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Cancer Research, ISSN 0008-5472, 06/2010, Volume 70, Issue 11, pp. 4335 - 4345
Journal Article
Journal of Clinical Immunology, ISSN 0271-9142, 6/2011, Volume 31, Issue 3, pp. 472 - 478
Leptin, one of the adipokines, functions as a hormone and a cytokine. In this investigation, we show for the first time that leptin, in a... 
Medical Microbiology | Biomedicine | Immunology | Internal Medicine | Infectious Diseases | activation markers | cytokines | B cells | PROTEIN-KINASE | TRANSDUCER | RECEPTOR | PROLIFERATION | IMMUNOLOGY | BLOOD MONONUCLEAR-CELLS | DEFICIENCY | PI3K/AKT | IMMUNE-RESPONSES | T-CELLS | Autoimmunity | Interleukin-6 - analysis | Janus Kinase 2 - biosynthesis | Mitogen-Activated Protein Kinase 3 - analysis | Humans | p38 Mitogen-Activated Protein Kinases - biosynthesis | p38 Mitogen-Activated Protein Kinases - analysis | Dose-Response Relationship, Drug | Signal Transduction - immunology | Inflammation - metabolism | Mitogen-Activated Protein Kinases - analysis | Mitogen-Activated Protein Kinase 3 - biosynthesis | Mitogen-Activated Protein Kinase 6 - analysis | Leptin - pharmacology | Phosphorylation - drug effects | Interleukin-10 - analysis | B-Lymphocytes - metabolism | Janus Kinase 2 - analysis | Enzyme-Linked Immunosorbent Assay | Lymphocyte Activation | Cells, Cultured | Mitogen-Activated Protein Kinases - biosynthesis | Receptors, Leptin - immunology | STAT3 Transcription Factor - analysis | Inflammation - immunology | Tumor Necrosis Factor-alpha - analysis | STAT3 Transcription Factor - biosynthesis | B-Lymphocytes - drug effects | B-Lymphocytes - immunology | Mitogen-Activated Protein Kinase 6 - biosynthesis | Interleukin-6 - biosynthesis | Interleukin-10 - biosynthesis | Receptors, Leptin - metabolism | Tumor Necrosis Factor-alpha - biosynthesis | Index Medicus
Journal Article
Circulation Research, ISSN 0009-7330, 08/2009, Volume 105, Issue 4, pp. 365 - 374
RATIONALE:The recent emergence of hydrogen sulfide (H2S) as a potent cardioprotective signaling molecule necessitates the elucidation of its cytoprotective... 
Hydrogen sulfide | Myocardial infarction | Cardioprotection | Nrf2 | Antioxidant signaling | PROTEIN-KINASE-C | OXIDATIVE STRESS | ISCHEMIA/REPERFUSION INJURY | ACTIVATION | CARDIAC & CARDIOVASCULAR SYSTEMS | myocardial infarction | INDUCTION | antioxidant signaling | ISCHEMIA-REPERFUSION INJURY | JAK-STAT PATHWAY | hydrogen sulfide | ANTIOXIDANT | cardioprotection | PERIPHERAL VASCULAR DISEASE | MYOCARDIAL INJURY | RAT-HEART | HEMATOLOGY | HSP90 Heat-Shock Proteins - biosynthesis | Oxidative Stress | Air Pollutants - pharmacology | Male | Cyclooxygenase 2 - biosynthesis | bcl-Associated Death Protein - biosynthesis | Cell Nucleus - metabolism | Thioredoxins - biosynthesis | Time Factors | Protein Kinase C - metabolism | bcl-X Protein - biosynthesis | Phosphorylation - drug effects | HSP70 Heat-Shock Proteins - biosynthesis | Hydrogen Sulfide - pharmacology | Heme Oxygenase-1 - biosynthesis | Cardiotonic Agents - pharmacology | Myocardial Infarction - metabolism | Mice, Inbred ICR | Mice, Knockout | Gene Expression Regulation - drug effects | STAT3 Transcription Factor - biosynthesis | Myocardial Reperfusion Injury - metabolism | Animals | Signal Transduction - drug effects | Active Transport, Cell Nucleus - drug effects | NF-E2-Related Factor 2 - metabolism | Mice | Myocardial Infarction - prevention & control | Troponin I - metabolism | Myocardial Reperfusion Injury - prevention & control | Index Medicus
Journal Article
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 09/2017, Volume 109, Issue 9
Background: The efficacy of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) in EGFR-mutant non-small cell lung cancer (NSCLC) is... 
