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1. Full Text High-sensitivity ST2 for prediction of adverse outcomes in chronic heart failure
by Ky, Bonnie and French, Benjamin and McCloskey, Kristin and Rame, J. Eduardo and McIntosh, Erin and Shahi, Puja and Dries, Daniel L and Tang, W.H. Wilson and Wu, Alan H.B and Fang, James C and Boxer, Rebecca and Sweitzer, Nancy K and Levy, Wayne C and Goldberg, Lee R and Jessup, Mariell and Cappola, Thomas P
Circulation: Heart Failure, ISSN 1941-3289, 03/2011, Volume 4, Issue 2, pp. 180 - 187
Background-Soluble ST2 reflects activity of an interleukin-33-dependent cardioprotective signaling axis and is a diagnostic and prognostic marker in acute... 
ST2 | Cardiomyopathy | Chronic heart failure | MORTALITY | SURVIVAL | CARDIAC & CARDIOVASCULAR SYSTEMS | RECEPTOR | chronic heart failure | NATRIURETIC PEPTIDE | SERUM-SOLUBLE ST2 | BIOMARKERS | FAMILY-MEMBER ST2 | RECLASSIFICATION | PLASMA | ACUTE MYOCARDIAL-INFARCTION | cardiomyopathy | Heart Failure - surgery | Interleukin-1 Receptor-Like 1 Protein | Predictive Value of Tests | Prognosis | Prospective Studies | United States | Humans | Middle Aged | Male | Heart Failure - blood | Time Factors | Peptide Fragments - blood | Adult | Female | Natriuretic Peptide, Brain - blood | Heart Failure - mortality | Risk Assessment | Risk Factors | Kaplan-Meier Estimate | Proportional Hazards Models | Heart Transplantation | Receptors, Cell Surface - blood | Biomarkers - blood | Chi-Square Distribution | Analysis of Variance | ROC Curve | Aged | Chronic Disease | Index Medicus
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2. Full Text Interleukin-33 enhances adhesion, CD11b expression and survival in human eosinophils
by Suzukawa, Maho and Koketsu, Rikiya and Iikura, Motoyasu and Nakae, Susumu and Matsumoto, Kenji and Nagase, Hiroyuki and Saito, Hirohisa and Matsushima, Kouji and Ohta, Ken and Yamamoto, Kazuhiko and Yamaguchi, Masao
Laboratory Investigation, ISSN 0023-6837, 11/2008, Volume 88, Issue 11, pp. 1245 - 1253
Eosinophils are important effector cells in allergic diseases, but the mechanisms regulating their biological functions remain obscure. Interleukin-33 (IL-33)... 
Human | ST2 | IL-1 | IL-33 | IL-18 | Eosinophil | MEDICINE, RESEARCH & EXPERIMENTAL | HUMAN BASOPHILS | TH2 CELLS | MAST-CELLS | CROSS-LINKING | IL-1 RECEPTOR | SOLUBLE ST2 | PATHOLOGY | CYTOKINE PRODUCTION | GENE | eosinophil | human | T1/ST2 | ANTIGEN | Interleukin-1 Receptor-Like 1 Protein | Eosinophils - metabolism | Interleukins - physiology | Cell Adhesion - physiology | Cell Survival | Interleukin-33 | Humans | Cells, Cultured | Receptors, Cell Surface - metabolism | Apoptosis - physiology | CD11b Antigen - metabolism | Index Medicus
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3. Full Text Characteristics of the Novel Interleukin Family Biomarker ST2 in Patients With Acute Heart Failure
by Rehman, Shafiq U., MD and Mueller, Thomas, MD and Januzzi, James L., MD, FACC
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2008, Volume 52, Issue 18, pp. 1458 - 1465
Objectives The purpose of this study was to examine the patient-specific characteristics of the interleukin-1 receptor family member ST2 in patients with acute... 
