MAP KINASE | CYCLIN-DEPENDENT KINASES | RECEPTOR TYROSINE KINASES | drug discovery | kinase profiling | SB 203580 | anti-cancer drugs | ISOFORMS IN-VITRO | P90 RSK | inhibitor specificity | Amino Acid Sequence | Cell Line | Phosphorylation | Recombinant Proteins - antagonists & inhibitors | Animals | Mitogen-Activated Protein Kinases - antagonists & inhibitors | Humans | Drug Design | Protein Kinase Inhibitors - pharmacology | Enzyme Activation | Mitogen-Activated Protein Kinases - metabolism | Spodoptera | Yes1, Yamaguchi sarcoma viral oncogene homologue 1 | CSK, C-terminal Src kinase | Lck, lymphocyte cell-specific protein-tyrosine kinase | EGF, epidermal growth factor | FGF-R, fibroblast-growth-factor receptor | PAK, p21-activated protein kinase | PDK, 3-phosphoinositide-dependent protein kinase | PI3K, phosphatidylinositol (phosphoinositide) 3-kinase | NEK, NIMA (never in mitosis in Aspergillus nidulans)-related kinase | RSK, p90 ribosomal S6 kinase | HEK-293 cells, human embryonic kidney-293 cells | VEGF, vascular endothelial growth factor (vasoendothelial growth factor) | EF2K, elongation-factor-2 kinase | CK, casein kinase | PTEN, phosphatase and tensin homologue deleted on chromosome 10 | ERK, extracellular-signal-regulated kinase | ATM, ataxia telangiectasia mutated | SRPK, serine-arginine protein kinase | IL-1, interleukin 1 | MNK, MAPK-integrating protein kinase | ROCK, Rho-dependent protein kinase | CaMKK, CaMK kinase | GST, glutathione transferase | MKK1, MAPK kinase-1 (also called MEK1, MAPK or ERK kinase 1) | GAK, cyclin G-associated kinase | FMK, fluoromethylketone | MST, mammalian homologue Ste20-like kinase | PKA, cAMP-dependent protein kinase | FKBP, FK506-binding protein | PPAR, peroxisome-proliferator-activated receptor | IKK, inhibitory κB kinase | PH, pleckstrin homology | MBP, myelin basic protein | AICAR, aminoimidazole-4-carboxamide-1-β-D-ribofuranoside | MAPKAP-K, MAPK-activated protein kinase | Sf21, Spodoptera frugiperda (fall armyworm) 21 | MARK, microtubule-affinity-regulating kinase | PIM, provirus integration site for Moloney murine leukaemia virus | LPS, lipopolysaccharide | MSK, mitogen- and stress-activated protein kinase | MAPK, mitogen-activated protein kinase | MELK, maternal embryonic leucine-zipper kinase | His6, hexahistidine | CAK, cyclin-dependent kinase-activating kinase | Eph-A2, Ephrin A2 receptor | PLK, polo-like kinase | ATF2, activating transcription factor 2 | PKD, protein kinase D | Src, sarcoma kinase | AMPK, AMP-activated protein kinase | MMS, methyl methanesulfonate | CHK, checkpoint kinase | JNK, c-Jun N-terminal kinase | TORC1, mTOR (mammalian target of rapamycin)–raptor (regulatory associated protein of mTOR) complex | BRSK, brain-specific kinase | RIP2, receptor-interacting protein 2 | IGF-1, insulin-like growth factor-1 | S6K1, S6 kinase 1 | DYRK, dual-specificity tyrosine-phosphorylated and -regulated kinase | HIPK, homeodomain-interacting protein kinase | ZMP, aminoimidazole-4-carboxamide-1-β-D-ribofuranoside monophosphate | PRAK, p38-regulated activated kinase | PKC, protein kinase C | Src-I1, Src inhibitor 1 | TANK, TRAF (tumour-necrosis-factor-receptor-associated factor)-family-member-associated nuclear factor κB activator | NFAT, nuclear factor for activated T-cells | PHK, phosphorylase kinase | GSK3, glycogen synthase kinase 3 | PKB, protein kinase B (also called Akt) | CaMK, calmodulin-dependent kinase | CDK, cyclin-dependent protein kinase | NDRG, N-myc downstream-regulated gene | SmMLCK, smooth-muscle myosin light-chain kinase | TBK1, TANK-binding kinase 1 | PRK, protein kinase C-related kinase | SGK, serum- and glucocorticoid-induced kinase
Journal Article
Cells (Basel, Switzerland), ISSN 2073-4409, 2019, Volume 8, Issue 11, p. 1333
.... The self-assembly and synaptic recruitment of the Drosophila protein Bruchpilot (BRP), a partial homolog of CAST1/ERC2, is modulated by the serine-arginine protein kinase (SRPK79D... 
