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The New England journal of medicine, ISSN 1533-4406, 2011, Volume 364, Issue 12, pp. 1126 - 1133
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2015, Volume 136, Issue 2, pp. 219 - 234
Immune-mediated (IM) adverse drug reactions (ADRs) are an underrecognized source of preventable morbidity, mortality, and cost. Increasingly, genetic variation... 
Allergy and Immunology | Stevens-Johnson syndrome | human herpesvirus | hapten | human leukocyte antigen | drug reaction with eosinophilia and systemic symptoms | altered peptide | major histocompatibility complex | p-i | heterologous immunity | carbamazepine | toxic epidermal necrolysis | T-cell receptor | pharmacogenomics | adverse drug reaction | Abacavir | allopurinol | pharmacogenetics | IMMUNOLOGY | INDUCED LIVER-INJURY | CUTANEOUS ADVERSE-REACTIONS | ALLERGY | STEVENS-JOHNSON-SYNDROME | INDUCED HYPERSENSITIVITY SYNDROME | GENOME-WIDE ASSOCIATION | HLA CLASS-I | NEVIRAPINE HYPERSENSITIVITY | IMPLEMENTATION CONSORTIUM GUIDELINES | HLA-B-ASTERISK-1502 ALLELE | Stevens-Johnson Syndrome - immunology | Humans | Virus Diseases - virology | Genetic Loci | HLA Antigens - genetics | Drug Hypersensitivity - genetics | Dideoxynucleosides - adverse effects | B-Lymphocytes - pathology | T-Lymphocytes - pathology | Virus Diseases - genetics | Drug Hypersensitivity - etiology | Pharmacogenetics | Virus Diseases - immunology | Stevens-Johnson Syndrome - etiology | Gene Expression Regulation | HLA Antigens - immunology | Drug Hypersensitivity - pathology | Models, Immunological | Stevens-Johnson Syndrome - genetics | B-Lymphocytes - immunology | Carbamazepine - adverse effects | Drug Hypersensitivity - immunology | Virus Diseases - pathology | Allopurinol - adverse effects | T-Lymphocytes - immunology | Stevens-Johnson Syndrome - pathology | Drugs | Allergy | Medical colleges | Analysis | Mortality | Models | Drug therapy | T cells | Allergic reaction | Drug allergy | Copyright | Patents | Peptides | Royalties | Lymphocytes | T cell receptors | Accreditation | Research | Disclosure | Allergies | T cell receptor | DRESS | abacavir | TEN | SJS
Journal Article
The Lancet (British edition), ISSN 0140-6736, 2017, Volume 390, Issue 10106, pp. 1996 - 2011
Summary During the past decade, major advances have been made in the accurate diagnosis of severe cutaneous adverse reactions (SCARs) to drugs, management of... 
Internal Medicine | GENERALIZED EXANTHEMATOUS PUSTULOSIS | MEDICINE, GENERAL & INTERNAL | RISK-FACTORS | INTRAVENOUS IMMUNOGLOBULIN | SYSTEMIC SYMPTOMS DRESS | REGULATORY T-CELLS | HYPERSENSITIVITY REACTIONS | LONG-TERM SEQUELAE | TOXIC EPIDERMAL NECROLYSIS | RETROSPECTIVE ANALYSIS | STEVENS-JOHNSON-SYNDROME | Severity of Illness Index | Diagnosis, Differential | Drug Hypersensitivity Syndrome - epidemiology | Prognosis | Drug Hypersensitivity Syndrome - diagnosis | Risk Assessment | Humans | Stevens-Johnson Syndrome - etiology | Drug-Related Side Effects and Adverse Reactions - etiology | Male | Stevens-Johnson Syndrome - diagnosis | Acute Generalized Exanthematous Pustulosis - epidemiology | Drug-Related Side Effects and Adverse Reactions - epidemiology | Incidence | Acute Generalized Exanthematous Pustulosis - diagnosis | Stevens-Johnson Syndrome - epidemiology | Acute Generalized Exanthematous Pustulosis - etiology | Female | Drug Hypersensitivity Syndrome - etiology | Drug-Related Side Effects and Adverse Reactions - diagnosis | Drugs | Complications and side effects | Skin | Edema | Stevens-Johnson syndrome | Complications | Pustulosis | Eosinophilia | Morbidity | Toxic epidermal necrolysis | Side effects | Scars | Pain | Lymphocytes | Gangrene | Diagnosis | Drug therapy | Physicians | Liver | Infections | Blood | Electrocardiography | Skin diseases | Failure | Lupus | Medical personnel | Enzymes | Immunoglobulins | Medical imaging | Mortality | Histology | Fever | Influenza
Journal Article
Epilepsy research, ISSN 0920-1211, 2011, Volume 97, Issue 1-2, pp. 190 - 197
Summary Background Although the US FDA recommends screening for HLA-B*1502 allele in most of Asian ancestry before initiating carbamazepine therapy, the HLA... 
