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Cell, ISSN 0092-8674, 12/2012, Volume 151, Issue 7, pp. 1474 - 1487
Journal Article
Journal Article
Translational Cancer Research, ISSN 2218-676X, 06/2013, Volume 2, Issue 3, pp. 130 - 143
DNA double-stranded breaks (DSB) are among the most dangerous forms of DNA damage. Unrepaired DSBs results in cells undergoing apoptosis or senescence whereas... 
DNA-Ligase IV | DNA-PKcs | Ku70/80 | XLF | XRCC4 | Non-homologous end-joining | DNA double strand breaks | non-homologous end-joining | ONCOLOGY | Ku70
Journal Article
Genes and Development, ISSN 0890-9369, 02/2011, Volume 25, Issue 4, pp. 350 - 362
Repair of dsDNA breaks requires processing to produce 3'-terminated ssDNA. We biochemically reconstituted DNA end resection using purified human proteins:... 
BLM helicase | DNA2 nuclease | DNA break repair | EXO1 nuclease | DNA end resection | Homologous recombination | NUCLEASE ACTIVITY | BLOOMS-SYNDROME HELICASE | HUMAN EXONUCLEASE 1 | ESCHERICHIA-COLI | MISMATCH REPAIR | DEVELOPMENTAL BIOLOGY | DOUBLE-STRAND BREAK | SACCHAROMYCES-CEREVISIAE | CELL BIOLOGY | homologous recombination | GENETICS & HEREDITY | MRE11 NUCLEASE | MITOTIC RECOMBINATION | RECQ HELICASE | RecQ Helicases - metabolism | Humans | DNA Repair Enzymes - genetics | Replication Protein A - physiology | Multiprotein Complexes - genetics | RecQ Helicases - genetics | DNA Repair - genetics | DNA Breaks, Double-Stranded | DNA Breaks, Single-Stranded | DNA-Binding Proteins - metabolism | MRE11 Homologue Protein | Multiprotein Complexes - metabolism | Replication Protein A - genetics | DNA Repair Enzymes - metabolism | Cell Cycle Proteins - genetics | Exodeoxyribonucleases - genetics | Nuclear Proteins - genetics | DNA Helicases - genetics | RecQ Helicases - physiology | DNA Repair Enzymes - physiology | DNA-Binding Proteins - physiology | Cell Cycle Proteins - metabolism | Nuclear Proteins - metabolism | Replication Protein A - metabolism | DNA-Binding Proteins - genetics | Multiprotein Complexes - physiology | DNA Helicases - metabolism | Models, Biological | Exodeoxyribonucleases - metabolism | Exodeoxyribonucleases - physiology | Nuclear Proteins - physiology | In Vitro Techniques | Cell Cycle Proteins - physiology | DNA Helicases - physiology | Protein Binding - physiology | Index Medicus | Research Paper
Journal Article
PLoS Genetics, ISSN 1553-7390, 06/2008, Volume 4, Issue 6, pp. e1000110 - e1000110
Journal Article
Molecular Cell, ISSN 1097-2765, 10/2018, Volume 72, Issue 2, pp. 211 - 221.e3
Journal Article
Nature Communications, ISSN 2041-1723, 12/2017, Volume 8, Issue 1, pp. 1751 - 11
Journal Article
Advances in Protein Chemistry and Structural Biology, ISSN 1876-1623, 01/2019, Volume 115, pp. 69 - 94
DNA double strand breaks (DSB) are the most deleterious type of damage inflicted on DNA by various environmental factors and as consequences of normal cellular... 
Repair | Double-strand breaks | Chromatin
Journal Article
Journal Article