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Molecular Therapy - Nucleic Acids, ISSN 2162-2531, 12/2019, Volume 18, pp. 183 - 193
Accumulating evidence has uncovered long non-coding RNAs (lncRNAs) as central regulators in the pathogenesis of diverse human cancers including colorectal... 
ITIH4-AS1 | REST | colorectal cancer | FUS | STAT3
Journal Article
Artificial Cells, Nanomedicine, and Biotechnology, ISSN 2169-1401, 12/2019, Volume 47, Issue 1, pp. 3194 - 3201
Background: Angelica polysaccharide (AP) is disengaged from the roots of Angelica sinensis. The extensive pathological activities of AP have been discovered in... 
NF-κB | JAK2/STAT3 | angelica polysaccharide | microRNA-10a | lipopolysaccharide | Epilepsy | MIR-10A | APOPTOSIS | MATERIALS SCIENCE, BIOMATERIALS | ENGINEERING, BIOMEDICAL | DOWN-REGULATION | SINENSIS | PROTECTS | ISCHEMIA-REPERFUSION INJURY | NF-kappa B | LIVER-INJURY | PATHWAY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | EXPRESSION
Journal Article
Artificial Cells, Nanomedicine, and Biotechnology, ISSN 2169-1401, 12/2019, Volume 47, Issue 1, pp. 3664 - 3670
This study aimed to explore the role of obestatin R gene-related protein (OB-RGRP) in autocrine signal transduction of adipocytes. Primary rat adipocytes were... 
Obesity | OB-RGRP | JAK2 | leptin | leptin receptor | STAT3
Journal Article
Artificial Cells, Nanomedicine, and Biotechnology, ISSN 2169-1401, 12/2019, Volume 47, Issue 1, pp. 3153 - 3162
Alkannin (ALK) has anti-inflammatory and anti-tumour activities. We tried to probe the underlying functions of ALK in oral squamous carcinoma (OSCC) cells... 
oral squamous carcinoma | Alkannin | RECK | JAK1/STAT3 | microRNA-9 | PI3K/AKT | SHIKONIN | MATERIALS SCIENCE, BIOMATERIALS | ENGINEERING, BIOMEDICAL | RECK GENE | STAT3 | PROLIFERATION | CANCER | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | POOR-PROGNOSIS | RADIOTHERAPY | DISTANT METASTASES | MIR-9 | EXPRESSION
Journal Article
by Jeong, GJ and Kang, D and Kim, AK and Han, KH and Jeon, HR and Kim, DI
SCIENTIFIC REPORTS, ISSN 2045-2322, 04/2019, Volume 9, Issue 1, pp. 6112 - 9
Stem cell therapy has long been considered a promising mode of treatment for many incurable diseases. Human mesenchymal stem cells (hMSCs) have provided the... 
PROLIFERATION | CYCLE PROGRESSION | MULTIDISCIPLINARY SCIENCES | CLINICAL-TRIALS | EXPANSION | PLASTICITY | Cell proliferation | Phosphorylation | Phosphoenolpyruvic acid | Mesenchyme | Oxidative metabolism | Stat3 protein | AKT protein | Metabolism | Fructose | Sodium oxalate | Regeneration | Metabolites | Oxidative phosphorylation | Sodium | Oxalic acid | Fructose-1,6-diphosphate | Stem cells | Glycolysis | Hypoxia
Journal Article
Journal of Experimental and Clinical Cancer Research, ISSN 1756-9966, 03/2019, Volume 38, Issue 1, pp. 133 - 14
Background: Glioblastoma multiforme (GBM) is the most common and aggressive form of astrocytoma among adult brain tumors. Multiple studies have shown that long... 