Neurology | Hypersensitivity syndrome (HSS) | Human leukocyte antigen (HLA) | Toxic epidermal necrolysis (TEN) | Carbamazepine | Stevens–Johnson syndrome (SJS) | Stevens-Johnson syndrome (SJS) | B LOCUS | TOXIC EPIDERMAL NECROLYSIS | CLINICAL NEUROLOGY | RISK-FACTOR | CLASS-I | HYPERSENSITIVITY REACTIONS | DIVERSITY | HLA-B-ASTERISK-1502 ALLELE | JAPANESE PATIENTS | STEVENS-JOHNSON-SYNDROME | ASSOCIATION | Predictive Value of Tests | Humans | Middle Aged | Asian Continental Ancestry Group - genetics | Male | Drug Eruptions - ethnology | Young Adult | Stevens-Johnson Syndrome - chemically induced | Anticonvulsants - adverse effects | Epilepsy - ethnology | Stevens-Johnson Syndrome - ethnology | Adult | Epilepsy - genetics | Female | Drug Eruptions - genetics | Republic of Korea | Pharmacogenetics - statistics & numerical data | Genetic Predisposition to Disease - genetics | Histocompatibility Testing | Gene Frequency | Genotype | Histocompatibility Antigens Class I - genetics | Stevens-Johnson Syndrome - genetics | Carbamazepine - adverse effects | Epilepsy - drug therapy | Genetic Predisposition to Disease - ethnology | Aged | Asian Continental Ancestry Group - statistics & numerical data | Antigen-antibody reactions | Complications and side effects | Allergy | Medical colleges | Histocompatibility antigens | HLA histocompatibility antigens | Genetic aspects | Koreans | Allergic reaction
Journal Article
Nature medicine, ISSN 1546-170X, 2008, Volume 14, Issue 12, pp. 1343 - 1350
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2015, Volume 136, Issue 2, pp. 236 - 244
Drug hypersensitivity reactions are an important clinical problem for both health care and industry. Recent advances in genetics have identified a number of... 
Allergy and Immunology | crystallography | Drug hypersensitivity | HLA | genetic polymorphisms | mechanisms | COST-EFFECTIVENESS ANALYSIS | IMMUNOLOGY | TOXIC EPIDERMAL NECROLYSIS | CLOZAPINE-INDUCED AGRANULOCYTOSIS | INDUCED LIVER-INJURY | HLA-B LOCUS | NITROSO SULFAMETHOXAZOLE | CUTANEOUS ADVERSE-REACTIONS | T-CELL RESPONSES | ALLERGY | STEVENS-JOHNSON-SYNDROME | ABACAVIR HYPERSENSITIVITY | Stevens-Johnson Syndrome - immunology | Humans | HLA Antigens - genetics | HIV Infections - immunology | HIV Infections - pathology | Drug Hypersensitivity - genetics | Receptors, Antigen, T-Cell - immunology | Dideoxynucleosides - adverse effects | T-Lymphocytes - pathology | Drug Hypersensitivity - etiology | Pharmacogenetics | HIV Infections - genetics | HIV Infections - virology | Stevens-Johnson Syndrome - etiology | Gene Expression Regulation | HLA Antigens - immunology | Genetic Heterogeneity | Drug Hypersensitivity - pathology | Models, Immunological | Stevens-Johnson Syndrome - genetics | Carbamazepine - adverse effects | Drug Hypersensitivity - immunology | T-Lymphocytes - immunology | Receptors, Antigen, T-Cell - genetics | Stevens-Johnson Syndrome - pathology | Allergy | Histocompatibility antigens | Liver | HLA histocompatibility antigens | Genetic research | Health care industry | T cells | Allergic reaction | Methods | Carbamazepine | Drug allergy | Proteins | Studies | Hypotheses | Transplants & implants | Peptides | Genomes | Drug dosages | SJS, Stevens-Johnson syndrome | TEN, Toxic epidermal necrolysis | ADR, Adverse drug reaction | p-i, Pharmacologic interaction
Journal Article