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Molecular carcinogenesis, ISSN 0899-1987, 2013, Volume 52, Issue 2, pp. 155 - 166
The Janus kinase (JAK)/signal transducer and activator of transcription (STAT) signaling pathway is involved in immune function and cell growth... 
cigarette smoking | STAT | estrogen | JAK | colon cancer | NSAIDs | rectal cancer | SOCS | Colon cancer | Rectal cancer | Estrogen | Cigarette smoking | OXIDATIVE STRESS | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | RISK | ENERGY-BALANCE | INHIBITION | ONCOLOGY | JANUS KINASES | COLORECTAL-CANCER | INFLAMMATION | PHYSICAL-ACTIVITY | Smoking - adverse effects | Colonic Neoplasms - genetics | Receptors, Estrogen - metabolism | Colorectal Neoplasms - genetics | Humans | Middle Aged | STAT Transcription Factors - metabolism | STAT4 Transcription Factor - metabolism | TYK2 Kinase - metabolism | Suppressor of Cytokine Signaling 1 Protein | Male | Janus Kinases - metabolism | Interferon-gamma - metabolism | Case-Control Studies | Colonic Neoplasms - metabolism | Janus Kinase 1 - metabolism | STAT1 Transcription Factor - metabolism | Rectal Neoplasms - genetics | Janus Kinase 1 - genetics | Janus Kinase 2 - metabolism | Adult | Female | Interferon-gamma - genetics | Interleukin-6 - metabolism | Colorectal Neoplasms - metabolism | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Colonic Neoplasms - mortality | Genetic Predisposition to Disease | Interleukin-6 - genetics | Janus Kinases - genetics | Signal Transduction | Janus Kinase 2 - genetics | Suppressor of Cytokine Signaling Proteins - genetics | Survival Rate | STAT1 Transcription Factor - genetics | Rectal Neoplasms - mortality | STAT Transcription Factors - genetics | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | STAT4 Transcription Factor - genetics | Aged | Polymorphism, Single Nucleotide | Rectal Neoplasms - metabolism | Suppressor of Cytokine Signaling Proteins - metabolism | TYK2 Kinase - genetics | Aspirin | Analysis | Oncology, Experimental | Research | Public health | Smoking | Cancer | Genetic diversity | Kinases | Risk factors | Colorectal cancer
Journal Article
PLoS genetics, ISSN 1553-7404, 2010, Volume 6, Issue 2, p. e1000841
Journal Article
Immunity (Cambridge, Mass.), ISSN 1074-7613, 09/2012, Volume 37, Issue 3, pp. 501 - 510
.... We demonstrate that the development of T-bet+ Treg cells that potently inhibit T helper 1 (Th1) cell responses was dependent on the transcription factor STAT1 and occurred directly in response to interferon... 
Forkhead Transcription Factors - immunology | T-Lymphocytes, Regulatory - metabolism | STAT4 Transcription Factor - metabolism | T-Box Domain Proteins - immunology | Interferon-gamma - metabolism | Mice, 129 Strain | Th1 Cells - immunology | T-Lymphocytes, Regulatory - immunology | Th1 Cells - metabolism | Signal Transduction - immunology | STAT1 Transcription Factor - metabolism | Flow Cytometry | Time Factors | Forkhead Transcription Factors - metabolism | Interleukin-12 Receptor beta 2 Subunit - genetics | Interleukin-12 Receptor beta 2 Subunit - immunology | Cell Differentiation | Interferon-gamma - genetics | STAT4 Transcription Factor - immunology | Interleukin-12 - pharmacology | Receptors, CXCR3 - metabolism | Mice, Inbred C57BL | Cells, Cultured | Mice, Transgenic | Forkhead Transcription Factors - genetics | Reverse Transcriptase Polymerase Chain Reaction | STAT1 Transcription Factor - genetics | T-Box Domain Proteins - genetics | STAT1 Transcription Factor - immunology | T-Box Domain Proteins - metabolism | Mice, Knockout | Animals | Signal Transduction - drug effects | Receptors, CXCR3 - genetics | Receptors, CXCR3 - immunology | Cell Proliferation - drug effects | Interleukin-12 Receptor beta 2 Subunit - metabolism | Mice | Interferon-gamma - pharmacology
Journal Article
JOURNAL OF EXPERIMENTAL MEDICINE, ISSN 0022-1007, 03/2006, Volume 203, Issue 3, pp. 755 - 766
Journal Article
The Journal of experimental medicine, ISSN 1540-9538, 2007, Volume 204, Issue 1, pp. 65 - 71
Journal Article
Journal Article
The Journal of experimental medicine, ISSN 1540-9538, 2014, Volume 211, Issue 9, pp. 1807 - 1819
Journal Article
Nature immunology, ISSN 1529-2916, 2013, Volume 14, Issue 11, pp. 1190 - 1198
.... Many were bound and regulated by the key transcription factors T-bet, GATA-3, STAT4 and STAT6... 
STEM-CELLS | INTERFERON | INTEGRATIVE ANNOTATION | GENE-EXPRESSION | POPULATIONS | IMMUNOLOGY | GENOME-WIDE IDENTIFICATION | TRANSCRIPTION FACTOR | SEQ | CUTTING EDGE | REVEALS | GATA3 Transcription Factor - genetics | GATA3 Transcription Factor - immunology | STAT4 Transcription Factor - metabolism | STAT6 Transcription Factor - genetics | T-Box Domain Proteins - immunology | Th2 Cells - immunology | Transcriptome - immunology | Genetic Loci | Th1 Cells - immunology | RNA, Long Noncoding - immunology | Th1 Cells - metabolism | Th17 Cells - metabolism | Precursor Cells, T-Lymphoid - metabolism | Precursor Cells, T-Lymphoid - cytology | Th17 Cells - cytology | Cell Differentiation | GATA3 Transcription Factor - metabolism | STAT4 Transcription Factor - immunology | Signal Transduction | Gene Expression Regulation - immunology | Mice, Inbred C57BL | Molecular Sequence Annotation | Th2 Cells - cytology | RNA, Long Noncoding - genetics | STAT6 Transcription Factor - metabolism | STAT6 Transcription Factor - immunology | T-Box Domain Proteins - genetics | Th2 Cells - metabolism | T-Box Domain Proteins - metabolism | Animals | Protein Binding | Th17 Cells - immunology | STAT4 Transcription Factor - genetics | Mice | Th1 Cells - cytology | Precursor Cells, T-Lymphoid - immunology | Cell Movement | Physiological aspects | Genetic aspects | Research | Cell differentiation | Gene expression | T cells | Cell migration
Journal Article
PloS one, ISSN 1932-6203, 2018, Volume 13, Issue 7, p. e0198507
Journal Article
Journal Article