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Blood, ISSN 0006-4971, 01/2015, Volume 125, Issue 4, pp. 591 - 599
Journal Article
NATURE, ISSN 0028-0836, 02/2011, Volume 470, Issue 7333, pp. 264 - 264
Journal Article
Molecular Carcinogenesis, ISSN 0899-1987, 02/2013, Volume 52, Issue 2, pp. 155 - 166
The Janus kinase (JAK)/signal transducer and activator of transcription (STAT) signaling pathway is involved in immune function and cell growth. We evaluated... 
cigarette smoking | STAT | estrogen | JAK | colon cancer | NSAIDs | rectal cancer | SOCS | Colon cancer | Rectal cancer | Estrogen | Cigarette smoking | OXIDATIVE STRESS | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | RISK | ENERGY-BALANCE | INHIBITION | ONCOLOGY | JANUS KINASES | COLORECTAL-CANCER | INFLAMMATION | PHYSICAL-ACTIVITY | Smoking - adverse effects | Colonic Neoplasms - genetics | Receptors, Estrogen - metabolism | Colorectal Neoplasms - genetics | Humans | Middle Aged | STAT Transcription Factors - metabolism | STAT4 Transcription Factor - metabolism | TYK2 Kinase - metabolism | Suppressor of Cytokine Signaling 1 Protein | Male | Janus Kinases - metabolism | Interferon-gamma - metabolism | Case-Control Studies | Colonic Neoplasms - metabolism | Janus Kinase 1 - metabolism | STAT1 Transcription Factor - metabolism | Rectal Neoplasms - genetics | Janus Kinase 1 - genetics | Janus Kinase 2 - metabolism | Adult | Female | Interferon-gamma - genetics | Interleukin-6 - metabolism | Colorectal Neoplasms - metabolism | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Colonic Neoplasms - mortality | Genetic Predisposition to Disease | Interleukin-6 - genetics | Janus Kinases - genetics | Signal Transduction | Janus Kinase 2 - genetics | Suppressor of Cytokine Signaling Proteins - genetics | Survival Rate | STAT1 Transcription Factor - genetics | Rectal Neoplasms - mortality | STAT Transcription Factors - genetics | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | STAT4 Transcription Factor - genetics | Aged | Polymorphism, Single Nucleotide | Rectal Neoplasms - metabolism | Suppressor of Cytokine Signaling Proteins - metabolism | TYK2 Kinase - genetics | Aspirin | Analysis | Oncology, Experimental | Research | Public health | Smoking | Cancer | Genetic diversity | Kinases | Risk factors | Colorectal cancer | Index Medicus
Journal Article
Immunity, ISSN 1074-7613, 02/2013, Volume 38, Issue 2, pp. 250 - 262
Gene regulation by cytokine-activated transcription factors of the signal transducer and activator of transcription (STAT) family requires serine... 
RNA-POLYMERASE-II | ACTIVATION | IFN-GAMMA | MEDIATOR | GENE-EXPRESSION | TRANSACTIVATION DOMAIN | IMMUNOLOGY | SERINE PHOSPHORYLATION | PROMOTER | INNATE IMMUNITY | P-TEFB | Transcription, Genetic - drug effects | Phosphorylation | Oligonucleotide Array Sequence Analysis | Humans | STAT5 Transcription Factor - immunology | Cyclin-Dependent Kinase 8 - immunology | RNA Polymerase II - immunology | STAT5 Transcription Factor - genetics | STAT1 Transcription Factor - metabolism | Cyclin-Dependent Kinase 8 - genetics | STAT3 Transcription Factor - genetics | Fibroblasts - metabolism | Fibroblasts - virology | Promoter Regions, Genetic | STAT1 Transcription Factor - genetics | STAT1 Transcription Factor - immunology | Hep G2 Cells | Gene Expression Regulation - drug effects | Animals | Interleukin-6 - pharmacology | Signal Transduction - drug effects | Fibroblasts - drug effects | Interferon-gamma - immunology | Interleukin-6 - immunology | Cyclin-Dependent Kinase 8 - metabolism | RNA Polymerase II - genetics | Mice | STAT3 Transcription Factor - immunology | Vesiculovirus - physiology | Interferon-gamma - pharmacology | DNA microarrays | RNA | Analysis | Genes | Interferon | Universities and colleges | Biological response modifiers | Gene expression | Transcription factors | Cytokines | Cell cycle | Colleges & universities | Grants | RNA polymerase | Kinases | Experiments | Cancer | Index Medicus
Journal Article
Journal of Leukocyte Biology, ISSN 0741-5400, 05/2017, Volume 101, Issue 5, pp. 1181 - 1190
The interferon and T cell receptor signaling pathways mediate specific and combined contributions to IL‐10 regulation via STAT and BATF transcription factors.... 
