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stable prostacyclin analog (99) 99
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iloprost (31) 31
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stable analogs (11) 11
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vasodilator agents - pharmacology (11) 11
stable prostacyclin analogs (10) 10
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therapy (10) 10
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nitric oxide (9) 9
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prostaglandins (9) 9
acute myocardial-infarction (8) 8
adult (8) 8
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chemistry, medicinal (7) 7
dogs (7) 7
epoprostenol - administration & dosage (7) 7
hypertension, pulmonary - physiopathology (7) 7
iloprost - administration & dosage (7) 7
inhibition (7) 7
ischemia (7) 7
ischemia-reperfusion injury (7) 7
lipids (7) 7
medicine & public health (7) 7
peripheral vascular-disease (7) 7
pgi2 (7) 7
pharmacokinetics (7) 7
platelet aggregation inhibitors - administration & dosage (7) 7
prostaglandin analogs (7) 7
stable isotopes (7) 7
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a stable analogs (6) 6
aggregation (6) 6
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dose-response relationship, drug (6) 6
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platelet aggregation (6) 6
platelet aggregation inhibitors - therapeutic use (6) 6
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Journal Article
BBA - Molecular and Cell Biology of Lipids, ISSN 1388-1981, 04/2016, Volume 1861, Issue 4, pp. 285 - 293
Brite adipocytes recently discovered in humans are of considerable importance in energy expenditure by converting energy excess into heat. This property could... 
UCP1 | Obesity | Prostacyclin | cPGI2 | cAMP | Brown adipocyte | CELLS | STABLE PROSTACYCLIN ANALOG | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | ADULT HUMANS | BROWN ADIPOSE-TISSUE | ARACHIDONIC-ACID | BERAPROST SODIUM | CELL BIOLOGY | BIOPHYSICS | PHARMACOKINETICS | PATHWAY | POLYUNSATURATED FATTY-ACIDS | Receptors, Epoprostenol | Adipocytes, Brown - metabolism | Adipogenesis - drug effects | Humans | Ion Channels - genetics | Infant | Male | Mitochondrial Proteins - genetics | PPAR gamma - metabolism | Receptors, Prostaglandin - metabolism | Dose-Response Relationship, Drug | Adipocytes, White - drug effects | Transfection | RNA Interference | Time Factors | Mitochondrial Proteins - metabolism | Epoprostenol - pharmacology | Cyclic AMP-Dependent Protein Kinases - metabolism | Adipocytes, Brown - drug effects | Cells, Cultured | PPAR alpha - genetics | Epoprostenol - analogs & derivatives | Phenotype | Receptors, Prostaglandin - agonists | Ion Channels - metabolism | Signal Transduction - drug effects | PPAR gamma - agonists | PPAR alpha - agonists | Enzyme Activation | PPAR alpha - metabolism | Thermogenesis - drug effects | Uncoupling Protein 1 | Anti-Obesity Agents - pharmacology | Adipocytes, White - metabolism | Energy Metabolism - drug effects | Unsaturated fatty acids | Metabolites | Arachidonic acid | Cells
Journal Article
NEUROSCIENCE, ISSN 0306-4522, 09/2010, Volume 170, Issue 1, pp. 317 - 323
We and others have identified that inhibition of cyclooxygenase might not be the optimal approach to limiting brain damage after stroke. Now we are... 
STABLE PROSTACYCLIN ANALOG | prostacyclin | BRAIN-INJURY | REPERFUSION INJURY | NEUROSCIENCES | MICE LACKING | SYNTHASE | mouse | beraprost sodium | INFARCTION | cerebral ischemia | COX-2 INHIBITORS | TRANSIENT | middle cerebral artery occlusion
Journal Article
Thrombosis and Haemostasis, ISSN 0340-6245, 2015, Volume 113, Issue 4, pp. 735 - 747
Summary Pulmonary vasodilators and prostacyclin therapy in particular, have markedly improved the outcome of patients with pulmonary hypertension (PH).... 
Endothelium and Angiogenesis | Prostacyclin analogues | Vascular remodelling | Vasculogenesis | Endothelial progenitor cells | Stem cells | PROGENITOR CELLS | vasculogenesis | prostacyclin analogues | PULMONARY ARTERIAL-HYPERTENSION | ISCHEMIA-REPERFUSION INJURY | STABLE PROSTACYCLIN ANALOGS | endothelial progenitor cells | CONGENITAL HEART-DISEASE | IN-VIVO | vascular remodelling | BLOOD-VESSELS | LUNG FIBROBLASTS | PERIPHERAL VASCULAR DISEASE | GROWTH-FACTOR | PROSTAGLANDIN ENDOPEROXIDES | HEMATOLOGY | Neovascularization, Physiologic - drug effects | Up-Regulation | Antihypertensive Agents - pharmacology | Humans | Child, Preschool | Hypertension, Pulmonary - physiopathology | Infant | Male | Vascular Endothelial Growth Factor A - metabolism | Hypertension, Pulmonary - blood | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Vascular Endothelial Growth Factor A - genetics | Dose-Response Relationship, Drug | Young Adult | Transfection | RNA Interference | Mesenchymal Stem Cells - drug effects | Adult | Endothelial Progenitor Cells - transplantation | Epoprostenol - pharmacology | Female | Hypertension, Pulmonary - drug therapy | Angiogenesis Inducing Agents - pharmacology | Child | Mesenchymal Stem Cells - metabolism | Endothelial Progenitor Cells - metabolism | Cell Survival - drug effects | Endothelial Progenitor Cells - drug effects | Cells, Cultured | Vascular Endothelial Growth Factor A - blood | Biomarkers - blood | Antibodies - pharmacology | Cell Lineage | Epoprostenol - analogs & derivatives | Animals | Signal Transduction - drug effects | Cell Differentiation - drug effects | Mice, Nude | Paracrine Communication - drug effects | Adolescent | Cell Proliferation - drug effects
Journal Article
Journal Article
Journal Article
THROMBOSIS AND HAEMOSTASIS, ISSN 0340-6245, 04/2005, Volume 93, Issue 4, pp. 743 - 750
Prostacyclin (PGI(2)) has beneficial cytoprotective properties, is a potent inhibitor of platelet aggregation and has been reported to improve microcirculatory... 
endothelium | APOPTOSIS | STABLE PROSTACYCLIN ANALOG | LOW-DOSE PROSTACYCLIN | drotrecogin alfa (activated) | prostacyclin | MICROCIRCULATION | IDENTIFICATION | ILOPROST | cyclooxyge-nase-2 | PROSTAGLANDINS | INFLAMMATION | SEPTIC SHOCK | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | activated protein C | SEVERE SEPSIS
Journal Article
Journal Article
Deutsche Medizinische Wochenschrift, ISSN 0012-0472, 10/2015, Volume 140, Issue 20, pp. 1486 - 1489
Journal Article