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Blood, ISSN 0006-4971, 04/2012, Volume 119, Issue 17, pp. 3997 - 4008
Journal Article
Immunity, ISSN 1074-7613, 02/2011, Volume 34, Issue 2, pp. 213 - 223
Type I interferon (IFN) is a common therapy for autoimmune and inflammatory disorders, yet the mechanisms of action are largely unknown. Here we showed that... 
FAMILIAL MEDITERRANEAN FEVER | MULTIPLE-SCLEROSIS | CASPASE-1 | HOST-DEFENSE | INNATE | CRYSTALS | RECOMBINANT INTERLEUKIN-1 | MICE | BACTERIAL-INFECTION | IMMUNOLOGY | RECEPTOR ANTAGONIST | Interleukin-1 - genetics | Inflammasomes - metabolism | STAT1 Transcription Factor - deficiency | NLR Family, Pyrin Domain-Containing 3 Protein | Humans | Monocytes - metabolism | Monocytes - immunology | Interleukin-10 - physiology | Interleukin-1 - biosynthesis | Interferon-beta - therapeutic use | Interferon Type I - biosynthesis | STAT3 Transcription Factor - physiology | Candida albicans - physiology | Interferon Type I - physiology | Caspase 1 - physiology | Candidiasis - immunology | Carrier Proteins - physiology | Peritonitis - etiology | STAT1 Transcription Factor - physiology | Poly I-C - pharmacology | Disease Susceptibility | Mice, Inbred C57BL | Peritonitis - immunology | STAT1 Transcription Factor - genetics | Gene Expression Regulation - drug effects | Animals | Candidiasis - etiology | Caspase 1 - genetics | Caspase 1 - deficiency | Interferon Type I - genetics | Multiple Sclerosis - immunology | Multiple Sclerosis - pathology | Apoptosis Regulatory Proteins - physiology | Cells, Cultured - metabolism | Mice | Interferon Inducers - pharmacology | Multiple Sclerosis - drug therapy | Interferon | Infections | Cytokines | Viral infections | Molecular weight | Immune system
Journal Article
Immunity, ISSN 1074-7613, 03/2014, Volume 40, Issue 3, pp. 367 - 377
Follicular helper T (Tfh) cells are required for the establishment of T-dependent B cell memory and high affinity antibody-secreting cells. We have revealed... 
EFFECTOR | CD4 T-CELLS | BCL6 | GENERATION | MUTATIONS | INDUCTION | IMMUNOLOGY | EXPRESSION | IL-21 | CENTER B-CELL | CUTTING EDGE | Lymphocytic choriomeningitis virus - immunology | Germinal Center - immunology | Transcriptome | Gene Expression Profiling | Lymphocytic Choriomeningitis - immunology | CD4-Positive T-Lymphocytes - immunology | Cell Differentiation - genetics | Lymphocytic Choriomeningitis - metabolism | STAT1 Transcription Factor - metabolism | Antibody Specificity - immunology | T-Lymphocytes, Helper-Inducer - immunology | STAT3 Transcription Factor - deficiency | T-Lymphocytes, Helper-Inducer - cytology | Interferon Type I - metabolism | B-Lymphocytes - metabolism | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | CD4 Antigens - genetics | Lymphocytic Choriomeningitis - genetics | T-Lymphocytes, Helper-Inducer - metabolism | Signal Transduction | CD4-Positive T-Lymphocytes - cytology | CD4-Positive T-Lymphocytes - metabolism | Gene Expression Regulation | Mice, Knockout | B-Lymphocytes - drug effects | Animals | B-Lymphocytes - immunology | Germinal Center - metabolism | Interferon Type I - genetics | Antibodies, Viral - immunology | Mice | Immunoglobulin Class Switching - genetics | Virus diseases | Interferon | Biological response modifiers | T cells | Health aspects | Proteins | Scholarships & fellowships | Transcription factors | Lymphocytes | Rodents | Ligands | T cell receptors | Infections | Viral infections
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 11/2013, Volume 210, Issue 12, pp. 2739 - 2753
Journal Article
NATURE, ISSN 0028-0836, 02/2011, Volume 470, Issue 7333, pp. 264 - 264
Journal Article
Journal Article
Journal Article
GLIA, ISSN 0894-1491, 02/2011, Volume 59, Issue 2, pp. 242 - 255
There is increasing evidence that astrocytes play important roles in immune regulation in the brain. Astrocytes express toll-like receptors (TLR) and build up... 
Brain | NFκB | Inflammation | Stat1 | Glia | Rodent | LPS | TOLL-LIKE-RECEPTORS | FOCAL CEREBRAL-ISCHEMIA | EXPERIMENTAL STROKE | brain | glia | NEUROSCIENCES | REGULATORY FACTOR-3 | inflammation | INNATE IMMUNE-RESPONSES | rodent | ENDOTHELIAL-CELLS | GENE-EXPRESSION | REACTIVE ASTROCYTES | SPINAL-CORD-INJURY | STAT1 ACTIVATION | NF kappa B | Enzyme-Linked Immunosorbent Assay - methods | Gene Expression Regulation, Enzymologic - drug effects | RNA, Small Interfering - genetics | Flow Cytometry - methods | STAT1 Transcription Factor - deficiency | NF-kappa B - metabolism | RNA, Messenger - metabolism | Cerebral Cortex - cytology | STAT1 Transcription Factor - metabolism | Drug Interactions | Transfection | Time Factors | Histone Acetyltransferases - metabolism | Phosphorylation - drug effects | Animals, Newborn | Astrocytes - drug effects | Microglia - drug effects | Mice, Inbred C57BL | RNA, Small Interfering - pharmacology | Enzyme Inhibitors - pharmacology | Myeloid Differentiation Factor 88 - genetics | Rats | Signal Transduction - genetics | Enzyme Activation - drug effects | STAT1 Transcription Factor - genetics | Rats, Sprague-Dawley | Toll-Like Receptor 4 - metabolism | Mice, Knockout | Tyrosine - metabolism | Animals | Myeloid Differentiation Factor 88 - deficiency | NF-kappa B - genetics | Signal Transduction - drug effects | Gene Expression Regulation, Enzymologic - genetics | Lipopolysaccharides - pharmacology | Mitogen-Activated Protein Kinases - genetics | Signal Transduction - physiology | Mice | Myeloid Differentiation Factor 88 - metabolism | Astrocytes - metabolism | Mitogen-Activated Protein Kinases - metabolism
Journal Article
Journal Article
Journal of Immunology, ISSN 0022-1767, 07/2015, Volume 195, Issue 1, pp. 210 - 216
Journal Article