ceRNA | GBM | ANXA2 | miR155HG | P-STAT3 | ACTIVATION | ANNEXIN-II | CELL-PROLIFERATION | EPITHELIAL-MESENCHYMAL TRANSITION | BREAST-CANCER | NONCODING RNA | INVASION | GENE | ONCOLOGY | TUMOR-SUPPRESSOR | Chromatin | MicroRNA | Gliomas | Analysis | Genes | Brain tumors | Luciferase | Stem cells | Development and progression | Gene expression | Phosphorylation | Breast cancer | Kinases | Patients | Studies | Proteins | Liver cancer | Cell growth | Medical prognosis | MicroRNAs | Cell cycle | Tumorigenesis | Tumors
Journal Article
Pharmacological Reports, ISSN 1734-1140, 12/2019, Volume 71, Issue 6, pp. 1067 - 1078
Journal Article
by Li, BH and Zhang, L and Zhao, JG and Tan, GC and Zhang, WW and Zhang, N and Tian, J and Qu, PP
INFECTIOUS AGENTS AND CANCER, ISSN 1750-9378, 06/2019, Volume 14, Issue 1, pp. 16 - 12
BackgroundCervical cancer is a common cancer among women worldwide and is closely related to high-risk human papillomavirus infection (HR-HPV). The immune... 
Flow cytometry | IMMUNE-RESPONSE | PROFILES | Cytokines | STAT3 | IMMUNOLOGY | IL-6 | HPV | High-grade squamous intraepithelial lesion | ONCOLOGY | Triage | Cervical lesions | EXPRESSION | T-CELLS
Journal Article
by Qin, WJ and Tian, Y and Zhang, J and Liu, WJ and Zhou, QM and Hu, S and Yang, F and Lu, L and Lu, HJ and Cui, SZ and Wen, L and Wei, SZ
SCIENTIFIC REPORTS, ISSN 2045-2322, 09/2019, Volume 9, Issue 1, pp. 1 - 12
As a key glycolysis enzyme, the significance of pyruvate dehydrogenase kinase 1 (PDK1) in the development of colorectal cancer (CRC) remains unknown. This... 
PYRUVATE-DEHYDROGENASE | SURVIVAL | PATHWAYS | CELLS | ONCOGENE | METABOLIC SWITCH | ANOIKIS | RESECTION | MULTIDISCIPLINARY SCIENCES | TUMOR | Reactive oxygen species | Cryptotanshinone | Liver | Colorectal carcinoma | Stat3 protein | Colorectal cancer | Pyruvic acid | Metastasis | Fibronectin | Metastases | Liver cancer | Blood circulation | Glycolysis | Anoikis | Matrix protein
Journal Article
Journal of Cellular Biochemistry, ISSN 0730-2312, 12/2019, Volume 120, Issue 12, pp. 19749 - 19763
Journal Article
Cell death discovery, ISSN 2058-7716, 2019, Volume 5, Issue 1, pp. 72 - 11
Glioblastoma is an incurable and highly aggressive brain tumor. Understanding therapeutic resistance and survival mechanisms driving this tumor type is key to... 
NF-κB protein | DIABLO protein | Brain tumors | Brain cancer | Glioma cells | Glioblastoma | Stat3 protein | Lethality | Tumor necrosis factor-α | Apoptosis
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 12/2019, Volume 145, pp. 312 - 320
The circadian rhythm is a widespread physiological phenomenon present in almost all forms of life and is constituted by a system of interlocked... 
Bioluminescence | STAT3 | PRX2 | REV-ERBα/β | Circadian rhythm | H2O2 | BMAL1
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 09/2019, Volume 10, Issue 1, pp. 4013 - 17
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 1 - 12
CD4+ T follicular helper (TFH) cells provide help to B cells and promote antibody-mediated immune responses. Increasing evidence supports the existence of TFH... 
Cytokines | Stat3 protein | Stat4 protein | Interleukin 12 | Lymphocytes T | CXCR3 protein | Cell differentiation | CD4 antigen | Interleukin 6 | Cell activation | Lymphocytes B | γ-Interferon | Interleukin 21 | Autoimmune diseases | Bcl-6 protein
Journal Article
Journal Article
Arthritis Research & Therapy, ISSN 1478-6362, 12/2019, Volume 21, Issue 1, pp. 1 - 11
Background Activated T and B cells participate in the development and progression of Sjögren’s syndrome (SS). Metformin, a first-line anti-diabetic drug,... 
Cytokines | Pathogenesis | Arthritis | Inflammation | Gene expression | Metabolism | Kinases | Cell growth | Animals | Lymphocytes | Cell cycle | Tumor necrosis factor-TNF | Diabetes | Drug dosages | STAT3 | B-lymphocyte | Sjögren’s syndrome | Metformin | AMP-activated protein kinase | TOR serine-threonine kinase | Th17 cells
Journal Article