Cardiovascular | Internal Medicine | ST2 | mortality | heart failure | NT-proBNP | RESPONSE GENE | AMINO-TERMINAL PROBNP | CARDIAC & CARDIOVASCULAR SYSTEMS | BRAIN NATRIURETIC PEPTIDE | MYOCARDIAL-INFARCTION | SOLUBLE ST2 | 1-YEAR MORTALITY | EMERGENCY-DEPARTMENT | SEPTIC SHOCK | MEMBER ST2 | CRITICALLY-ILL PATIENTS | Biomarkers - metabolism | Interleukin-1 Receptor-Like 1 Protein | Severity of Illness Index | Acute Disease | Prognosis | Prospective Studies | Enzyme-Linked Immunosorbent Assay | Signal Transduction | Humans | Proportional Hazards Models | Receptors, Cell Surface - metabolism | Male | Heart Failure - metabolism | Heart Failure - blood | Disease Progression | Receptors, Interleukin-1 - metabolism | Inflammation - metabolism | Time Factors | Female | ROC Curve | Aged | Heart Failure - diagnosis | Heart Failure - mortality | Heart failure | Care and treatment | C-reactive protein | Interleukins | Cardiac patients | Natriuretic peptides | Enzymes | Heart attacks | Peptides | Cytokines | Mortality | Cardiovascular disease | Statistical methods | Regression analysis | Family medical history | Proteins | Confidence intervals | Variables | Body mass index | Software | Blood pressure | Drug therapy | Index Medicus | Abridged Index Medicus
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4. Full Text IL-33 amplifies both T(h)1-and T(h)2-type responses through its activity on human basophils, allergen-reactive T(h)2 cells, iNKT and NK Cells
by Smithgall, MD and Comeau, MR and Yoon, BRP and Kaufman, D and Armitage, R and Smith, DE
INTERNATIONAL IMMUNOLOGY, ISSN 0953-8178, 08/2008, Volume 20, Issue 8, pp. 1019 - 1030
IL-33 is an IL-1 family member recently identified as the ligand for T1/ST2 (ST2), a member of the IL-1 receptor family. ST2 is stably expressed on mast cells... 
NK cells | T(h)1/T(h)2 cells | MAST-CELLS | EFFECTOR FUNCTION | INNATE IMMUNE-RESPONSE | CD4(+) T-CELLS | IMMUNOLOGY | RECEPTOR ACCESSORY PROTEIN | inflammation | HUMAN IGE SYNTHESIS | cytokines | SOLUBLE ST2 PROTEIN | HUMAN TH2 CELLS | T1/ST2 EXPRESSION | ACUTE EXACERBATION
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5. Full Text Stem cell factor suppressed IL-33-induced MHC class II expression in murine bone marrow-derived mast cells
by Ito, Tomonobu and Egusa, Chizu and Maeda, Tatsuo and Numata, Takafumi and Nakano, Nobuhiro and Nishiyama, Chiharu and Tsuboi, Ryoji
Allergology International, ISSN 1323-8930, 04/2019, Volume 68, Issue 2, pp. 264 - 267
ST2 | PROTEIN | IMMUNOLOGY | ALLERGY | IL-33
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6. Full Text Combined use of high-sensitivity ST2 and NTproBNP to improve the prediction of death in heart failure
by Bayes-Genis, Antoni and de Antonio, Marta and Galán, Amparo and Sanz, Héctor and Urrutia, Agustin and Cabanes, Roser and Cano, Lucía and González, Beatriz and Díez, Cristanto and Pascual, Teresa and Elosúa, Roberto and Lupón, Josep
European Journal of Heart Failure, ISSN 1388-9842, 1/2012, Volume 14, Issue 1, pp. 32 - 38
Aims To address the incremental usefulness of biomarkers from different disease pathways for predicting risk of death in heart failure (HF). Methods and... 
Heart failure | ST2 | Prognosis | MORTALITY | SURVIVAL | DIAGNOSIS | CARDIAC & CARDIOVASCULAR SYSTEMS | GUIDELINES | SOLUBLE ST2 | FAMILY-MEMBER ST2 | THERAPY | DYSFUNCTION | ACUTE DYSPNEA | NT-PROBNP | Interleukin-1 Receptor-Like 1 Protein | Predictive Value of Tests | Risk Assessment - methods | Confidence Intervals | Natriuretic Peptide, Brain - analysis | Follow-Up Studies | Humans | Natriuretic Peptide, Brain - metabolism | Receptors, Cell Surface - analysis | Heart Failure - physiopathology | Male | Ventricular Remodeling | Immunoassay - methods | Female | Heart Failure - diagnosis | Heart Failure - mortality | Peptide Fragments - metabolism | Risk Factors | Proportional Hazards Models | Receptors, Cell Surface - metabolism | Heart Failure - metabolism | Peptide Fragments - analysis | Biomarkers | Death | Aged | Index Medicus
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7. Full Text Role of ST2 in Non - ST-elevation acute coronary syndrome in the MERLIN-TIMI 36 trial
by Kohli, Payal and Bonaca, Marc P and Kakkar, Rahul and Kudinova, Anastacia Y and Scirica, Benjamin M and Sabatine, Marc S and Murphy, Sabina A and Braunwald, Eugene and Lee, Richard T and Morrow, David A
Clinical Chemistry, ISSN 0009-9147, 01/2012, Volume 58, Issue 1, pp. 257 - 266
OBJECTIVE: We investigated the prognostic performance of ST2 with respect to cardiovascular death (CVD) and heart failure (HF) in patients with... 
