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Immunity, ISSN 1074-7613, 03/2012, Volume 36, Issue 3, pp. 362 - 373
Although Th17 cells are known to promote tissue inflammation and autoimmunity, their role during cancer progression remains elusive. Here, we showed that... 
GROWTH-FACTOR-BETA | EFFECTOR T-CELLS | TGF-BETA | T(H)17 CELLS | ROR-GAMMA-T | SIGNALING PATHWAY | IL-17 | ADENOSINE | GENERATION | IMMUNOLOGY | CANCER | 5'-Nucleotidase - genetics | RNA, Small Interfering - genetics | Antigens, CD - genetics | DNA-Binding Proteins - metabolism | Th17 Cells - drug effects | T-Lymphocytes - metabolism | Th17 Cells - metabolism | Lymphocytes, Tumor-Infiltrating - metabolism | Transcription Factors - immunology | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Promoter Regions, Genetic | DNA-Binding Proteins - immunology | Mice, Inbred C57BL | Gene Expression Regulation | Mice, Transgenic | Binding Sites - genetics | Mice, Knockout | Transcription Factors - metabolism | Transforming Growth Factor beta - pharmacology | Animals | Interleukin-6 - pharmacology | Apyrase - genetics | Th17 Cells - immunology | T-Lymphocytes - immunology | Mice | STAT3 Transcription Factor - immunology | STAT3 Transcription Factor - antagonists & inhibitors | Lymphocytes, Tumor-Infiltrating - immunology | Autoimmunity | DNA binding proteins | T cells | Transforming growth factors | Proteins | Transcription factors | Statistical analysis | Plasmids | Rodents | Cytotoxicity | Deoxyribonucleic acid--DNA | Immune system | Cancer | Adenosine | CD8 antigen | Helper cells | Stat3 protein | Interleukin 23 | Inflammation | Lymphocytes T | Transforming growth factor- beta | Adoptive transfer | Immunosuppressive agents | Promoters | CD4 antigen | Interleukin 6 | Interleukin 1 | CD73 antigen | Ectonucleotidase | Differentiation | Tumors | Index Medicus | 5'-Nucleotidase | T-Lymphocytes | Interleukin-6 | Life Sciences | Lymphocytes, Tumor-Infiltrating | Immunology | Apyrase | RNA, Small Interfering | STAT3 Transcription Factor | Th17 Cells | Transcription Factors | Binding Sites | Transforming Growth Factor beta | Antigens, CD | DNA-Binding Proteins
Journal Article
Cancer Cell, ISSN 1535-6108, 05/2014, Volume 25, Issue 5, pp. 666 - 681
Journal Article
Immunity, ISSN 1074-7613, 02/2016, Volume 44, Issue 2, pp. 303 - 315
Journal Article
Immunity, ISSN 1074-7613, 05/2014, Volume 40, Issue 5, pp. 772 - 784
Journal Article
Immunity, ISSN 1074-7613, 03/2014, Volume 40, Issue 3, pp. 367 - 377
Follicular helper T (Tfh) cells are required for the establishment of T-dependent B cell memory and high affinity antibody-secreting cells. We have revealed... 
EFFECTOR | CD4 T-CELLS | BCL6 | GENERATION | MUTATIONS | INDUCTION | IMMUNOLOGY | EXPRESSION | IL-21 | CENTER B-CELL | CUTTING EDGE | Lymphocytic choriomeningitis virus - immunology | Germinal Center - immunology | Transcriptome | Gene Expression Profiling | Lymphocytic Choriomeningitis - immunology | CD4-Positive T-Lymphocytes - immunology | Cell Differentiation - genetics | Lymphocytic Choriomeningitis - metabolism | STAT1 Transcription Factor - metabolism | Antibody Specificity - immunology | T-Lymphocytes, Helper-Inducer - immunology | STAT3 Transcription Factor - deficiency | T-Lymphocytes, Helper-Inducer - cytology | Interferon Type I - metabolism | B-Lymphocytes - metabolism | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | CD4 Antigens - genetics | Lymphocytic Choriomeningitis - genetics | T-Lymphocytes, Helper-Inducer - metabolism | Signal Transduction | CD4-Positive T-Lymphocytes - cytology | CD4-Positive T-Lymphocytes - metabolism | Gene Expression Regulation | Mice, Knockout | B-Lymphocytes - drug effects | Animals | B-Lymphocytes - immunology | Germinal Center - metabolism | Interferon Type I - genetics | Antibodies, Viral - immunology | Mice | Immunoglobulin Class Switching - genetics | Virus diseases | Interferon | Biological response modifiers | T cells | Health aspects | Proteins | Scholarships & fellowships | Transcription factors | Lymphocytes | Rodents | Ligands | T cell receptors | Infections | Viral infections | Index Medicus
Journal Article
Molecular Cell, ISSN 1097-2765, 03/2012, Volume 45, Issue 6, pp. 777 - 789
Abnormal inflammatory signaling activation occurs commonly in cancer cells. However, how it is initiated and maintained and its roles in early stages of... 
BREAST-CANCER | PATHWAYS | CELLS | PHOSPHORYLATION | JNK | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROSTATE-CANCER | IN-VIVO | ALPHA | CYTOKINE | NF-KAPPA-B | CELL BIOLOGY | Mitogen-Activated Protein Kinase Kinases - genetics | Epithelial Cells - metabolism | Humans | JNK Mitogen-Activated Protein Kinases - metabolism | MicroRNAs - metabolism | NF-kappa B - metabolism | Mitogen-Activated Protein Kinase 9 - genetics | Transcription Factor RelA - genetics | Heat Shock Transcription Factors | DNA-Binding Proteins - metabolism | Mitogen-Activated Protein Kinase Kinases - metabolism | Inflammation - metabolism | Cell Transformation, Neoplastic - genetics | Estrogen Receptor alpha - metabolism | Female | Chemokine CCL2 - metabolism | JNK Mitogen-Activated Protein Kinases - genetics | Interleukin-6 - metabolism | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Promoter Regions, Genetic | Interleukin-6 - genetics | Breast - cytology | Mitogen-Activated Protein Kinase 9 - metabolism | Chemokine CCL2 - genetics | Epithelial Cells - pathology | Mice, Transgenic | Signal Transduction - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Transcription Factors - metabolism | Animals | NF-kappa B - genetics | Transcription Factor RelA - metabolism | Inflammation - genetics | Mice | Analysis | Tumors | Index Medicus
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 2013, Volume 210, Issue 10, pp. 2041 - 2056
Unresolved endoplasmic reticulum (ER) stress in the epithelium can provoke intestinal inflammation. Hypomorphic variants of ER stress response mediators, such... 
MEDICINE, RESEARCH & EXPERIMENTAL | UNFOLDED PROTEIN RESPONSE | INFLAMMATORY-BOWEL-DISEASE | EPITHELIAL-CELLS | COLORECTAL-CANCER | ULCERATIVE-COLITIS | IN-VIVO | COLITIS-ASSOCIATED CANCER | ENDOPLASMIC-RETICULUM STRESS | IMMUNOLOGY | NF-KAPPA-B | TUMOR-GROWTH | Index Medicus
Journal Article