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sterile-20 kinase (47) 47
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by Ling, P and Lu, TJ and Yuan, CJ and Lai, MD
CELLULAR SIGNALLING, ISSN 0898-6568, 07/2008, Volume 20, Issue 7, pp. 1237 - 1247
Sterile 20 (ste20) protein is an upstream ser/thr kinase in yeast, and several mammalian Ste20-like (MST) kinases have been identified. This review focuses on... 
CHROMATIN CONDENSATION | OXIDANT STRESS | ste20 | CASPASE-MEDIATED ACTIVATION | CELL-PROLIFERATION | STERILE-20 KINASE | TYROSINE-PHOSPHATASE-PEST | STE20-LIKE PROTEIN-KINASE | NUCLEAR TRANSLOCATION | MST | CELL BIOLOGY | kinase | apoptosis contents | signal pathway | TUMOR-SUPPRESSOR RASSF1A | PROMOTES APOPTOSIS
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2012, Volume 7, Issue 1, p. e30983
The mammalian ste20 kinase (MST) signaling pathway plays an important role in the regulation of apoptosis and cell cycle control. We sought to understand the... 
CELL CONTACT INHIBITION | APOPTOSIS | OXIDATIVE-STRESS | RECEPTOR-GAMMA | HISTONE H2B | PHOSPHORYLATION | BIOLOGY | GENE-EXPRESSION | HIPPO PATHWAY | STERILE-20 KINASE | ADIPOGENESIS | Phosphorylation | Protein Interaction Domains and Motifs - physiology | Humans | Extracellular Signal-Regulated MAP Kinases - metabolism | Adipocytes - physiology | PPAR gamma - metabolism | Gene Knockdown Techniques | Cell Cycle Proteins - antagonists & inhibitors | Cell Differentiation - genetics | Protein Interaction Domains and Motifs - genetics | HEK293 Cells | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Cell Cycle Proteins - genetics | Protein Stability | Protein-Serine-Threonine Kinases - metabolism | Protein-Serine-Threonine Kinases - physiology | Cell Cycle Proteins - metabolism | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | 3T3-L1 Cells | PPAR gamma - physiology | Animals | Adipocytes - metabolism | Protein Binding | Mice | HeLa Cells | Enzyme Activation - genetics | Cell Cycle Proteins - physiology | Homeostasis | Homology | Activation | Biochemistry | Adipocytes | Kinases | Proteins | Signal transduction | Cell growth | Rodents | Cell cycle | Tumorigenesis | Adipogenesis | Binding | Mammals | Metabolism | Gene expression | Medicine | Signaling | Insects | Scaffolding | Stem cells | Regulatory mechanisms (biology) | Rosiglitazone | Differentiation | Binding sites | Apoptosis
Journal Article
Cell, ISSN 0092-8674, 06/2006, Volume 125, Issue 5, pp. 987 - 1001
Oxidative stress influences cell survival and homeostasis, but the mechanisms underlying the biological effects of oxidative stress remain to be elucidated.... 
TRANSCRIPTION FACTORS | FAT-BODY | NEURONAL SURVIVAL | CAENORHABDITIS-ELEGANS | HISTONE H2B | PHOSPHORYLATION | PROTEIN-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL-CYCLE | STERILE-20 KINASE | PROMOTES APOPTOSIS | CELL BIOLOGY | Phosphorylation | Conserved Sequence - physiology | Active Transport, Cell Nucleus - physiology | Oxidative Stress - physiology | Caenorhabditis elegans Proteins - metabolism | Nerve Tissue Proteins - chemistry | Forkhead Transcription Factors - metabolism | Forkhead Transcription Factors - chemistry | Neurons - metabolism | Protein-Serine-Threonine Kinases - metabolism | Animals, Newborn | Protein Structure, Tertiary | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | Cellular Senescence - physiology | Rats | Caenorhabditis elegans Proteins - isolation & purification | 14-3-3 Proteins - metabolism | Nerve Tissue Proteins - metabolism | Caenorhabditis elegans | Animals | Cell Death - physiology | Signal Transduction - physiology | Transcriptional Activation - physiology | Caenorhabditis elegans Proteins - genetics | Longevity - physiology | Evolution, Molecular | Genetic research | Oxidative stress | Genetic aspects | Research | Mammals | Cell death | Yuan (China) | Medical colleges | Neurosciences | Neurons | Stem cells | Protection and preservation | DNA binding proteins | Protein kinases
Journal Article
Stem Cell Research, ISSN 1873-5061, 04/2017, Volume 20, Issue C, pp. 42 - 49
Adult fibroblasts can be reprogrammed into induced pluripotent stem cells (iPSC) for use in various applications. However, there are challenges in iPSC... 