gene regulation | Tr1 cells | signaling | Signaling | Gene regulation | ACTIVATION | Tr 1 cells | PERSISTENT LCMV INFECTION | RECEPTOR | IMMUNOLOGY | CUTTING EDGE | BETA | CELL BIOLOGY | IRF INTERACTIONS | RESPONSES | GENE | DIFFERENTIATION | HEMATOLOGY | IFN-ALPHA | Interferon-alpha - pharmacology | RNA, Small Interfering - genetics | STAT2 Transcription Factor - immunology | Humans | Basic-Leucine Zipper Transcription Factors - immunology | CD4-Positive T-Lymphocytes - immunology | CD3 Complex - genetics | CD28 Antigens - genetics | CD28 Antigens - antagonists & inhibitors | Basic-Leucine Zipper Transcription Factors - antagonists & inhibitors | Phosphorylation - drug effects | Binding Sites | STAT3 Transcription Factor - genetics | Signal Transduction | CD4-Positive T-Lymphocytes - cytology | Gene Expression Regulation | CD28 Antigens - immunology | Basic-Leucine Zipper Transcription Factors - genetics | STAT1 Transcription Factor - genetics | STAT1 Transcription Factor - antagonists & inhibitors | Cycloheximide - pharmacology | STAT1 Transcription Factor - immunology | Interferon-alpha - immunology | Antibodies - pharmacology | Enhancer Elements, Genetic | STAT2 Transcription Factor - antagonists & inhibitors | Interleukin-10 - genetics | CD3 Complex - immunology | STAT2 Transcription Factor - genetics | Protein Binding | Primary Cell Culture | STAT3 Transcription Factor - immunology | Protein Isoforms - immunology | STAT3 Transcription Factor - antagonists & inhibitors | Interleukin-10 - immunology | CD4-Positive T-Lymphocytes - drug effects | Protein Isoforms - genetics | RNA, Small Interfering - metabolism | Phosphorylation | Transcription factors | CD45RA antigen | Central nervous system | Lymphocytes T | Leucine | Recruitment | T-cell receptor | Signal transduction | Conserved sequence | Pathways | Lymphocytes | Stat1 protein | Immune system | Stat2 protein | RNA-mediated interference | Stat3 protein | Inflammation | T cell receptors | Gene expression | Ribonucleic acid--RNA | CD4 antigen | Leucine zipper proteins | Interleukin 10 | Interferon | Index Medicus | STAT2 Transcription Factor | Interleukin-10 | Interferon-alpha | CD3 Complex | Antibodies | Life Sciences | Cycloheximide | Immunology | Protein Isoforms | CD28 Antigens | STAT1 Transcription Factor | RNA, Small Interfering | STAT3 Transcription Factor | CD4-Positive T-Lymphocytes | Basic-Leucine Zipper Transcription Factors
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2013, Volume 131, Issue 6, pp. 1624 - 1634.e17
Journal Article
Immunity, ISSN 1074-7613, 03/2014, Volume 40, Issue 3, pp. 367 - 377
Follicular helper T (Tfh) cells are required for the establishment of T-dependent B cell memory and high affinity antibody-secreting cells. We have revealed... 
EFFECTOR | CD4 T-CELLS | BCL6 | GENERATION | MUTATIONS | INDUCTION | IMMUNOLOGY | EXPRESSION | IL-21 | CENTER B-CELL | CUTTING EDGE | Lymphocytic choriomeningitis virus - immunology | Germinal Center - immunology | Transcriptome | Gene Expression Profiling | Lymphocytic Choriomeningitis - immunology | CD4-Positive T-Lymphocytes - immunology | Cell Differentiation - genetics | Lymphocytic Choriomeningitis - metabolism | STAT1 Transcription Factor - metabolism | Antibody Specificity - immunology | T-Lymphocytes, Helper-Inducer - immunology | STAT3 Transcription Factor - deficiency | T-Lymphocytes, Helper-Inducer - cytology | Interferon Type I - metabolism | B-Lymphocytes - metabolism | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | CD4 Antigens - genetics | Lymphocytic Choriomeningitis - genetics | T-Lymphocytes, Helper-Inducer - metabolism | Signal Transduction | CD4-Positive T-Lymphocytes - cytology | CD4-Positive T-Lymphocytes - metabolism | Gene Expression Regulation | Mice, Knockout | B-Lymphocytes - drug effects | Animals | B-Lymphocytes - immunology | Germinal Center - metabolism | Interferon Type I - genetics | Antibodies, Viral - immunology | Mice | Immunoglobulin Class Switching - genetics | Virus diseases | Interferon | Biological response modifiers | T cells | Health aspects | Proteins | Scholarships & fellowships | Transcription factors | Lymphocytes | Rodents | Ligands | T cell receptors | Infections | Viral infections | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 01/2014, Volume 289, Issue 1, pp. 529 - 539
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma found in children and young adults. It is characterized by the expression of a number of skeletal... 
PROTEIN | MICRORNA BIOGENESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | Notch | Rhabdomyosarcoma | LEUKEMIA INHIBITORY FACTOR | Proliferation | Muscle Differentiation | p63 | DNA Methylation | miR-203 | MYOGENIC DIFFERENTIATION | PROGRESS | GENES | Leukemia Inhibitory Factor Receptor | MUSCLE PROGENITOR CELLS | EXPRESSION | JAK Kinase | DNA, Neoplasm - metabolism | Receptors, Notch - metabolism | Humans | Rhabdomyosarcoma - metabolism | Gene Expression Regulation, Neoplastic | Rhabdomyosarcoma - pathology | Male | Receptors, Notch - genetics | Neoplasm Proteins - metabolism | Cell Differentiation - genetics | Janus Kinase 1 - metabolism | STAT1 Transcription Factor - metabolism | Janus Kinase 1 - genetics | Tumor Suppressor Proteins - genetics | Female | Neoplasm Proteins - genetics | Genes, Tumor Suppressor | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Promoter Regions, Genetic | Tumor Suppressor Proteins - metabolism | Down-Regulation | MicroRNAs - biosynthesis | Signal Transduction - genetics | Transcription Factors - genetics | STAT1 Transcription Factor - genetics | Transcription Factors - metabolism | Animals | Mice, Nude | Receptors, OSM-LIF - genetics | Cell Line, Tumor | Mice | MicroRNAs - genetics | Receptors, OSM-LIF - metabolism | Rhabdomyosarcoma - genetics | DNA, Neoplasm - genetics | Index Medicus | Molecular Bases of Disease
Journal Article
Journal Article
Journal of Hepatology, ISSN 0168-8278, 2010, Volume 55, Issue 2, pp. 289 - 298