MORTALITY | FAMILY-MEMBER ST2 | PROTEIN | HEART-FAILURE | ACUTE MYOCARDIAL-INFARCTION | RECEPTOR | MEDICAL LABORATORY TECHNOLOGY | NATRIURETIC PEPTIDE | BIOMARKER ST2 | SERUM-SOLUBLE ST2 | ACUTE DYSPNEA | Interleukin-1 Receptor-Like 1 Protein | Prognosis | Risk Assessment | Humans | Acute Coronary Syndrome - physiopathology | Male | Receptors, Cell Surface - blood | Piperazines - therapeutic use | Biomarkers - blood | Randomized Controlled Trials as Topic | Ranolazine | Acute Coronary Syndrome - drug therapy | Inflammation - metabolism | Acute Coronary Syndrome - diagnosis | Acetanilides - therapeutic use | Cardiovascular Diseases - mortality | Electrocardiography | Female | Aged | Heart Failure - diagnosis | Hemodynamics | Inflammation - diagnosis | Natriuretic Peptide, Brain - blood | Cardiovascular Diseases - diagnosis | Heart failure | Usage | Care and treatment | Heart cells | Diagnosis | Acute coronary syndrome | Biological markers | Properties | Studies | Cardiovascular disease | Heart attacks | Acute coronary syndromes | Index Medicus
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8. Full Text Elevated ST2 levels are associated with antibody‐mediated rejection in heart transplant recipients
by Grupper, Avishay and AbouEzzeddine, Omar F and Maleszewski, Joseph J and Grupper, Ayelet and Geske, Jennifer R and Kremers, Walter K and Kushwaha, Sudhir S and Pereira, Naveen L
Clinical Transplantation, ISSN 0902-0063, 09/2018, Volume 32, Issue 9, pp. e13349 - n/a
Soluble ST 2 ( sST 2) is a novel biomarker of inflammation and fibrosis. Elevated sST 2 levels (≥35 ng/mL) are associated with worse outcomes in patients with... 
Heart transplant | antibody‐mediated rejection | ST2 | antibody-mediated rejection | MORTALITY | SURGERY | DIAGNOSIS | SOLUBLE ST2 | VERSUS-HOST-DISEASE | IL-33 | TRANSPLANTATION | FAMILY-MEMBER ST2 | SERUM-LEVELS | ACUTE MYOCARDIAL-INFARCTION | WORKING FORMULATION | ACUTE DYSPNEA | Heart | Viral antibodies | Antibodies | Organ transplant recipients | Transplantation | Cardiac patients
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9. Full Text Endogenous IL-33 enhances T(h)2 cytokine production and T-cell responses during allergic airway inflammation
by Louten, J and Rankin, AL and Li, Y and Murphy, EE and Beaumont, M and Moon, C and Bourne, P and McClanahan, TK and Pflanz, S and Malefyt, RD
INTERNATIONAL IMMUNOLOGY, ISSN 0953-8178, 05/2011, Volume 23, Issue 5, pp. 307 - 315
IL-33 is an IL-1-related cytokine which has been implicated in T(h)2-associated biology and allergic diseases in humans and mice. IL-33 stimulates T(h)2 cells,... 