SURVIVAL | ACTIVATION | INHIBITION | ONCOLOGY | EPIDERMAL-GROWTH-FACTOR | SENSITIVITY | LUNG-CANCER CELLS | DRUG-RESISTANCE | MUTATIONS | NF-KAPPA-B | FACTOR RECEPTOR | Lung Neoplasms - drug therapy | Adenocarcinoma of Lung | Humans | Lung Neoplasms - metabolism | Middle Aged | ErbB Receptors - genetics | Male | Phosphoproteins - antagonists & inhibitors | Phosphoproteins - metabolism | RNA, Messenger - biosynthesis | Adenocarcinoma - metabolism | Adaptor Proteins, Signal Transducing - antagonists & inhibitors | Aged, 80 and over | Adult | Female | Adenocarcinoma - genetics | Retrospective Studies | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Lung Neoplasms - genetics | ErbB Receptors - antagonists & inhibitors | ErbB Receptors - metabolism | Phosphoproteins - biosynthesis | Signal Transduction | RNA, Messenger - genetics | Phosphoproteins - genetics | Adenocarcinoma - drug therapy | STAT3 Transcription Factor - biosynthesis | Protein Kinase Inhibitors - administration & dosage | Animals | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Mice, Nude | Adaptor Proteins, Signal Transducing - genetics | Cell Line, Tumor | Adaptor Proteins, Signal Transducing - biosynthesis | Aged | Mice | Adaptor Proteins, Signal Transducing - metabolism | STAT3 Transcription Factor - antagonists & inhibitors | Index Medicus
Journal Article
Cancer Cell, ISSN 1535-6108, 05/2014, Volume 25, Issue 5, pp. 666 - 681
Journal Article
Immunity, ISSN 1074-7613, 09/2014, Volume 41, Issue 3, pp. 389 - 401
Journal Article
The Journal of Immunology, ISSN 0022-1767, 01/2004, Volume 172, Issue 1, pp. 567 - 576
The signaling mechanism by which the anti-inflammatory cytokine IL-10 mediates suppression of proinflammatory cytokine synthesis remains largely unknown.... 
RHEUMATOID-ARTHRITIS | TUMOR-NECROSIS-FACTOR | DNA-BINDING | HUMAN NEUTROPHILS | TYROSINE PHOSPHORYLATION | INTERLEUKIN-10 RECEPTOR | GENE-EXPRESSION | KAPPA-B-ALPHA | IMMUNOLOGY | HUMAN MONOCYTES | MONONUCLEAR PHAGOCYTES | Protein Binding - genetics | Protein Biosynthesis | Interleukin-6 - antagonists & inhibitors | Humans | Tumor Necrosis Factor-alpha - genetics | Immunoglobulins - genetics | Lipopolysaccharides - antagonists & inhibitors | RNA, Messenger - metabolism | Suppressor of Cytokine Signaling Proteins | Repressor Proteins - antagonists & inhibitors | Antigens, CD - metabolism | Trans-Activators - physiology | Protein Tyrosine Phosphatases - antagonists & inhibitors | RNA, Messenger - biosynthesis | Protein Tyrosine Phosphatases - genetics | Inflammation Mediators - physiology | Glycoproteins - genetics | DNA-Binding Proteins - physiology | Protein Tyrosine Phosphatases - biosynthesis | DNA-Binding Proteins - antagonists & inhibitors | Signal Transduction - genetics | DNA - metabolism | Down-Regulation - genetics | Macrophages - metabolism | Protein Tyrosine Phosphatase, Non-Receptor Type 2 | Repressor Proteins - biosynthesis | Up-Regulation - immunology | Interleukin-10 - antagonists & inhibitors | Lipopolysaccharides - pharmacology | Adenoviruses, Human - genetics | Interleukin-10 - immunology | Tumor Necrosis Factor-alpha - biosynthesis | Phosphorylation | Tissue Inhibitor of Metalloproteinase-1 - biosynthesis | Antigens, CD - biosynthesis | Receptors, Cell Surface | Receptors, IgG - biosynthesis | Receptors, IgG - antagonists & inhibitors | Interleukin-10 - physiology | Signal Transduction - immunology | Tissue Inhibitor of Metalloproteinase-1 - metabolism | Signaling Lymphocytic Activation Molecule Family Member 1 | Receptors, Tumor Necrosis Factor - antagonists & inhibitors | RNA, Messenger - antagonists & inhibitors | Receptors, Tumor Necrosis Factor, Type II | Trans-Activators - genetics | Inflammation Mediators - antagonists & inhibitors | Trans-Activators - biosynthesis | Immunoglobulins - biosynthesis | Macrophages - immunology | Inflammation Mediators - immunology | Receptors, Tumor Necrosis Factor - metabolism | Immune Sera - pharmacology | Proteins - physiology | Cells, Cultured | Glycoproteins - antagonists & inhibitors | Histocompatibility Antigens Class II - biosynthesis | Tissue Inhibitor of Metalloproteinase-1 - antagonists & inhibitors | Transcription Factors - antagonists & inhibitors | Transcription Factors - biosynthesis | Up-Regulation - genetics | DNA-Binding Proteins - genetics | DNA - antagonists & inhibitors | Glycoproteins - biosynthesis | Suppressor of Cytokine Signaling 3 Protein | Down-Regulation - immunology | Interleukin-6 - biosynthesis | Receptors, Tumor Necrosis Factor - biosynthesis | STAT3 Transcription Factor | Trans-Activators - antagonists & inhibitors | Genetic Vectors | DNA-Binding Proteins - biosynthesis | Tumor Necrosis Factor-alpha - antagonists & inhibitors | SOCS-3 protein | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
Cancer Research, ISSN 0008-5472, 04/2008, Volume 68, Issue 7, pp. 2391 - 2399
Journal Article
Journal Article