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Inflammatory Bowel Diseases, ISSN 1078-0998, 11/2011, Volume 17, Issue 11, pp. 2224 - 2234
Background: Interleukin 13 (IL-13) is upregulated in ulcerative colitis (UC) and increases colon epithelial permeability by inducing apoptosis and expression... 
STAT6 transcription factor | ulcerative colitis | interleukin‐13 | cell membrane permeability | suberoylanilide hydroxamic acid | interleukin-13 | NK-T-CELLS | REED-STERNBERG CELLS | CROHNS-DISEASE | CYTOKINE | INFLAMMATORY-BOWEL-DISEASE | HODGKIN LYMPHOMA | HISTONE DEACETYLASE INHIBITORS | GASTROENTEROLOGY & HEPATOLOGY | NF-KAPPA-B | EXPRESSION | Crohn Disease - genetics | RNA, Small Interfering - genetics | Up-Regulation | Phosphorylation | Epithelial Cells - metabolism | Apoptosis - drug effects | Epithelial Cells - drug effects | Humans | Colitis, Ulcerative - genetics | Colon - drug effects | Crohn Disease - metabolism | Male | STAT6 Transcription Factor - genetics | Case-Control Studies | Immunoenzyme Techniques | Claudins - metabolism | Female | STAT6 Transcription Factor - antagonists & inhibitors | Child | Hydroxamic Acids - pharmacology | Real-Time Polymerase Chain Reaction | Claudins - genetics | Signal Transduction | Colon - pathology | Colitis, Ulcerative - metabolism | RNA, Messenger - genetics | Cells, Cultured | Epithelial Cells - pathology | Colitis, Ulcerative - pathology | STAT6 Transcription Factor - metabolism | Interleukin-13 - pharmacology | Blotting, Western | Colon - metabolism | Crohn Disease - pathology | Histone deacetylase | Pediatrics | Inflammatory bowel diseases | Tight junctions | Transcription | Epithelial cells | Mucosa | Membrane permeability | Hydroxamic acid | Data processing | Crohn's disease | Interleukin 13 | siRNA | Epithelium | Transfection | Intestine | Stat6 protein | Colon | Apoptosis | Ulcerative colitis
Journal Article
Genome Biology, ISSN 1474-7596, 2016, Volume 17, Issue 1, p. 4
Background: The role of cytokines in establishing specific transcriptional programmes in innate immune cells has long been recognized. However, little is known... 
IL-4 | TET2 | Dendritic cell | DNA demethylation | STAT6 | differentiation | TRANSCRIPTION FACTORS | METHYLATION | INTERLEUKIN-4 | ACTIVATION | SPECIFICITY | NECROSIS-FACTOR-ALPHA | TARGET GENES | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | INFLAMMATION | GENETICS & HEREDITY | 5-HYDROXYMETHYLCYTOSINE | Monocytes - cytology | Humans | Interleukin-4 - metabolism | Gene Expression Regulation | Immunity, Innate - genetics | Monocytes - metabolism | Proto-Oncogene Proteins - genetics | DNA Methylation - genetics | Macrophage Colony-Stimulating Factor - metabolism | STAT6 Transcription Factor - genetics | STAT6 Transcription Factor - metabolism | DNA-Binding Proteins - genetics | Cell Differentiation - genetics | Dendritic Cells - cytology | Interleukin-4 - genetics | Macrophage Colony-Stimulating Factor - genetics | Transcription factors | Dendritic cells | Cytokines | Transcription | Granulocyte-macrophage colony-stimulating factor | Effector cells | Inflammation | Gene expression | Kinases | Signal transduction | Demethylation | Monocytes | Interleukin 4 | Cell activation | Stat6 protein | DNA methylation | Epigenetics | Tumor necrosis factor-TNF | Colony-stimulating factor | Genetic engineering | Methylation | Bioinformatics | Deoxyribonucleic acid--DNA | Metilació | Cèl·lules dendrítiques | DNA | Diferenciació cel·lular | Transcripció genètica | ADN | Genetic transcription | Cell diferentiation | Research
Journal Article
Journal of Immunology, ISSN 0022-1767, 05/2017, Volume 198, Issue 9, pp. 3737 - 3745
The transcription factor STAT6 plays a key role in mediating signaling downstream of the receptors for IL-4 and IL-13. In B cells, STAT6 is required for class... 