HUMAN BASOPHILS | TH2 CELLS | PROTEIN | EFFECTOR FUNCTION | MAST-CELLS | allergy | HMGB1 | IMMUNOLOGY | IL-33 | lung | ST2 | MURINE MODEL | T(h)2 cells | ASTHMA | cytokines | T1/ST2
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10. Full Text Elevations of inflammatory markers PTX3 and sST2 after resuscitation from cardiac arrest are associated with multiple organ dysfunction syndrome and early death
by Ristagno, Giuseppe and Varpula, Tero and Masson, Serge and Greco, Marta and Bottazzi, Barbara and Milani, Valentina and Aleksova, Aneta and Sinagra, Gianfranco and Assandri, Roberto and Tiainen, Marjaana and Vaahersalo, Jukka and Kurola, Jouni and Barlera, Simona and Montanelli, Alessandro and Latini, Roberto and Pettilä, Ville and Bendel, Stepani and Skrifvars, Markus B and for the FINNRESUSCI Study Group and FINNRESUSCI Study Grp and FINNRESUSCI Study Group
Clinical Chemistry and Laboratory Medicine (CCLM), ISSN 1434-6621, 10/2015, Volume 53, Issue 11, pp. 1847 - 1857
A systemic inflammatory response is observed after cardiopulmonary resuscitation. We investigated two novel inflammatory markers, pentraxin 3 (PTX3) and... 
ST2 | pentraxin 3 (PTX3) | cardiac arrest | C-REACTIVE PROTEIN | CARDIOPULMONARY | HEART-FAILURE | RECEPTOR | SOLUBLE ST2 | LONG PENTRAXIN PTX3 | FAMILY-MEMBER ST2 | EARLY INDICATOR | SERUM-LEVELS | MEDICAL LABORATORY TECHNOLOGY | INNATE IMMUNITY | Multiple Organ Failure - mortality | Humans | Middle Aged | Male | Biomarkers - blood | Receptors, Somatostatin - blood | Inflammation - blood | Serum Amyloid P-Component - analysis | Heart Arrest - mortality | Heart Arrest - blood | Female | Aged | Multiple Organ Failure - blood | C-Reactive Protein - analysis | Physiological aspects | Complications and side effects | Inflammation | Resuscitation | Cardiac arrest | Index Medicus
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11. Full Text Predictive value of low interleukin-33 in critically ill patients
by Krychtiuk, Konstantin A and Stojkovic, Stefan and Lenz, Max and Brekalo, Mira and Huber, Kurt and Wojta, Johann and Heinz, Gottfried and Demyanets, Svitlana and Speidl, Walter S
Cytokine, ISSN 1043-4666, 03/2018, Volume 103, pp. 109 - 113
Patients admitted to a medical intensive care unit (ICU) are characterized by an activated immune system and exhibit a high mortality rate irrespective of the... 
Critical care | SIRS | Soluble ST2 | Interleukin-33 | 30-day mortality | BIOCHEMISTRY & MOLECULAR BIOLOGY | IMMUNOLOGY | RECEPTOR ST2 | IL-33 | HUMAN ENDOTHELIAL-CELLS | CELL BIOLOGY | DEFINITIONS | ATTENUATES SEPSIS | INFLAMMATION | DISEASE | SOLUBLE ST2 PROTEIN | EXPRESSION | TISSUE FACTOR | Predictive Value of Tests | Intensive Care Units | Prospective Studies | Humans | Mortality | Critical Illness | Interleukin-1 Receptor-Like 1 Protein - blood | Female | Male | Aged | Interleukin-33 - blood | Index Medicus
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12. Full Text Interleukin 1 Receptor-Like 1 (IL1RL1) Promotes Airway Bacterial and Viral Infection and Inflammation
by Schaunaman, N and Sanchez, A and Dimasuay, KG and Pavelka, N and Numata, M and Alam, R and Martin, RJ and Chu, HW
INFECTION AND IMMUNITY, ISSN 0019-9567, 07/2019, Volume 87, Issue 7
Interleukin 1 receptor-like 1 (IL1RL1), also known as suppression of tumorigenicity 2 (ST2), is the receptor for interleukin 33 (IL-33) and has been... 
LUNG | CELLS | INFECTIOUS DISEASES | infection | VIRUS | IMMUNOLOGY | Mycoplasma | rhinovirus | NATIONAL HEART | ST2 | IL1Rl1 | IL-33/ST2 AXIS | HOST-DEFENSE | MICE | MYCOPLASMA-PNEUMONIAE INFECTION | neutrophils | ACUTE ASTHMA
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13. Full Text Significance of interleukin-33 and its related cytokines in patients with breast cancers
by Liu, Jing and Shen, Jia-Xin and Hu, Jia-Lin and Huang, Wen-He and Zhang, Guo-Jun
Frontiers in Immunology, ISSN 1664-3224, 2014, Volume 5, pp. 141 - 141
Interleukin-33 (IL-33) is a recently identified cytokine, an important member of the interleukin-1 family. IL-33 binds to its receptor ST2 to induce type 2... 