Cell proliferation | Hippo pathway | Reprogramming | iPSC | Mst1 | YES-ASSOCIATED PROTEIN | APOPTOSIS | YAP | CELL & TISSUE ENGINEERING | CELL BIOLOGY | TRANSITION | REGULATOR | INHIBITION | LATS2 | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENERATION | EXPRESSION | Cell Line | Cell Proliferation | Signal Transduction | Cell Survival | Proto-Oncogene Proteins - genetics | Proto-Oncogene Proteins - deficiency | Transcription Factors - genetics | Cellular Reprogramming | Mice, Knockout | Transcription Factors - metabolism | Hepatocyte Growth Factor - deficiency | Animals | Hepatocyte Growth Factor - genetics | Fibroblasts - cytology | Mice | Induced Pluripotent Stem Cells - cytology | Protein-Serine-Threonine Kinases - metabolism | Fibroblasts - metabolism | Induced Pluripotent Stem Cells - metabolism | Fibroblasts | Nuclear reprogramming | Research | YAP, Yes-associated protein | Bcl2, B-cell lymphoma 2 | Tbx3, T-box 3 | WT, wild type | Utf1, undifferentiated embryonic cell transcription factor 1 | Sav1, Salvador homologue 1 | iPSC, induced pluripotent stem cells | Mst1, mammalian sterile-20 like kinase 1 | Bax, Bcl2 associated X | Lats, large tumour suppressor homologue | MEF, mouse embryonic fibroblast | HIF1a, hypoxia inducible factor 1-alpha | Taz, WW domain containing transcription regulator 1 | Mob1, Mps one binder kinase activator-like 1 | Sox2, sex determining region Y box 2 | Methods and Reagents | Bim, Bcl2-like protein 11 | Oct4, octamer-binding transcription factor 4 | Klf 4, kruppel-like factor 4
Journal Article
American Journal of Physiology - Renal Physiology, ISSN 1931-857X, 01/2007, Volume 292, Issue 1, pp. 440 - 447
Reactive oxygen species, including hydrogen peroxide (H2O2), are generated during ischemia-reperfusion and are critically involved in acute renal failure. The... 
Oxidative stress | Phosphoinositide 3-kinase | Renal proximal tubular cells | Histone | Extracellular signaling-regulated kinase | SURVIVAL | PHYSIOLOGY | HISTONE H2B | INJURY | DEATH | STERILE-20 KINASE | PROTEIN-KINASE KINASE | CISPLATIN-INDUCED APOPTOSIS | GROWTH-FACTOR RECEPTOR | renal proximal tubular cells | PROXIMAL TUBULE CELLS | IN-VIVO | UROLOGY & NEPHROLOGY | histone | oxidative stress | phosphoinositide 3-kinase | extracellular signaling-regulated kinase | Apoptosis - drug effects | Epithelial Cells - drug effects | Kidney - enzymology | Oncogene Protein v-akt - antagonists & inhibitors | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | Phosphatidylinositol 3-Kinases - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Cell Nucleus - enzymology | Tetrazolium Salts | Caspase 3 - physiology | Thiazoles | Female | Kidney Tubules, Proximal - enzymology | Chromones - pharmacology | Hydrogen Peroxide - toxicity | Rabbits | Kidney Tubules, Proximal - pathology | Kidney - drug effects | Enzyme Inhibitors - pharmacology | Oxidants - toxicity | Morpholines - pharmacology | Adenoviridae - enzymology | Animals | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Epithelial Cells - enzymology | Histones - metabolism | Cell Nucleus - drug effects | Enzyme Activation - physiology | Adenoviridae - drug effects
Journal Article
BMB Reports, ISSN 1976-6696, 09/2011, Volume 44, Issue 9, pp. 584 - 589
The mammalian ste20-like kinase (MST) pathway is important in the regulation of apoptosis and cell cycle and emerges as a novel tumor suppressor pathway.... 
Phosphorylation | Cell death | Hippo | MST | SAV1 | APOPTOSIS | OXIDATIVE-STRESS | HISTONE H2B | BIOCHEMISTRY & MOLECULAR BIOLOGY | MST1 | HIPPO PATHWAY | YAP | PROLIFERATION | STERILE-20 KINASE | DROSOPHILA | CONTACT INHIBITION
Journal Article
Journal Article
Journal Article
Nature Reviews Molecular Cell Biology, ISSN 1471-0072, 03/2008, Volume 9, Issue 3, pp. 231 - 241
Journal Article
Current Molecular Medicine, ISSN 1566-5240, 06/2008, Volume 8, Issue 4, pp. 313 - 316
Journal Article
Journal Article