Transcriptome | STAT6 Transcription Factor - genetics | Th2 Cells - immunology | Phosphoproteins - metabolism | Cell Differentiation | Gene Expression Regulation - genetics | Gene Expression Regulation - immunology | Immunoglobulin E - metabolism | Cells, Cultured | Proteome | Phosphoproteins - genetics | STAT6 Transcription Factor - metabolism | Ki-1 Antigen - metabolism | STAT6 Transcription Factor - immunology | Mice, Knockout | CD79 Antigens - metabolism | Interleukin-4 - immunology | Animals | B-Lymphocytes - immunology | Adaptor Proteins, Signal Transducing - genetics | Mice | Mice, Inbred BALB C | CD79 Antigens - genetics | Adaptor Proteins, Signal Transducing - metabolism | Immunoglobulin Class Switching - genetics | Ki-1 Antigen - genetics | TARGET GENES | ACTIVATION | IN-VIVO | IL-4 | SIGNALING MECHANISMS | RECEPTOR | STAT6 | MICE | IMMUNOLOGY | EXPRESSION | LYMPHOCYTES | Lymphocyte receptors | Allergens | Post-transcription | Flow cytometry | Recombination | Immunoglobulin E | Immunity | SLP-76 protein | Proteins | Receptors | Interleukin 4 | CD30 antigen | Immune response | Mass spectroscopy | Liquid chromatography | Interleukin 13 | Functional analysis | Stat5 protein | Gene expression | Class switching | Fc receptors | Cytometry | Signaling | DNA microarrays | Lymphocytes B | Stat6 protein | Syk protein | Mass spectrometry
Journal Article
Nature Immunology, ISSN 1529-2908, 2013, Volume 14, Issue 11, pp. 1190 - 1198
Although intergenic long noncoding RNAs (lincRNAs) have been linked to gene regulation in various tissues, little is known about lincRNA transcriptomes in the... 
STEM-CELLS | INTERFERON | INTEGRATIVE ANNOTATION | GENE-EXPRESSION | POPULATIONS | IMMUNOLOGY | GENOME-WIDE IDENTIFICATION | TRANSCRIPTION FACTOR | SEQ | CUTTING EDGE | REVEALS | GATA3 Transcription Factor - genetics | GATA3 Transcription Factor - immunology | STAT4 Transcription Factor - metabolism | STAT6 Transcription Factor - genetics | T-Box Domain Proteins - immunology | Th2 Cells - immunology | Transcriptome - immunology | Genetic Loci | Th1 Cells - immunology | RNA, Long Noncoding - immunology | Th1 Cells - metabolism | Th17 Cells - metabolism | Precursor Cells, T-Lymphoid - metabolism | Precursor Cells, T-Lymphoid - cytology | Th17 Cells - cytology | Cell Differentiation | GATA3 Transcription Factor - metabolism | STAT4 Transcription Factor - immunology | Signal Transduction | Gene Expression Regulation - immunology | Mice, Inbred C57BL | Molecular Sequence Annotation | Th2 Cells - cytology | RNA, Long Noncoding - genetics | STAT6 Transcription Factor - metabolism | STAT6 Transcription Factor - immunology | T-Box Domain Proteins - genetics | Th2 Cells - metabolism | T-Box Domain Proteins - metabolism | Animals | Protein Binding | Th17 Cells - immunology | STAT4 Transcription Factor - genetics | Mice | Th1 Cells - cytology | Precursor Cells, T-Lymphoid - immunology | Cell Movement | Physiological aspects | Genetic aspects | Research | Cell differentiation | Gene expression | T cells | Cell migration
Journal Article
Journal Article