Immunosuppression | Breast cancer | Cytokines | Interleukin-33 | ST2/ST2L | breast cancer | interleukin-33
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14. Full Text Increased Expression of IL-33 in Severe Asthma: Evidence of Expression by Airway Smooth Muscle Cells
by Prefontaine, David and Lajoie-Kadoch, Stephane and Foley, Susan and Audusseau, Severine and Olivenstein, Ron and Halayko, Andrew J and Lemiere, Catherine and Martin, James G and Hamid, Qutayba
The Journal of Immunology, ISSN 0022-1767, 10/2009, Volume 183, Issue 8, pp. 5094 - 5103
IL-33, a new member of the IL-1 cytokine family, promotes Th2 inflammation, but evidence on the implications of this cytokine in asthma is lacking. IL-33 would... 
RESPONSES | TH2 CELLS | ST2 RECEPTOR | MAST-CELLS | EFFECTOR FUNCTION | NECROSIS-FACTOR-ALPHA | CYTOKINE | TNF-ALPHA | RELEASE | IMMUNOLOGY | T1/ST2 | Humans | Middle Aged | Male | Interleukins - genetics | Interleukin-4 - pharmacology | Dexamethasone - pharmacology | Asthma - immunology | Aged, 80 and over | Adult | Female | Interleukins - biosynthesis | Myocytes, Smooth Muscle - drug effects | Myocytes, Smooth Muscle - cytology | Myocytes, Smooth Muscle - metabolism | Biomarkers - metabolism | Antiviral Agents - pharmacology | Gene Expression | Lung - pathology | Anti-Inflammatory Agents - pharmacology | Interleukin-33 | Cells, Cultured | Interleukin-13 - pharmacology | Plicamycin - pharmacology | Plicamycin - analogs & derivatives | Drug Synergism | Transforming Growth Factor beta - pharmacology | Tumor Necrosis Factor-alpha - pharmacology | Up-Regulation - immunology | Myocytes, Smooth Muscle - immunology | Aged | Asthma - pathology | Interferon-gamma - pharmacology | Lung - immunology | Index Medicus | Abridged Index Medicus
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15. Full Text Galectin-3 and IL-33/ST2 axis roles and interplay in dietinduced steatohepatitis
by Pejnovic, Nada and Jeftic, Ilija and Jovicic, Nemanja and Arsenijevic, Nebojsa and Lukic, Miodrag L
World Journal of Gastroenterology, ISSN 1007-9327, 2016, Volume 22, Issue 44, pp. 9706 - 9717
Galectin-3; Liver fibrosis; Interleukin-33; ST2; Nonalcoholic steatohepatitis
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16. Full Text ST2 Predicts Mortality and Length of Stay in a Critically III Noncardiac Intensive Care Unit Population
by Rudolf, JW and Lewandrowski, EL and Lewandrowski, KB and Januzzi, JL and Bajwa, EK and Baron, JM
AMERICAN JOURNAL OF CLINICAL PATHOLOGY, ISSN 0002-9173, 02/2016, Volume 145, Issue 2, pp. 203 - 210
Objectives: The biomarker suppression of tumorigenicity 2 (ST2) is a well-established clinical biomarker of cardiac strain and is frequently elevated in a... 
hsTnT | CELLS | PROTEIN | MYOCARDIAL-INFARCTION | High-sensitivity troponin T | LONG-TERM MORTALITY | SOLUBLE ST2 | PATHOLOGY | ST2 | Cardiac biomarker | Suppression of tumorigenicity 2 | FAMILY-MEMBER ST2 | DECOMPENSATED HEART-FAILURE | TROPONIN-T | Clinical decision support | EMERGENCY-DEPARTMENT PATIENTS | INTERLEUKIN-1 RECEPTOR
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17. Full Text Blockade of IL-33/ST2 ameliorates airway inflammation in a murine model of allergic asthma
by Lee, Hea Yon and Rhee, Chin Kook and Kang, Ji Young and Byun, Ji Hae and Choi, Joon Young and Kim, Seung Joon and Kim, Young Kyoon and Kwon, Soon Suk and Lee, Sook Young
Experimental Lung Research, ISSN