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Blood, ISSN 0006-4971, 08/2014, Volume 124, Issue 9, pp. 1460 - 1472
Journal Article
Blood, ISSN 0006-4971, 10/2012, Volume 120, Issue 17, pp. 3510 - 3518
CRLF2 rearrangements, JAK1/2 point mutations, and JAK2 fusion genes have been identified in Philadelphia chromosome (Ph)-like acute lymphoblastic leukemia... 
MAMMALIAN TARGET | RAPAMYCIN | IN-VITRO | ABERRANT STAT5 | RECEPTOR | OF-FUNCTION MUTATIONS | HEMATOLOGY | B-PROGENITOR | GENETIC ALTERATIONS | STAT5 ACTIVATION | CRLF2 | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - metabolism | TOR Serine-Threonine Kinases - metabolism | Humans | Immunoglobulins - genetics | Molecular Targeted Therapy | Immunoglobulins - metabolism | TOR Serine-Threonine Kinases - antagonists & inhibitors | Janus Kinase 1 - metabolism | STAT5 Transcription Factor - genetics | STAT5 Transcription Factor - metabolism | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | TOR Serine-Threonine Kinases - genetics | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - mortality | Janus Kinase 1 - genetics | Janus Kinase 2 - metabolism | Antineoplastic Agents - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | Receptors, Cytokine - metabolism | Drug Evaluation, Preclinical | Child | Philadelphia Chromosome | Receptors, Cytokine - genetics | Janus Kinase 2 - antagonists & inhibitors | Disease Models, Animal | Pyrazoles - pharmacology | Acute Disease | Janus Kinase 2 - genetics | Survival Rate | Signal Transduction - genetics | Janus Kinase 1 - antagonists & inhibitors | Sirolimus - pharmacology | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - genetics | Xenograft Model Antitumor Assays | Animals | Signal Transduction - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | Lymphoid Neoplasia
Journal Article
细胞研究:英文版, ISSN 1001-0602, 2014, Volume 24, Issue 12, pp. 1387 - 1402
Journal Article
by Ray, JP and Craft, J
NATURE IMMUNOLOGY, ISSN 1529-2908, 02/2015, Volume 16, Issue 2, pp. 139 - 140
Journal Article
Blood, ISSN 0006-4971, 05/2013, Volume 121, Issue 22, pp. 4541 - 4550
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 09/2014, Volume 24, Issue 18, pp. 4568 - 4574
STATs are transcription factors acting as intracellular signaling after stimulation with cytokines, growth factors and hormones. STAT5 is also constitutively... 
BCR/ABL expressing leukemia | Cell growth inhibition | Pimozide | STAT5 inhibitors | Apoptosis | IMPACT | CHEMISTRY, MEDICINAL | GROWTH | CHEMISTRY, ORGANIC | Leukemia
Journal Article
Journal Article
Cell, ISSN 0092-8674, 04/2014, Volume 157, Issue 3, pp. 714 - 725
Tissue regeneration is an orchestrated progression of cells from an immature state to a mature one, conventionally represented as distinctive cell subsets. A... 
MASS CYTOMETRY | BIOCHEMISTRY & MOLECULAR BIOLOGY | IMMUNOGLOBULIN | STAT5 | LYMPHOCYTES | MURINE | CELL BIOLOGY | STAT5 Transcription Factor - metabolism | B-Lymphocytes - cytology | Lymphopoiesis | Algorithms | Humans | Precursor Cells, B-Lymphoid - cytology | V(D)J Recombination | Interleukin-7 - metabolism | Analysis | Hematopoietic stem cells
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 04/2016, Volume 22, Issue 8, pp. 2051 - 2061
Journal Article
EMBO Molecular Medicine, ISSN 1757-4676, 03/2010, Volume 2, Issue 3, pp. 98 - 110
Journal Article
Nature, ISSN 0028-0836, 09/2015, Volume 525, Issue 7569, pp. 380 - 383
Whether cancer is maintained by a small number of stem cells or is composed of proliferating cells with approximate phenotypic equivalency is a central... 
CANCER-CELLS | MAINTENANCE | ACTIVATION | HEMATOPOIESIS | PATHWAY | CITED2 | MULTIDISCIPLINARY SCIENCES | IMATINIB | STAT5 | DIFFERENTIATION | HIF-1-ALPHA | Piperazines - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Cell Proliferation | Neoplastic Stem Cells - drug effects | Humans | Gene Expression Regulation, Neoplastic | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - genetics | PPAR gamma - metabolism | Thiazolidinediones - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - pharmacology | STAT5 Transcription Factor - metabolism | Benzamides - administration & dosage | Thiazolidinediones - therapeutic use | Benzamides - therapeutic use | Basic Helix-Loop-Helix Transcription Factors - metabolism | Neoplastic Stem Cells - metabolism | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - pathology | Neoplastic Stem Cells - pathology | Benzamides - pharmacology | Thiazolidinediones - pharmacology | Repressor Proteins - metabolism | Pyrimidines - administration & dosage | Piperazines - therapeutic use | Pyrimidines - pharmacology | Imatinib Mesylate | Piperazines - pharmacology | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Pyrimidines - therapeutic use | PPAR gamma - agonists | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - metabolism | Trans-Activators - metabolism | Life Sciences | Microbiology and Parasitology | Immunology | Bacteriology | Virology
Journal Article
Nature communications, ISSN 2041-1723, 2013, Volume 4, Issue 1, p. 2675
Journal Article