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The EMBO Journal, ISSN 0261-4189, 04/2011, Volume 30, Issue 8, pp. 1459 - 1472
Journal Article
Blood, ISSN 0006-4971, 01/2015, Volume 125, Issue 4, pp. 591 - 599
Journal Article
Nature, ISSN 0028-0836, 03/2014, Volume 507, Issue 7493, pp. 513 - 8
Journal Article
Immunity, ISSN 1074-7613, 02/2013, Volume 38, Issue 2, pp. 250 - 262
Gene regulation by cytokine-activated transcription factors of the signal transducer and activator of transcription (STAT) family requires serine... 
RNA-POLYMERASE-II | ACTIVATION | IFN-GAMMA | MEDIATOR | GENE-EXPRESSION | TRANSACTIVATION DOMAIN | IMMUNOLOGY | SERINE PHOSPHORYLATION | PROMOTER | INNATE IMMUNITY | P-TEFB | Transcription, Genetic - drug effects | Phosphorylation | Oligonucleotide Array Sequence Analysis | Humans | STAT5 Transcription Factor - immunology | Cyclin-Dependent Kinase 8 - immunology | RNA Polymerase II - immunology | STAT5 Transcription Factor - genetics | STAT1 Transcription Factor - metabolism | Cyclin-Dependent Kinase 8 - genetics | STAT3 Transcription Factor - genetics | Fibroblasts - metabolism | Fibroblasts - virology | Promoter Regions, Genetic | STAT1 Transcription Factor - genetics | STAT1 Transcription Factor - immunology | Hep G2 Cells | Gene Expression Regulation - drug effects | Animals | Interleukin-6 - pharmacology | Signal Transduction - drug effects | Fibroblasts - drug effects | Interferon-gamma - immunology | Interleukin-6 - immunology | Cyclin-Dependent Kinase 8 - metabolism | RNA Polymerase II - genetics | Mice | STAT3 Transcription Factor - immunology | Vesiculovirus - physiology | Interferon-gamma - pharmacology | DNA microarrays | RNA | Analysis | Genes | Interferon | Universities and colleges | Biological response modifiers | Gene expression | Transcription factors | Cytokines | Cell cycle | Colleges & universities | Grants | RNA polymerase | Kinases | Experiments | Cancer | Index Medicus
Journal Article
Blood, ISSN 0006-4971, 05/2013, Volume 121, Issue 22, pp. 4541 - 4550
Journal Article
Journal Article
Journal Article
Blood, ISSN 0006-4971, 10/2012, Volume 120, Issue 14, pp. 2843 - 2852
We investigated the therapeutic potential of JQ1, an inhibitor of the BET class of human bromodomain proteins, in B-cell acute lymphoblastic leukemia (B-ALL).... 
SELECTIVE-INHIBITION | REARRANGEMENT | TRANSLOCATION | PROTEIN | OF-FUNCTION MUTATIONS | HUMAN CANCERS | HEMATOLOGY | EXPRESSION | CELL-LINE | B-PROGENITOR | CRLF2 | Cell Proliferation | Oligonucleotide Array Sequence Analysis | Humans | Gene Expression Profiling | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | STAT5 Transcription Factor - genetics | STAT5 Transcription Factor - metabolism | Receptors, Interleukin-7 - genetics | Flow Cytometry | Chromatin Immunoprecipitation | Janus Kinase 2 - metabolism | Biomarkers, Tumor - metabolism | B-Lymphocytes - pathology | Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology | Real-Time Polymerase Chain Reaction | Receptors, Cytokine - genetics | Triazoles - therapeutic use | Receptors, Interleukin-7 - metabolism | RNA, Messenger - genetics | Risk Factors | Janus Kinase 2 - genetics | Transcription Factors - antagonists & inhibitors | Reverse Transcriptase Polymerase Chain Reaction | Proto-Oncogene Proteins c-myc - metabolism | Blotting, Western | Azepines - therapeutic use | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Xenograft Model Antitumor Assays | Animals | Gene Rearrangement | Nuclear Proteins - antagonists & inhibitors | Cell Line, Tumor | Mice, Inbred NOD | Biomarkers, Tumor - genetics | Mice | Proto-Oncogene Proteins c-myc - genetics | Apoptosis | Index Medicus | Abridged Index Medicus | Lymphoid Neoplasia
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 11/2008, Volume 205, Issue 12, pp. 2763 - 2779
Progressive loss of T cell functionality is a hallmark of chronic infection with human immunodeficiency virus 1 (HIV-1). We have identified a novel population... 
MEDICINE, RESEARCH & EXPERIMENTAL | SKEWED MATURATION | ACTIVATION | MULTIPLE-SCLEROSIS | IMMUNODEFICIENCY-VIRUS-INFECTION | IMPAIRED FUNCTION | CD4(+) | IMMUNOLOGY | CHRONIC VIRAL-INFECTION | DISEASE PROGRESSION | LYMPHOCYTES | ANTIGEN | GATA3 Transcription Factor - genetics | T-Lymphocyte Subsets - immunology | Antigens, CD - immunology | HIV-1 - pathogenicity | T-Lymphocyte Subsets - cytology | GATA3 Transcription Factor - immunology | Humans | STAT5 Transcription Factor - immunology | T-Box Domain Proteins - immunology | Antigens, CD - genetics | Extracellular Signal-Regulated MAP Kinases - genetics | Extracellular Signal-Regulated MAP Kinases - immunology | HIV Infections - immunology | STAT5 Transcription Factor - genetics | Signal Transduction - immunology | HIV Infections - pathology | Apoptosis Regulatory Proteins - genetics | Apoptosis Regulatory Proteins - immunology | Membrane Proteins - genetics | p38 Mitogen-Activated Protein Kinases - genetics | Membrane Proteins - immunology | p38 Mitogen-Activated Protein Kinases - immunology | Hepatitis A Virus Cellular Receptor 2 | T-Box Domain Proteins - genetics | Disease Progression | Antiretroviral Therapy, Highly Active | HIV-1 - immunology | Phenotype | Animals | T-Lymphocytes - cytology | HIV Infections - drug therapy | Programmed Cell Death 1 Receptor | T-Lymphocytes - immunology | HIV Infections - physiopathology | HLA Antigens | Index Medicus
Journal Article