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Journal of allergy and clinical immunology, ISSN 0091-6749, 08/2015, Volume 136, Issue 2, pp. 402 - 412
.... Objectives We sought to define the clinical features that distinguish DOCK8 deficiency from other forms of HIES and CIDs, study the mutational spectrum of DOCK8 deficiency, and report... 
Allergy and Immunology | Primary combined immunodeficiency | autosomal recessive hyper-IgE syndrome | signal transducer and activator of transcription 3 | Molluscum contagiosum | hyper-IgE syndrome | dedicator of cytokinesis 8 | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Job Syndrome - genetics | Job Syndrome - mortality | Humans | Middle Aged | Child, Preschool | Male | Support Vector Machine | Virus Diseases - complications | Eosinophils - immunology | Immunoglobulin E - blood | CD4-Positive T-Lymphocytes - immunology | Bacterial Infections - genetics | Eosinophils - pathology | Virus Diseases - genetics | Child | Guanine Nucleotide Exchange Factors - deficiency | STAT3 Transcription Factor - genetics | Skin Diseases - mortality | Immunoglobulin M - genetics | Guanine Nucleotide Exchange Factors - genetics | Virus Diseases - immunology | Skin Diseases - immunology | Antigens, Viral - immunology | Phenotype | Skin Diseases - complications | Job Syndrome - complications | Adolescent | Survival Analysis | Virus Diseases - mortality | Mutation | STAT3 Transcription Factor - immunology | CD8-Positive T-Lymphocytes - immunology | Bacterial Infections - mortality | Job Syndrome - immunology | CD8-Positive T-Lymphocytes - pathology | Skin Diseases - genetics | Antigens, Bacterial - immunology | Infant | Antigens, Bacterial - blood | CD4-Positive T-Lymphocytes - pathology | Antigens, Viral - blood | Bacterial Infections - complications | Immunoglobulin E - genetics | Bacterial Infections - immunology | Adult | Female | Immunoglobulin M - blood | Guanine Nucleotide Exchange Factors - immunology | Lymphocyte Count | Genotype & phenotype | Immunoglobulins | Laboratories | Lymphocytes | Families & family life | Lymphomas | Viral infections | Deoxyribonucleic acid--DNA | Immunoglobulin M | Immunoglobulin E | CD8-Positive T-Lymphocytes | Life Sciences | Antigens, Viral | Bacterial Infections | Job Syndrome | CD4-Positive T-Lymphocytes | Virus Diseases | Skin Diseases | Antigens, Bacterial | Guanine Nucleotide Exchange Factors | STAT3 Transcription Factor | Eosinophils
Journal Article
Nature communications, ISSN 2041-1723, 2017, Volume 8, Issue 1, pp. 2176 - 15
...ARTICLE Type I interferon-mediated autoinflammation due to DNase II deficiency Mathieu P. Rodero et al. Microbial nucleic acid recognition serves as the major... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Endodeoxyribonucleases - immunology | Phosphorylation | Deoxyribonucleases - deficiency | Humans | RNA, Messenger - analysis | Male | Gene Expression Profiling | Erythroblasts - immunology | Signal Transduction - immunology | Deoxyribonucleases - immunology | STAT1 Transcription Factor - metabolism | Female | Endodeoxyribonucleases - deficiency | Child | STAT3 Transcription Factor - metabolism | Interferon-alpha - metabolism | Antiviral Agents - pharmacology | Hereditary Autoinflammatory Diseases - blood | Hereditary Autoinflammatory Diseases - enzymology | Hereditary Autoinflammatory Diseases - immunology | Interferon-alpha - immunology | Up-Regulation - drug effects | Deoxyribonucleases - genetics | Hematopoiesis - immunology | Endodeoxyribonucleases - genetics | Sequence Analysis, RNA | Interferon-alpha - blood | Adolescent | Mutation | Hereditary Autoinflammatory Diseases - genetics | Glomerulonephritis | Neonates | Deformation | Liver | Antibodies | α-Interferon | Microorganisms | Lymphocytes | Hematopoiesis | Peripheral blood | Anti-DNA antibodies | Stat1 protein | Enzyme-linked immunosorbent assay | Deoxyribonucleic acid--DNA | Deoxyribonuclease | Hematology | Anemia | Stat3 protein | Nucleic acids | Ribonucleic acid--RNA | Hemopoiesis | Signaling | Monocytes | Erythroblasts | Fibrosis | Interferon | Endonuclease | Life Sciences | Immunology
Journal Article
Journal of allergy and clinical immunology, ISSN 0091-6749, 04/2013, Volume 131, Issue 4, pp. 1146 - 1156.e5
Journal Article
Medicine (Baltimore), ISSN 0025-7974, 07/2012, Volume 91, Issue 4, pp. e1 - e19
Journal Article
Cardiovascular research, ISSN 1755-3245, 2009, Volume 84, Issue 2, pp. 201 - 208
.... We propose that IPostC confers its infarct-sparing effect via activation of the newly described prosurvival Survivor Activating Factor Enhancement (SAFE... 