CAST | CYTOMATRIX | CORE | CAST1/ERC2 | PHOSPHORYLATION | active zone | BRUCHPILOT | synapse | PICCOLO | ZINC | CELL BIOLOGY | BASSOON | GEPHYRIN | coiled-coil | SRPK | RIM1 | self-aggregation | cast1/erc2 | srpk
Journal Article
Journal Article
European journal of medicinal chemistry, ISSN 0223-5234, 07/2017, Volume 134, pp. 97 - 109
Journal Article
Genes & development, ISSN 0890-9369, 09/2005, Volume 19, Issue 17, pp. 2066 - 2077
... a novel MEF2-regulated gene encoding a muscle-specific protein kinase, Srpk3, belonging to the serine arginine protein kinase (SRPK... 
Serine arginine protein kinase (SRPK) | Centronuclear myopathy | Transcriptional regulation | Stk23/Srpk3 | Myocyte enhancer factor 2 | INTERMEDIATE-LAYER PROTEIN | DEVELOPMENT IN-VIVO | MOUSE EMBRYOGENESIS | transcriptional regulation | NUCLEAR EXPORT | DEVELOPMENTAL BIOLOGY | ENHANCER FACTOR-2 MEF2 | CELL BIOLOGY | centronuclear myopathy | LOOP-HELIX PROTEINS | SKELETAL-MUSCLE | myocyte enhancer factor 2 | LAMIN-B RECEPTOR | GENETICS & HEREDITY | GENE-EXPRESSION | serine arginine protein kinase (SRPK) | RNA SPLICING FACTORS | Protein-Serine-Threonine Kinases - deficiency | Transcription Factors - deficiency | Molecular Sequence Data | Myopathies, Structural, Congenital - genetics | Gene Expression Profiling | DNA-Binding Proteins - deficiency | DNA-Binding Proteins - metabolism | Gene Expression Regulation, Developmental | Base Sequence | Transcription, Genetic | Muscle, Skeletal - embryology | MEF2 Transcription Factors | Protein-Serine-Threonine Kinases - metabolism | Amino Acid Sequence | Muscle, Skeletal - enzymology | Signal Transduction | Mice, Inbred C57BL | Myopathies, Structural, Congenital - enzymology | Protein-Serine-Threonine Kinases - genetics | Mice, Transgenic | Myogenic Regulatory Factors | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Mice, Knockout | DNA - genetics | Gene Expression Regulation, Enzymologic | Transcription Factors - metabolism | Animals | Enhancer Elements, Genetic | Myopathies, Structural, Congenital - pathology | Mice | Muscle, Skeletal - pathology | Myopathies, Structural, Congenital - etiology | DNA microarrays | Analysis | Rattus | Homeostasis | Rats | Physiological aspects | Genetic aspects | Diagnosis | Central core myopathy | Research Papers | Stk23 | Srpk3
Journal Article
The EMBO journal, ISSN 0261-4189, 2011, Volume 30, Issue 3, pp. 510 - 523
Journal Article
Biochemical journal, ISSN 1470-8728, 2007, Volume 405, Issue 1, pp. 21 - 30
Evolutionarily conserved SR proteins (serine/arginine-rich proteins) are important factors for alternative splicing and their activity is modulated by SRPKs... 
Green fluorescent protein (GFP)-fusion protein | Alternative splicing | Serine/arginine-rich protein (SR protein) | Cellular localization | Protein phosphorylation | Protein kinase | NUCLEAR IMPORT | LAMMER KINASE | CELLS | alternative splicing | BIOCHEMISTRY & MOLECULAR BIOLOGY | HOMOLOG | protein phosphorylation | serine/arginine-rich protein (SR protein) | SACCHAROMYCES-CEREVISIAE | green fluorescent protein (GFP)-fusion protein | protein kinase | MODULAR DOMAINS | cellular localization | NEGATIVE REGULATION | IN-VIVO | RICH SPLICING FACTORS | SCHIZOSACCHAROMYCES-POMBE | RNA-Binding Proteins - genetics | Phosphorylation | Schizosaccharomyces pombe Proteins - genetics | Alternative Splicing | Humans | Protein-Serine-Threonine Kinases - genetics | RNA Splicing Factors | Schizosaccharomyces - physiology | Recombinant Fusion Proteins - metabolism | Phenotype | Animals | Cell Nucleus - metabolism | Schizosaccharomyces pombe Proteins - metabolism | Recombinant Fusion Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | RNA-Binding Proteins - metabolism | serine | Clk | NES, nuclear export signal | mAb, monoclonal antibody | tyrosine kinase | Cdc28p-like kinase or serine | RS domain, arginine | Dsk1p, dis1-suppressing protein kinase | ts mutant, temperature-sensitive mutant | HRP, horseradish peroxidase | RBD, RNA-binding domain | Kic1p, kinase in Clk family | ESE, exonic splicing enhancer | TRN-SR2, transportin-SR2 | nmt+, no message in thiamine | GFP, green fluorescent protein | arginine-rich protein (SR protein) | arginine-rich protein | EMM2, Edinburgh minimal medium 2 | serine-rich domain | wt, wild-type | NLS, nuclear localization signal | NOR, nucleolar organizing region | DAPI, 4′,6-diamidino-2-phenylindole | SRPK, SR protein-specific kinase | threonine | SR protein, serine | Sty, Cdc2p | U2AF, U2 auxiliary factor
Journal Article