Ischaemia | Infarction | Reperfusion | Postconditioning | Preconditioning | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Tumor Necrosis Factor-alpha - metabolism | Phosphorylation | Tumor Necrosis Factor-alpha - genetics | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | Glycogen Synthase Kinase 3 beta | Male | Phosphatidylinositol 3-Kinases - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Receptors, Tumor Necrosis Factor, Type I - metabolism | Tumor Necrosis Factor-alpha - deficiency | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Myocardial Reperfusion Injury - pathology | Receptors, Tumor Necrosis Factor, Type II - metabolism | Myocardial Infarction - pathology | Myocardium - metabolism | STAT3 Transcription Factor - deficiency | Flavonoids - pharmacology | Proto-Oncogene Proteins c-akt - metabolism | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Disease Models, Animal | Mice, Inbred C57BL | Myocardium - pathology | Tyrphostins - pharmacology | Myocardial Infarction - metabolism | Glycogen Synthase Kinase 3 - metabolism | Receptors, Tumor Necrosis Factor, Type I - genetics | Receptors, Tumor Necrosis Factor, Type II - genetics | Mice, Knockout | Receptors, Tumor Necrosis Factor, Type II - deficiency | Myocardial Reperfusion Injury - metabolism | Animals | Androstadienes - pharmacology | Signal Transduction - drug effects | Mice | Myocardial Infarction - prevention & control | Protein Kinase Inhibitors - pharmacology | STAT3 Transcription Factor - antagonists & inhibitors | Myocardial Reperfusion Injury - prevention & control | Proto-Oncogene Proteins c-akt - antagonists & inhibitors
Journal Article
Gastroenterology (New York, N.Y. 1943), ISSN 0016-5085, 09/2012, Volume 143, Issue 3, pp. 765 - 776.e3
.... IL-17 signaling facilitated production of IL-6, IL-1, and tumor necrosis factor-α by inflammatory... 
Gastroenterology and Hepatology | Immune Response | Myofibroblast | Bone Marrow-Derived Macrophages | Mouse Model | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Kupffer Cells - pathology | Liver - pathology | Carbon Tetrachloride | Humans | Transforming Growth Factor beta1 - metabolism | Hepatic Stellate Cells - metabolism | Receptors, Interleukin-17 - genetics | Interleukin-23 - genetics | Receptors, Interleukin-17 - deficiency | Interleukins - genetics | Liver Cirrhosis, Experimental - prevention & control | Liver - immunology | Time Factors | Bone Marrow Transplantation | Liver Cirrhosis, Alcoholic - immunology | Interleukin-6 - metabolism | STAT3 Transcription Factor - genetics | Interleukin-17 - administration & dosage | Liver Cirrhosis, Experimental - immunology | Signal Transduction | Liver Cirrhosis, Alcoholic - pathology | Liver - metabolism | Interleukin-17 - genetics | Genotype | Bile Ducts - surgery | Disease Progression | Mice, Knockout | Interleukin-17 - metabolism | Phenotype | Interleukins - deficiency | Mice | Liver Cirrhosis, Experimental - metabolism | Tumor Necrosis Factor-alpha - metabolism | Inflammation Mediators - administration & dosage | Liver Cirrhosis, Experimental - etiology | Interleukin-23 - deficiency | Ligation | Hepatic Stellate Cells - immunology | Inflammation Mediators - metabolism | STAT3 Transcription Factor - deficiency | Liver Cirrhosis, Experimental - pathology | Kupffer Cells - metabolism | Hepatic Stellate Cells - pathology | Cell Line | Interleukin-1 - metabolism | Collagen Type I - metabolism | Mice, Inbred C57BL | Gene Expression Regulation | Interleukin-17 - deficiency | Liver Cirrhosis, Experimental - genetics | Animals | Interleukins - administration & dosage | Kupffer Cells - immunology | Medical colleges | Liver diseases | Liver | Carbon tetrachloride | Transforming growth factors | Muscle proteins | Macrophages | Endothelium | Messenger RNA | Interleukins | Actin | Analysis | Collagen | Fibrosis | Liver cirrhosis | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article